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A simple wound rinse might cut Post-Surgery bleeding

NCT ID NCT06270407

Recruiting now Disease control Sponsor: St. Olavs Hospital Source: ClinicalTrials.gov ↗

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This trial tests whether applying tranexamic acid (TXA) directly to the wound surface at the end of plastic surgery can reduce complications like re-bleeding, infection, or wound breakdown. About 3,000 adults having plastic surgery will receive either TXA or a saline placebo in a double-blind setup, meaning neither they nor their doctors know which they got. The main goal is to see if TXA lowers the need for interventions to stop bleeding within the first 10 days after surgery, while also checking for any increased risk of blood clots.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tranexamic acid applied directly to the wound surface
What this could lead to
If it works, this simple, low-cost approach could reduce bleeding and wound complications after plastic surgery, improving recovery and safety.
What could go wrong
The trial is still testing the idea, and results may not show a clear benefit. There is also a theoretical concern about increased blood clot risk, which the study will monitor.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SURGICAL COMPLICATION

Contacts and locations

Locations

  • Bærum Sykehus

    RECRUITING

    Gjettum, 1346, Norway

  • Haraldsplass Diakonale Sykehus

    RECRUITING

    Bergen, 5009, Norway

  • Helsinki University Hospital HUS

    RECRUITING

    Helsinki, 00029, Finland

  • Oslo Universitetssykehus Rikshospitalet

    RECRUITING

    Oslo, 0372, Norway

  • St Olav's University Hospital

    RECRUITING

    Trondheim, 7006, Norway

  • Stavanger Universitetssykehus SUS

    NOT_YET_RECRUITING

    Stavanger, 4017, Norway

  • Sykehuset Innlandet Hamar

    NOT_YET_RECRUITING

    Hamar, 2318, Norway

  • Sykehuset Innlandet Tynset

    RECRUITING

    Tynset, 2500, Norway

  • Sykehuset Nordmøre og Romsdal

    RECRUITING

    Hjelset, 6450, Norway

  • UNN Tromsø

    RECRUITING

    Tromsø, 9019, Norway

  • Vejle Sykehus

    RECRUITING

    Vejle, 7100, Denmark

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