St. Olavs Hospital

This trial tests whether applying tranexamic acid (TXA) directly to the wound surface at the end of plastic surgery can reduce complications like re-bleeding, infection, or wound breakdown. About 3,000 adults having plastic surgery will receive either TXA or a saline placebo in a…

This study tests a procedure called endovascular embolization for people with meningioma, a type of brain tumor. The procedure blocks blood vessels that feed the tumor, aiming to shrink it or stop its growth. Participants are adults with growing or symptomatic meningiomas that ar…

This study examines whether therapist-guided internet-based cognitive behavioral therapy (ICBT) works well and saves money when used in routine healthcare for moderate depression, social anxiety disorder, and panic disorder. About 800 adults with these conditions will receive up …

This trial tests whether using two defibrillators in rapid succession, rather than one, can improve survival in people whose hearts stop outside a hospital. The procedure, called double sequential external defibrillation (DSED), is normally tried only after several failed attempt…

This study examines whether adding structured high-intensity physical exercise to a 3-month residential treatment program for substance use disorder improves patients' physical health, mental health, and quality of life. Researchers measure changes in oxygen uptake, leg strength,…

This study follows 3,400 adults referred to a sleep clinic for insomnia or circadian rhythm sleep disorders. Participants receive standard care—such as light therapy, melatonin, and blue-light-blocking glasses—and track their progress through questionnaires and sleep diaries. The…

This trial compares two methods for fixing a tendon graft during ACL knee surgery: a newer button system (Endobutton CL BTB) versus standard metal screws. About 220 people having their first ACL reconstruction will be randomly assigned to one method. The study tracks knee functio…

This study tests whether a lab-grown mini-tumor (tumouroid) from a patient's biopsy can help doctors pick the more effective chemotherapy between two standard options (FOLFOX or FOLFIRI) for metastatic colorectal cancer. The trial enrolls adults with a specific type of colorectal…

This study tests whether different types of patient education—group classes, a website, or free dental hygiene samples—can improve drinking habits and oral care in people who have had bariatric surgery. Many patients face tooth decay and enamel erosion after surgery due to change…

This study tests whether taking atorvastatin (a widely used cholesterol-lowering drug) every day for 12 weeks can reduce the number of migraine days in people with chronic migraine. About 300 adults aged 18–64 with chronic migraine will receive either atorvastatin or a placebo pi…

This study tests whether adding tranexamic acid (a drug that helps blood clot) to standard surgery can lower the chance of needing another surgery for chronic subdural hematoma, a condition where blood collects around the brain. About 274 adults scheduled for surgery will be rand…

This study tests whether atorvastatin, a common cholesterol medicine, can prevent migraine attacks in adults with episodic migraine (4-14 attacks per month). Researchers will compare a 20mg dose, a 40mg dose, and a placebo over several months. The goal is to see if the drug reduc…

This trial tests a psychoeducational course for people who have recently experienced a suicide attempt or are at high risk. The course teaches participants and their family members to identify personal triggers and early warning signs, and to create an individual safety plan. The…

This trial tests whether giving the steroid dexamethasone for three days to children after their first severe wheezing episode (triggered by a rhinovirus) can prevent recurrent wheezing and asthma. The study enrolls children admitted to hospitals in Norway, Finland, and Sweden. R…

This trial looks at whether pregnant women at high risk for preeclampsia can safely stop taking daily aspirin at 24-28 weeks instead of continuing until 36 weeks. Around 300 women will be randomly assigned to either stop or continue aspirin. The goal is to see if stopping early l…

This trial tests whether a more intensive exercise program with in-person follow-up and repeated treadmill tests helps people with post-concussion symptoms and headaches recover better than a program with only phone-based follow-up. Participants will exercise at a level just belo…

This study tests whether up to 9 sessions of electroacupuncture can reduce pelvic pain in women with suspected endometriosis who are scheduled for diagnostic surgery. 38 women aged 18-45 with moderate to severe pain will be enrolled. The goal is to see if this treatment can impro…

This study tests a digital app called StartHjelp that provides information about mental health treatment, patient rights, and self-help strategies to adults waiting for outpatient care. The goal is to see if using the app improves patient satisfaction, engagement, and knowledge c…

This study tests whether a short educational program can help adults with ADHD feel more satisfied and confident in managing their condition. The program combines group sessions with digital materials, covering self-help tools and treatment options. Researchers will compare this …

This study tests whether adding a group-based stabilization and skill-training program to regular individual therapy helps people with long-lasting post-traumatic stress recover better. About 160 adults receiving outpatient mental health care will take part. Half will get the com…

This study tests whether chronotherapy—a combination of staying awake for 34 hours, light therapy, and a fixed sleep schedule—can quickly improve depression symptoms when added to standard care. 76 adults with moderate to severe depression will be randomly assigned to get chronot…

This study explores whether tight calf muscles (gastrocnemius tightness) are more common in otherwise healthy children who have foot or leg pain compared to those without pain. Researchers will measure ankle flexibility using the Silvferskiöld test in children referred to a pedia…

This study follows 400 people in Norway with multiple myeloma, plasma cell leukemia, or AL amyloidosis who are receiving newer immunotherapies like teclistamab, elranatamab, or CAR-T cell therapy outside of clinical trials. Researchers will track how well these treatments control…

This study follows 1600 breast cancer patients for up to 15 years to see if modern, lower-dose radiotherapy causes fewer heart problems than older methods. Researchers will use heart scans, blood tests, and ECGs to detect early signs of damage. The goal is to compare heart diseas…

This study tests a new, lightweight ultrasound device called NeoDoppler that can be gently placed on a newborn's soft spot (fontanelle) to continuously measure blood flow in the brain. Researchers will enroll 180 preterm and full-term infants, including those with conditions like…

This study looks at whether Goal Management Training (GMT) can improve cognitive control in people who have had a brain injury. About 116 adults will take part in group training sessions and some will also get smartphone reminders or a booster session. The goal is to find out wha…