Heart risks from breast cancer radiation under the microscope in landmark study

NCT ID NCT02541435

Recruiting now Knowledge-focused Sponsor: St. Olavs Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study follows 1600 breast cancer patients for up to 15 years to see if modern, lower-dose radiotherapy causes fewer heart problems than older methods. Researchers will use heart scans, blood tests, and ECGs to detect early signs of damage. The goal is to compare heart disease rates in these patients to the general female population and identify which radiation techniques are safest.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiotherapy (conventional and laser-assisted breath-controlled)
What this could lead to: If successful, this study could help doctors understand which radiotherapy techniques are safest for the heart, potentially reducing long-term cardiovascular risks for future breast cancer patients.
What could go wrong: This is an observational study, not a treatment trial. It will take 15 years to complete, and results may not apply to all patients or newer radiotherapy methods.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST NEOPLASMS CARDIOVASCULAR DISEASES

Contacts and locations

Locations

St Olavs University Hospital
RECRUITING

Trondheim, Norway
Ålesund Hospital
RECRUITING

Ålesund, Norway

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