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Mapping the virus: nationwide study seeks to uncover true COVID-19 spread

NCT ID NCT04658121

Knowledge-focused Sponsor: COVID-19 Prevention Network Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study aims to estimate how many people in various US communities have or have had the SARS-CoV-2 virus. Researchers will test blood and nasal swab samples from over 26,000 adults and children living in senior facilities, attending outpatient clinics, or residing in select neighborhoods. The findings will help determine the best locations for future COVID-19 treatment and prevention trials.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help identify the best communities for testing new COVID-19 treatments and vaccines.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly benefit participants. Results depend on accurate testing and community participation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

26,211 people

The number who actually took part.

Started

Feb 2021

Finished

Aug 2021

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults residing in nursing homes or attending outpatient healthcare facilities in neighborhoods of selected research sites. Adults and children (\>2 month of age) in neighborhoods of selected research sites.

Ages

2 months and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Adults residing in senior living facilities or attending outpatient healthcare facilities: * At least 18 years of age * Willing and able to provide informed consent or consent has been provided by legal representative (for those with mental incapacity in senior living facilities) * Recruited from a selected facility Adults and children from select neighborhoods of research site communities: * Adults and children \> 2 months of age * For individuals \< 18 years old, a guardian must be present (in person or by phone for those 15 - 17 years old) * Willing and able to provide consent (or assent for individuals 7-17 years old, parent/guardian will provide consent for all minors) * Recruited from a selected venue Exclusion Criteria: * Previous enrollment in this study, either from the same or another CRS community. * Any condition that, in the opinion of the study staff, would make participation in the study unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID-19

Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Bronx Prevention Center

    New York, New York, 10451, United States

  • Children's Hospital Colorado CRS

    Aurora, Colorado, 80045, United States

  • Cincinnati CRS

    Cincinnati, Ohio, 45229, United States

  • Harlem Prevention

    New York, New York, 10027, United States

  • John's Hopkins CRS

    Baltimore, Maryland, 21218, United States

  • New Jersey Medical School CRS

    Newark, New Jersey, 07103, United States

  • New Orleans Adolescent Trials Unit CRS

    New Orleans, Louisiana, 70118, United States

  • Penn Prevention CRS

    Philadelphia, Pennsylvania, 19104, United States

  • Physicians & Surgeons CRS

    New York, New York, 10032, United States

  • St. Louis University VTEU-CAIMED-PHSU

    Ponce, Puerto Rico

  • The Ponce de Leon Center CRS

    Atlanta, Georgia, 30308, United States

  • U of Miami, IDRU at Jackson Memorial Hospital CRS

    Miami, Florida, 33136, United States

  • UIC Project Wish CRS

    Chicago, Illinois, 60612, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

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