COVID vaccine booster in pregnancy: does it protect baby too?

NCT ID NCT05543993

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This completed study followed 150 pregnant or breastfeeding women who received a bivalent COVID-19 booster. Researchers measured antibody levels in mothers, infants, and breast milk to understand how vaccination impacts immunity against COVID-19 variants. The goal was to learn more about protection for both mother and child.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Bivalent COVID-19 Booster (Pfizer or Moderna)
What this could lead to
If successful, this study could help clarify how well COVID-19 vaccines protect both mothers and their babies.
What could go wrong
This is an observational study, not a treatment trial. Results may not apply to all populations or newer virus variants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Breast Feeding COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.