SpikoGen booster shows promise in small COVID-19 study

NCT ID NCT05542862

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study tested the SpikoGen vaccine as a booster shot in 81 adults who had already received a full course of any COVID-19 vaccine. The goal was to see if a third or fourth dose of SpikoGen could raise antibody levels and provide protection. Researchers measured immune responses and tracked safety, including any side effects or infections.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
SpikoGen vaccine (recombinant spike protein based COVID-19 vaccine)
What this could lead to
If successful, this could show that SpikoGen is a safe and effective booster option for people who received different types of COVID-19 vaccines.
What could go wrong
This is a small, completed Phase 3 trial with only 81 participants, so results may not apply to larger populations. The study focuses on antibody levels, not long-term protection against infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ARASMI

    Adelaide, South Australia, 5042, Australia

More trials for these conditions

Other studies related to the condition(s) this trial covers.