COVID-19
Clinical trials for COVID-19 explained in plain language.
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First human test of new COVID vaccine formula
⭐️ VACCINE ⭐️ TerminatedThis early-stage study tested a new mRNA vaccine designed to protect against COVID-19. It involved 182 healthy adults and aimed to check the vaccine's safety and measure the body's immune response over one year. The study was terminated early, and its main goal was to gather init…
Matched conditions: COVID-19
Phase: PHASE1, PHASE2 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: ⭐️ VACCINE ⭐️
Last updated Apr 01, 2026 14:43 UTC
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Researchers check how well the new COVID shot works against current variants
⭐️ VACCINE ⭐️ TerminatedThis study looked back at health records to see how well the updated 2024-2025 Pfizer/BioNTech COVID-19 vaccine protected people from getting sick with COVID-19. Researchers analyzed data from CVS MinuteClinic patients aged 5 and older who got tested for the virus and reported sy…
Matched conditions: COVID-19
Sponsor: Pfizer • Aim: ⭐️ VACCINE ⭐️
Last updated Apr 01, 2026 14:41 UTC
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Drug trial aims to stop COVID-19 from getting worse
Disease control TerminatedThis study tested a drug called ensovibep, given as an injection, to treat adults with early COVID-19 symptoms who were not in the hospital. The main goals were to see if the drug could reduce the amount of virus in the body and, more importantly, prevent people from needing to g…
Matched conditions: COVID-19
Phase: PHASE2, PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Early antibody trial for sick kids with COVID-19 halted
Disease control TerminatedThis early-stage study tested a single dose of lab-made antibodies (casirivimab+imdevimab) in children hospitalized due to COVID-19. The main goals were to see how long the drug stayed in their blood and to check for safety issues. The study was terminated early and only enrolled…
Matched conditions: COVID-19
Phase: PHASE1 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Stem cells tested in fight against COVID-19
Disease control TerminatedThis study tested whether infusions of stem cells from donor fat tissue could help patients with COVID-19. Researchers compared the stem cell treatment against a placebo (dummy infusion) in 48 adults suspected of having COVID-19. The main goals were to see if the treatment reduce…
Matched conditions: COVID-19
Phase: PHASE2 • Sponsor: Hope Biosciences Research Foundation • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Old drug tested as new hope against COVID-19
Disease control TerminatedThis study tested whether a low-dose oral medication called emetine could help treat COVID-19 symptoms and prevent severe outcomes like hospitalization. Researchers planned to give participants either emetine or a placebo pill for 10 days to compare results. The trial was termina…
Matched conditions: COVID-19
Phase: PHASE2, PHASE3 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Cancer drug tested in fight against COVID-19
Disease control TerminatedThis study tested whether adding the cancer drug imatinib to standard hospital care could help adults hospitalized with COVID-19. The goal was to see if the drug could reduce deaths by potentially blocking the virus and reducing severe lung inflammation. The trial was stopped ear…
Matched conditions: COVID-19
Phase: PHASE3 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Drug trial aims to calm deadly COVID-19 immune storm
Disease control TerminatedThis study tested whether a drug called tocilizumab could help adults hospitalized with severe COVID-19 pneumonia. The goal was to see if the drug, which calms an overactive immune system, could improve patients' health status and reduce the need for breathing support compared to…
Matched conditions: COVID-19
Phase: PHASE3 • Sponsor: Queen's Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Race for a COVID pill: hospital trial tests new antiviral
Disease control TerminatedThis study aimed to see if adding an experimental oral antiviral pill, called ensitrelvir, to standard hospital care could help adults hospitalized with COVID-19 recover faster and improve their chances of survival. The trial compared the pill to a placebo (a dummy pill) in over …
Matched conditions: COVID-19
Phase: PHASE3 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Early-Stop trial tests malaria drug for COVID-19
Disease control TerminatedThis study aimed to see if adding the drug hydroxychloroquine to standard hospital care helped adults with COVID-19 get better faster. It compared patients who received the drug for five days to those who received only usual care. The trial was stopped early after enrolling only …
Matched conditions: COVID-19
Phase: PHASE3 • Sponsor: Queen's Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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COVID drug trial halted after failing to show benefit
Disease control TerminatedThis study tested whether adding the drug ABX464 to standard COVID-19 care could reduce dangerous inflammation and prevent patients from developing severe breathing problems. It involved 509 adults aged 65+ or younger adults with risk factors like obesity or diabetes. The trial w…
Matched conditions: COVID-19
Phase: PHASE2, PHASE3 • Sponsor: Abivax S.A. • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Hospitalized COVID patients test Anti-Nausea shot
Disease control TerminatedThis study tested whether adding an injectable form of aprepitant—a medication normally used to prevent nausea—to standard hospital care could help adults recently hospitalized with COVID-19. Researchers wanted to see if it helped patients get discharged sooner and prevented them…
Matched conditions: COVID-19
Phase: PHASE2 • Sponsor: Heron Therapeutics • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Sniff your way to recovery? nasal spray tested for COVID-19
Disease control TerminatedThis study tested a nasal spray called AD17002 to see if it could help adults with mild to moderate COVID-19 get better faster. About 180 participants were randomly assigned to receive either a placebo or one of two doses of the spray, in addition to standard care. The main goals…
Matched conditions: COVID-19
Phase: PHASE2, PHASE3 • Sponsor: Advagene Biopharma Co. Ltd. • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Antibody shot tested in vulnerable kids to block COVID-19
Prevention TerminatedThis study tested a single shot of lab-made antibodies (casirivimab and imdevimab) to see if it could help prevent severe COVID-19 in high-risk children under 12. Researchers gave the shot to a small group of kids and tracked how long the drug stayed in their bodies and checked f…
Matched conditions: COVID-19
Phase: PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Prevention
Last updated Mar 30, 2026 14:33 UTC
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Could a daily pill shield frontline workers from COVID?
Prevention TerminatedThis study tested whether a daily pill (Emtricitabine/Tenofovir) could prevent COVID-19 in healthcare workers at high risk of exposure. Over 1,300 participants were randomly assigned to receive either the pill or a placebo, in addition to standard safety measures like masks. The …
Matched conditions: COVID-19
Phase: PHASE3 • Sponsor: Hospital Italiano de Buenos Aires • Aim: Prevention
Last updated Mar 23, 2026 15:15 UTC
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Can exercise rehab ease the lingering burden of long COVID?
Symptom relief TerminatedThis study aimed to see if a 10-week exercise and breathing rehabilitation program could help people with Long COVID. Researchers tested 21 participants to see if the program could reduce symptoms like fatigue and shortness of breath, improve physical fitness, and enhance mental …
Matched conditions: COVID-19
Phase: NA • Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Can video coaching help pharmacists overcome vaccine hesitancy?
Knowledge-focused TerminatedThis study tested whether giving rural pharmacists video coaching helps them better counsel patients who are hesitant about COVID-19 vaccines, compared to just giving them standard training materials. Researchers worked with 16 pharmacies in rural areas to see if the coaching imp…
Matched conditions: COVID-19
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC
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Study probes hidden COVID risk in vulnerable cancer patients
Knowledge-focused TerminatedThis study aimed to understand how COVID-19 affects people with cancer. Researchers screened 83 patients receiving cancer treatment to find out how many had the virus without showing symptoms. They also checked patients' blood to see how their immune systems responded to the infe…
Matched conditions: COVID-19
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Wristband tried to predict COVID breathing crises
Knowledge-focused TerminatedThis study tested a special wristband called the AirGo to monitor the breathing patterns of hospitalized COVID-19 patients who were breathing on their own. The goal was to see if the band could detect patterns that signal a patient's breathing is getting worse and might require a…
Matched conditions: COVID-19
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC