COVID - 19

This study tested a new mRNA vaccine designed to protect against COVID-19 in 182 healthy adults aged 18 and older. Researchers checked for side effects and measured the body's immune response after vaccination. The trial was stopped early, but the data helps understand the vaccin…

This study tested a single shot of two lab-made antibodies (casirivimab and imdevimab) in children under 12 who are at high risk for severe COVID-19. The goal was to measure how long the antibodies stay in the blood and check for side effects. Only 7 children took part before the…

This study aimed to see if hydroxychloroquine, a malaria drug, could help hospitalized COVID-19 patients recover faster. It planned to enroll 350 adults but was stopped early with only 17 participants. The trial compared those who got the drug plus usual care to those who got usu…

This study tested a single dose of two monoclonal antibodies (casirivimab+imdevimab) given intravenously to children hospitalized with COVID-19. The goal was to measure how the drug behaves in the body and check for side effects. Only 2 children were enrolled before the study was…

This study tested a nasal spray called AD17002 in adults aged 18 to 65 with mild to moderate COVID-19. Participants received standard care plus either a placebo or one of two doses of the spray. The goal was to see if the spray could help people feel better faster. The trial was …

This study tested whether imatinib, a cancer drug, could help hospitalized adults with COVID-19. The trial was stopped early after enrolling only 21 participants. The main goal was to see if imatinib reduced deaths by day 28, but the small size limits what can be concluded.

This study tested whether giving plasma (the liquid part of blood) from people who recovered from COVID-19 to hospitalized patients with moderate to severe COVID-19 could help them get better faster. The trial planned to enroll many participants but was stopped early after only 1…

This study tested whether the drug aprepitant could help hospitalized COVID-19 patients recover faster. The trial was stopped early after enrolling only 27 people. Researchers aimed to see if the drug reduced the need for breathing support or shortened hospital stays.

This study tested a medicine called ensovibep in adults with mild-to-moderate COVID-19 who were not hospitalized. The goal was to see if it could lower the amount of virus in the body and reduce the need for hospital or emergency care. The trial was stopped early, but the results…

This study tested whether tocilizumab, an anti-inflammatory drug, could help hospitalized adults with severe COVID-19. It aimed to compare the drug to a placebo in about 300 people, but was stopped early after enrolling only 20. The main goal was to see if patients improved on a …

This study tested whether a lower dose of the drug tocilizumab could help hospitalized COVID-19 patients with lung inflammation recover faster. The trial included 85 adults who were not on a breathing machine. Researchers compared two low doses (40mg and 120mg) to standard care, …

This study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes, high blood pressure, or obesity. The goal was to see if the drug could reduce deaths, need for intensive care, or heart complications. The tria…

This study tested whether stem cells from donated fat tissue could help people with COVID-19. Researchers gave 48 participants either the stem cells or a placebo through four IV infusions. The goal was to see if the treatment could lower inflammation and improve oxygen levels. Th…

This study tested an experimental drug called ABX464 in 509 adults aged 65 or older, or aged 18+ with risk factors like obesity or diabetes, who had COVID-19. The goal was to see if the drug could reduce inflammation and prevent severe breathing failure. However, the study was st…

This study tested an antiviral drug called ensitrelvir in 602 adults hospitalized with COVID-19. The goal was to see if adding this pill to standard care helped patients recover faster. The trial was terminated early, so final results are limited.

This study tested whether a daily pill (TAF/FTC), normally used for HIV, could prevent COVID-19 in healthcare workers at high risk of exposure. About 1,378 participants were randomly assigned to receive the drug or a placebo. The trial was terminated early, and the results did no…

This study looked at whether a 10-week exercise and lung rehabilitation program could help people with Long COVID feel better. Researchers measured changes in exercise ability, fatigue, and quality of life in 21 adults who had COVID at least 12 weeks earlier. The goal was to see …

This study tested whether a medicine called emetine could help adults aged 30 and older with mild to moderate COVID-19 feel better faster and avoid hospitalization. Participants took emetine or a placebo pill for 10 days. The trial was stopped early after only 4 people enrolled, …

This study aimed to understand how COVID-19 affects people with cancer. Researchers checked how many cancer patients had COVID-19 without symptoms and how their immune systems responded. The study included 83 patients but was stopped early.

This study tested a special band called AirGo that monitors breathing in COVID-19 patients with respiratory failure. Researchers wanted to see if the band could detect patterns of worsening breathing early. The study included 25 hospitalized adults with COVID-19 who were breathin…

This study looked at whether virtual coaching (like video calls) helps rural pharmacists better counsel people who are hesitant about getting the COVID-19 vaccine. Sixteen pharmacies took part, first using standard training and then adding a personal coach. The main goal was to s…

This study aimed to see how effective the 2024-2025 Pfizer COVID-19 vaccine is at preventing symptomatic COVID-19 in real-world settings. It planned to compare vaccinated and unvaccinated people who got tested at CVS MinuteClinics. However, the study was terminated early and only…