Real-World data on CPAP for COVID-19 respiratory failure

NCT ID NCT04307459

Completed Knowledge-focused Sponsor: University of Milan Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how well CPAP therapy works for COVID-19 patients who have trouble breathing. Researchers collected data from 250 patients in a hospital to see how they responded to treatment. The goal was to learn more about managing severe COVID-19 in real-life settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could provide valuable insights into the best use of CPAP therapy for COVID-19 patients with breathing problems.
What could go wrong: This is an observational study, not a controlled trial, so it cannot prove that CPAP therapy is effective. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome Coronavinae infectious disease Coronaviridae infectious disease COVID-19 respiratory failure severe acute respiratory syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONAVIRUS INFECTIONS RESPIRATORY FAILURE VENTILATOR LUNG

Contacts and locations

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Locations

Luigi Sacco University Hospital

Milan, Lombardy, 20157, Italy

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