AGING

This small, early-stage study tested whether drinking beetroot juice could improve blood flow to the brain and reduce artery stiffness in adults aged 50-79. Sixteen participants were randomly assigned to drink either regular beetroot juice or a version with the key ingredient rem…

This study tested if a combination of a supervised weight loss and exercise program plus the medication metformin could better improve physical function and reduce frailty in older veterans with obesity. It compared this combined approach to using just the lifestyle program or ju…

This large study tested whether a high-intensity rehabilitation program could help older adults recover better after being discharged from the hospital to a skilled nursing facility. It involved over 4,300 participants across 32 facilities, comparing the new rehab approach to usu…

This study tested whether taking a beta glucan supplement for 12 weeks could improve markers of biological age and immune system age in healthy adults over 40. Researchers measured changes in a panel of aging biomarkers in 60 participants who all took the supplement. The goal was…

This was a small, 9-month pilot study to see if two different diet approaches are practical for older adults who need to lose weight. Researchers tested whether people could stick to either eating fewer total calories or eating all their daily calories within a shorter time windo…

This study tested whether drinking a fermented milk containing a specific probiotic (Lactobacillus casei Shirota) daily could help slow muscle loss in older adults with sarcopenia. Researchers enrolled 132 elderly Taiwanese participants to see if the probiotic improved gut health…

This study tested whether getting hearing aid care through video calls (telehealth) works as well as going to a clinic for older adults who already use hearing aids. Researchers compared the two methods to see if telehealth helps people use their hearing aids more often and impro…

This study tested two different feedback methods to help emergency department doctors prescribe safer medications to veterans aged 65 and older. Researchers compared active coaching versus passive reports to see which approach better reduced prescriptions for medications that can…

This small pilot study tested whether adding protein from edible insects (mealworms) to cookies, combined with a supervised exercise program, could improve heart health in older adults. For 28 days, 30 participants aged 60+ ate either insect-based or regular cookies after exercis…

This study tested whether a 20-hour computer brain training program could help older adults with HIV who have thinking and memory problems. Researchers enrolled 119 participants, mostly from the Deep South, to see if the training was practical and could improve their mental sharp…

This study tested whether a simple, 4-week breathing exercise program could improve health in older men. Thirty healthy men aged 60-80 were split into two groups: one did the breathing training, and the other did not. Researchers measured if the exercises could strengthen breathi…

This study tested whether rapamycin, a drug used to prevent organ transplant rejection, could improve heart function in older adults. Researchers enrolled 20 healthy participants aged 70-95 and gave them rapamycin for 8 weeks. They used detailed heart MRI scans before and after t…

This study tested a lifestyle program called 'Fit Mind' to see if it could lower factors linked to Alzheimer's disease risk in older adults. The 8-session program included brain games, physical activity, nutrition tips, and social activities. Researchers compared changes in risk …

This study tested whether time-restricted eating (limiting daily food intake to a 10-hour window) could help prevent age-related memory decline in healthy older adults. For 6 months, 32 participants aged 55-80 followed this eating pattern. Researchers measured changes in brain bl…

This study tested whether a 14-day course of a dietary supplement called COMP-4 could improve blood vessel function in young, healthy adults. Researchers measured how well an artery in the arm could widen to increase blood flow and checked for changes in blood markers linked to c…

This study tested whether daily supplements made from chicken extract could help prevent cognitive decline in older adults who were not yet diagnosed with dementia. Over two years, 276 participants aged 55-75 either took the supplement, a related peptide, or a placebo. Researcher…

This study tested whether sending a dental professional to clean the teeth of older adults at home every three months could prevent painful root cavities. It involved 194 home-living seniors who needed help with daily care. The goal was to see if this regular cleaning, combined w…

This study tested whether a specially designed online video game and app could help adults age 45 and older improve their overall health and well-being. Researchers compared the game, which taught healthy habits and coping skills, against standard online health information. They …

This study tested a new gel called IPN-21-SENSE, which is injected to add volume to the cheeks and mid-face area. About 90 adults seeking to improve facial appearance were enrolled to see if the gel worked better than no treatment. Researchers measured changes in cheek volume and…

This small pilot study tested whether a group Nordic walking program could help older adults who were evacuated from their homes due to war. The program involved twice-weekly guided walks for two months, using special walking poles. Researchers wanted to see if this activity coul…

This study tested whether a gentle, non-drug therapy called acupressure could help older adults living in a nursing home. Researchers gave 50 participants either acupressure on specific points three times a week for a month or their usual care. They measured if the therapy improv…

This study tested whether a gardening program, called horticultural therapy, could help reduce feelings of loneliness and improve life satisfaction for older adults living in a nursing home. Researchers worked with 54 residents over 60 years old who did not have dementia. They co…

This study tested whether a 12-week adapted CrossFit program is better than usual activity for improving balance and strength in older adults. Researchers measured how quickly people could stand up, walk, and climb stairs, as well as their fear of falling. The goal was to see if …

This study tested whether a gentle, non-invasive brain stimulation technique (tDCS) could boost the benefits of computerized brain training games for older adults with recurring depression. Sixteen participants aged 60+ with depression and memory complaints were randomly assigned…

This study tested whether short bursts of intense exercise followed by rest periods could help older adults stay fit and independent. Thirty-nine adults over 60 participated in a supervised exercise program three times a week. The results showed improvements in strength, flexibil…

This study tested four different skin creams and serums to see if they could reduce wrinkles and improve the look of aging facial skin over eight weeks. It involved 132 healthy adults aged 40 to 65 with mild to moderate wrinkles. Researchers measured changes using special 3D imag…

This study tested whether a hyaluronic acid filler called STYLAGE® XXL is better than no treatment for adding volume to the mid-face area (cheeks). About 90 participants seeking cosmetic improvement were randomly assigned to receive the filler immediately or to wait 24 weeks. Res…

This study tested whether a breathing muscle training program could improve heart health and mood in postmenopausal women. Researchers worked with 28 women aged 50-75 to see if using a handheld breathing device for several weeks made a difference. The goal was to gather informati…

This study tested whether a friendly robot could help people with dementia or memory problems feel more socially connected and engaged. For three weeks, residents, their families, and staff in an assisted living community tried using a robot that led activities like trivia and ga…

This study tested whether a short, 4-week strength training program could improve health in healthy older men. Researchers looked at changes in breathing muscle thickness, liver fat levels, and quality of life. Thirty men aged 60-75 were split into a group that did the training a…

This study tested whether an 8-week program of social video calls could improve quality of life for older adults, including those with mild memory concerns. About 100 participants aged 65+ were randomly assigned to either start the video social groups immediately or wait 8 weeks.…

This study tested whether a 12-week group therapy program was practical and helpful for older adults living with HIV. Fifty participants were randomly assigned to either join the therapy groups or receive basic health information. The goal was to see if learning stress management…

This study tested whether watching exercise videos before doing the same exercises could help older adults more than just exercising alone. 162 people aged 65 and older were split into three groups: one did regular exercises, one watched videos first and then exercised, and one d…

This study tested whether taking a daily vitamin D supplement for 12 weeks could help older adults with obesity improve their muscle strength and physical function. Researchers gave 29 participants in southern Mexico a high daily dose of vitamin D and measured their grip strength…

This small pilot study tested whether eight home visits from a nurse could help older African American women manage chronic pain and depressive symptoms. The program, called DAPPER, combined counseling and practical support to help participants set personal goals for improving th…

This study tested whether a hyaluronic acid filler could improve the appearance of fine lines on the cheeks, a common sign of aging. Twenty participants received two filler injections and were followed for eight weeks. Doctors and patients rated the changes to see if the treatmen…

This study tested a 6-week program to help caregivers of people with dementia. Participants wore an Apple Watch to track their sleep and activity patterns and received weekly coaching calls. The goal was to help caregivers establish healthier daily routines to reduce symptoms of …

This study aimed to understand why being inactive after surgery or injury can harm blood vessels and muscles, especially in older adults. Researchers measured blood flow in the arms and legs of 14 participants to see how inactivity affects the body. The goal was to gather knowled…

This study aimed to understand how temporary pain affects a person's ability to learn and remember new walking patterns, especially in older adults. Researchers tested 61 healthy young and older adults, using mild electrical stimulation to create brief pain during a walking task.…

This study aimed to understand why older women who use cannabis have a higher risk of falling. Researchers compared how cannabis versus a placebo affected walking, balance, and thinking skills in 25 older women, some with HIV and some without. They tested participants under diffe…

This study aimed to understand how inflammation might affect feelings of pleasure and motivation in older adults, particularly those with anxiety. Researchers gave 40 participants aged 60-80 either a substance that causes temporary inflammation or a placebo, then measured their m…

This study aimed to understand why some women experience memory and thinking changes after menopause and how this might be linked to a higher risk of Alzheimer's disease later in life. Researchers studied 120 healthy postmenopausal women, using brain scans and memory tests to see…

This study aimed to understand how aging and body fat influence inflammation in the body. Researchers enrolled 100 veterans to see if a program combining moderate weight loss and aerobic exercise could reduce inflammation. The goal was to gather knowledge, not to provide a direct…

This study looked at how quickly taking a short break from regular exercise affects blood sugar control and blood vessel health in active older adults. Researchers compared 20 healthy, active older adults to younger adults by having them stop exercise for 3 days while monitoring …

This study aimed to measure how often older adults with diabetes living in long-term care facilities experience dangerously low blood sugar. Researchers used a continuous glucose monitor worn for 10 days on 86 residents to track these events. The goal was to gather better informa…

This study aimed to understand how the emotional skills of young women (45 or younger) with non-metastatic breast cancer and their partners affect how they adjust to the disease and its treatments. Researchers observed 391 couples to see how their emotional awareness and communic…

This study tested whether a specific blend of plant extracts (called LLP-01) could change levels of proteins in the blood related to inflammation and heart health. It involved 32 healthy adults aged 50-75 who took the supplement or a placebo for 60 days. Researchers measured bloo…

This study tested whether lowering heart rate with a medication called ivabradine could improve the flexibility and health of arteries in healthy people. It involved 30 healthy volunteers aged 25-65 who took either the drug or a placebo for 8 days. Researchers measured changes in…

This small, completed study aimed to understand if taking an L-Citrulline supplement could improve blood vessel health, particularly in the brain, for both young and older adults. Researchers measured changes in brain blood flow, eye vessel response, and other markers of vascular…

This study surveyed 47 adults aged 65 and older in France to understand how many use non-medical cannabidiol (CBD) and what they know about it. Researchers wanted to map out usage trends and identify potential knowledge gaps, especially regarding safety and drug interactions in a…

This study tested a new ultrasound method to measure natural brain pulsations. Researchers enrolled 53 healthy adults to see how these pulsations change as people get older. The goal was to understand normal brain aging, not to treat a disease.

This study aimed to understand how the COVID-19 pandemic and its restrictions impacted the health and well-being of people aged 75 and older, as well as their caregivers. Researchers followed over 1,000 older adults in Spain, analyzing their health records and conducting intervie…

This study examined how aging affects brain activity during anesthesia. Researchers recorded brain signals from 47 patients aged 19-82 during surgery to understand how older brains respond differently to anesthesia drugs. The goal is to improve anesthesia safety for elderly patie…

This study aimed to understand the link between poor night vision and the early stages of age-related macular degeneration (AMD), a common cause of vision loss in older adults. Researchers followed 556 participants, including older adults with and without early AMD and a younger …

This small pilot study tested whether eating different amounts of blueberry powder (equal to 1 or 2 cups of fresh blueberries) affects how older adults absorb healthy plant compounds and whether it changes markers of inflammation in their blood. Six older adults with mild depress…

This small pilot study aimed to gather initial information on how two different diets affect bone health and muscle function in older adults. Researchers compared a very low-carb ketogenic diet to a Mediterranean diet over six weeks in 12 participants. The goal was to collect ear…

This study explored whether daily breathing exercises, combined with brain training games, could influence markers of brain health and learning ability in healthy adults aged 50-70. For 12 weeks, 91 participants did daily online brain training and followed specific breathing rout…

This study explored whether a single session of exercise could improve how the brain responds to insulin in middle-aged and older adults. Researchers enrolled 16 participants aged 40-80 who were overweight and not regularly active. They measured brain blood flow and cognitive fun…

This study tested if wearing a special suit that simulates the physical limitations of old age could make healthcare workers more empathetic. 82 caregivers from nursing homes were split into two groups: one group wore the suit and had a lesson, while the other group only had the …

This study used brain scans (fMRI) to understand how normal aging changes the way people process emotional images. Researchers compared two groups—younger adults (20-35) and older adults (60-85)—while they viewed emotional scenes and made judgments about their feelings or potenti…

This study aimed to gather preliminary information about how a common breast cancer hormone therapy might affect the aging process. Researchers enrolled 94 women, primarily aged 65 and older, who were starting this standard treatment. They collected blood and stool samples and su…

This study aimed to understand how aging affects specific enzymes in the body that are needed to activate a common HIV prevention and treatment medication. Researchers collected blood and colon tissue samples from 21 adults of different ages, including people with HIV, people tak…

This study explored whether taking music improvisation classes could help improve self-regulation and thinking skills in older adults. Researchers enrolled 53 adults aged 60 and over, some with mild memory concerns and some without, to test the new training program. The goal was …

This study explored whether combining mental practice with a safe, mild form of brain stimulation could help people learn complex finger movements. It involved 64 healthy young and older adults who practiced a finger sequence in their minds while receiving either real or fake sti…

This study aimed to understand how a fiber supplement called inulin affects substances produced by gut bacteria in people with Chronic Obstructive Pulmonary Disease (COPD). Researchers compared 87 participants, including COPD patients and healthy adults, to see if fiber changed t…

This study investigated how heat waves affect older adults' hearts compared to younger people. Researchers exposed 59 healthy participants to simulated heat wave conditions to measure heart stress and body temperature changes. The goal was to better understand why elderly people …

This study aimed to understand why some older adults recover better than others after a major surgery like knee replacement. Researchers followed 297 people aged 60+ to measure their physical and mental recovery over time. The goal was to identify the biological and personal fact…

This study followed 81 stroke patients for up to 6 years to understand how damage to the brain's protective barrier relates to worsening brain changes seen on scans. Researchers used regular MRI scans with a special dye to track whether a 'leaky' blood-brain barrier predicts the …

This study aimed to understand why muscle loss speeds up in older adults with type 2 diabetes or after a hospital stay. Researchers studied 95 older adults to examine how the body processes nutrients for muscle building under these conditions. The goal was to identify new biologi…

This study aimed to see if simple, bedside tests could accurately predict heart and lung fitness in older adults. Researchers tested 64 people over age 65, comparing easy measures like handgrip strength and a step test with the complex, gold-standard fitness assessment. The goal …

This study aimed to design online mindfulness and healthy living programs for adults over 50 who are worried about their memory but still test normally. Researchers held focus groups with 23 participants to get their feedback on the program content and website design. The goal wa…

This study aimed to understand if a ketone supplement drink could improve how muscles work and use energy, particularly as people age. Researchers compared 25 healthy young and older men who took either the ketone drink or a placebo. They measured muscle performance, energy use, …

This study explored whether a safe, non-invasive brain stimulation technique could help older adults with walking difficulties learn and remember new walking skills, like stepping over obstacles. Researchers tested 72 older adults, using the stimulation during walking practice an…

This study aimed to understand how sleep quality is connected to balance and mental sharpness in healthy adults over 65. For six weeks, 18 participants wore a sleep-tracking ring and visited a lab weekly for balance and memory tests. The goal was to gather information to help dev…