Stroke study aims to unlock mystery of white matter brain changes
NCT ID NCT03366129
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study followed 81 adults who had stroke-like symptoms to see how damage to the blood-brain barrier relates to white matter changes in the brain. Over 6 years, participants had regular MRI scans and thinking tests. The goal was to better understand why some people develop mental decline after a stroke.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could help explain why some stroke patients develop thinking problems, pointing toward ways to prevent or slow that decline.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to any direct medical benefit, and results may not apply to all stroke patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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MedStar Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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Suburban Hospital - Johns Hopkins
Bethesda, Maryland, 20814, United States