Scientists track recovery in seniors after knee surgery to unlock secrets of resilience

NCT ID NCT04235309

Completed Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study from Duke University looked at 297 older adults (60+) undergoing knee replacement surgery. Researchers measured physical activity, pain, thinking skills, and immune responses before and after surgery to understand what helps people recover well. The goal was to find markers of physical resilience, not to test any treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which older patients will recover well after surgery and who might need extra support.
What could go wrong: This is an observational study, not a treatment trial. It only measures recovery patterns and cannot guarantee any direct benefit to participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING RESILIENCE

Contacts and locations

Locations

Duke Regional Hospital

Durham, North Carolina, 27704, United States
Duke University Hospital

Durham, North Carolina, 27710, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States

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