Cheek filler study shows promise for restoring youthful volume

NCT ID NCT05355454

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study tested a hyaluronic acid filler called STYLAGE® XXL against no treatment in 90 adults aged 30–65 who wanted to correct mid-face volume loss. Participants received injections in the cheek area, and researchers measured volume changes over 24 weeks. The goal was to see if the filler safely and effectively restores facial fullness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

STYLAGE® XXL (hyaluronic acid gel filler injected into the cheeks)

What this could lead to

If it works, this could provide a safe, non-surgical option to restore lost volume in the mid-face for a more youthful appearance.

What could go wrong

This is a small, completed study with 90 participants. Results may not apply to everyone, and fillers carry risks like swelling, bruising, or uneven results.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Medical Saint Jean

    Arras, France