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Brain scans reveal how aging changes emotional reactions

NCT ID NCT03969043

Knowledge-focused Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how the brain processes emotional images in healthy aging. Researchers used MRI scans to compare brain activity in younger adults (18-45) and older adults (60-85) while they judged emotions or imagined actions. The goal was to understand why older adults may focus more on positive than negative emotions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

May 2019

Finished

Dec 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant aged between 18 and 45 and between 60 and 85 years old * Visual acuity normal or corrected to normal * Affiliation to a social security scheme (copy of the vital card in support) * Signed informed consent * Medical examination before taking part in the MRI examination * Mini-Mental-State Examination Score (MMSE)\> 23/30 * Scale score of Beck depression ≤ 4 Exclusion Criteria: * Participant in other research protocols in progress with exclusion period * Unprotected Majors unable to express their consent * Protected Major (Persons mentioned in Articles L1121-5,6 and 8 of the Public Health Code) * Significant hearing or motor impairment * Neuropsychiatric or neurological pathology past or present (except benign epilepsy) * Taking narcotics and / or drugs for neurocognitive purposes * Existence of a severe condition in general (cardiac, respiratory, hematological, renal, hepatic, cancerous)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging

Contacts and locations

Locations

  • CHU Grenoble-Alpes

    Grenoble, France

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