University Hospital, Grenoble

This study collects information from 100 adults with high blood pressure who undergo a procedure called renal denervation, which uses radiofrequency or ultrasound to calm overactive kidney nerves. Researchers will measure blood pressure changes at home before and one year after t…

This study is testing a new, non-invasive way to detect Alzheimer's disease by looking for specific proteins (amyloid and tau) in stool samples. Researchers believe these proteins may travel from the brain to the gut, offering a simple diagnostic tool. The study will involve 115 …

This study tests whether specially trained nurses can diagnose and manage non-traumatic chest pain in the emergency department as effectively as doctors. About 182 adults with chest pain will be randomly assigned to either a nurse-led or standard doctor-led care. The goal is to s…

This study tests if a liquid sedative (midazolam) can reduce resistance to care in elderly patients with moderate to severe dementia who refuse help. Researchers will give the medicine before care tasks and measure changes in agitation and cooperation. The trial involves 30 hospi…

This early study tests if a procedure called arterial embolization, using a substance called Lipiodol, is safe for people with painful hand osteoarthritis that hasn't improved with standard treatments. Fifteen participants will receive the procedure and be monitored for 6 months …

This study tests whether a low dose of morphine can help people with severe COPD who need a breathing machine (non-invasive ventilation). The goal is to reduce early failure of the machine by easing pain, shortness of breath, and anxiety. About 24 adults with a COPD flare-up will…

This study tests whether giving a specific type of pain block (erector spinae plane block) early after a severe chest injury can reduce the number of days a patient needs a breathing machine. The trial will include 400 adults with three or more broken ribs from blunt chest trauma…

This study looks at a new way for family doctors to find early liver scarring (fibrosis) in people at risk, like those with diabetes or heavy alcohol use. About 150 adults who had a special liver scan will be followed to see if they get the right care afterward. The goal is to se…

This study follows 1,600 adults aged 60 and older who are hospitalized with respiratory infections like flu, COVID-19, or RSV. Researchers will measure changes in their ability to perform daily tasks, such as bathing and dressing, to understand how these infections lead to loss o…

This study looks at 30 patients who have had a Pseudomonas aeruginosa infection or carry the bacteria. The goal is to find and copy the antibodies their bodies made to fight it. These lab-made antibodies could one day offer a new way to treat infections that don't respond to anti…

This study is testing a new device that uses light to measure pulse waves and estimate blood pressure. Researchers want to see if this method is as reliable as current standard devices. The study involves 27 healthy adults and aims to improve how we monitor heart health without n…

This study is a practice run for future clinical trials. Researchers are testing brain and heart monitoring equipment on healthy volunteers, people with Parkinson's disease, and those with paralysis. The goal is to make sure the tests work well and are comfortable for participant…

This study looks at whether breathing low-oxygen air (hypoxic conditioning), either by itself or combined with exercise, can improve blood vessel health in the brains of older adults. Researchers will enroll 64 inactive people aged 60 to 80 to test this approach. The goal is to f…

This study asks adults with type 1 diabetes who use a closed-loop insulin pump how they feel about the special 'physical activity mode' designed to prevent low blood sugar during exercise. Up to 900 participants will fill out a questionnaire about their satisfaction and experienc…

This study looks at whether a type of scan called SPECT/CT can help doctors see if treatment is working in men with advanced prostate cancer. The treatment uses a radioactive drug (Lu-177 PSMA) that targets cancer cells. Researchers want to see if SPECT/CT, which is cheaper and m…

This study looks at how different types of anesthesia affect blood pressure stability during organ removal in brain-dead donors. About 270 donors will be randomly assigned to receive either a gas anesthetic, a painkiller, or no anesthetic at all. The goal is to find which approac…

This study looks at whether measuring carbon dioxide in a person's breath (EtCO2) can help doctors quickly tell how serious a COPD attack is. Researchers will monitor 240 adults who come to the emergency room with breathing trouble and a history of COPD. If successful, this simpl…