University Hospital, Grenoble

This study tests whether a brain implant can help people who had a stroke regain movement in their arm. Ten participants will first do standard rehab, then get the implant and use it to control devices during rehab for six months. The goal is to see if the implant is safe and hel…

This study compares two treatments for heavy bleeding after a miscarriage: a procedure that blocks blood vessels (embolization) alone, or that procedure followed by suctioning of the womb (aspiration). About 110 women will be followed for 12 months to see which approach stops ble…

This study looks at a new, thinner metal plate used to fix a common type of ankle fracture. Standard plates can cause skin problems or discomfort, sometimes needing a second surgery to remove them. The researchers want to see if this thinner plate helps bones heal with fewer skin…

This study tests a new way to detect prostate cancer early by looking at how suspicious spots on MRI change over time, rather than relying on a single scan. About 380 men with a suspicious MRI lesion will be followed to see if this approach reduces unnecessary biopsies and treatm…

This study looks at whether giving a higher dose of the blood thinner enoxaparin can better prevent dangerous blood clots in people with severe injuries. About 540 adults in intensive care after trauma will receive either the standard dose or a double dose. The goal is to see if …

This study looks at whether a special stress management program can help adults with myasthenia gravis feel less anxious and stressed, and improve their quality of life. About 62 participants will take part in the program and complete questionnaires. The goal is to see if this ap…

This study tests whether people with overactive bladder can be monitored at home after receiving botulinum toxin injections, instead of going to the hospital. About 112 adults will either do home check-ins or standard hospital visits. The goal is to see if home monitoring is just…

This study tests whether a non-invasive brain stimulation technique called tDCS can help manage pain in sedated patients in the intensive care unit (ICU). Forty adults on ventilators and receiving morphine will receive either real or fake tDCS sessions. Researchers will measure p…

This study looks at whether a special consultation before getting an implantable port (a small device placed under the skin for giving medications) can help cancer patients feel less anxious. About 150 adults who need a port for cancer treatment will be split into two groups: one…

This study tests if a gentle electrical current applied to the spine or nerves can reduce long-term pelvic pain. Sixty adults with pelvic pain for over a year will receive either real stimulation or a placebo (sham) treatment. Researchers will track pain levels using a simple 0-1…

This study looks at whether a digital app called LUSHA can help children aged 7-12 with ADHD and their parents. The app is designed as a game to motivate behavior change and improve parent-child interaction. Researchers will track how often families use the app over 3 months and …

This study looks at whether high-intensity interval training (short bursts of hard exercise) or moderate-intensity continuous training (steady cycling) works better to improve fitness and reduce frailty in adults aged 70 and older. About 92 participants will be followed as they e…

This study aims to find the best way to measure if a supervised exercise program helps people whose advanced lung cancer is stable on treatment. About 63 participants will join a 3-month rehab program. Researchers will check if it improves their strength, ability to stand up from…

This study uses ultrasound to see how non-invasive ventilation (a breathing mask) changes diaphragm movement in 20 people with ALS. Researchers will compare diaphragm motion with and without the ventilator. The goal is to better understand how the ventilator affects breathing mus…

This study looks at how doctors and nurses use a special solution (taurolidine) to keep PICC lines clean in patients who need nutrition through a vein. Researchers will check if the solution is given correctly and safely, and follow patients for 30 days after the line is placed. …

This study aims to understand why endometriosis develops and worsens by looking at immune cells and gut bacteria. Researchers will compare 40 women with and without endometriosis, collecting tissue, blood, and stool samples. The goal is to find new ways to treat this painful cond…

This study explores whether a blood test can identify the bacteria causing a brain abscess, potentially avoiding the need for risky brain surgery to get a sample. Researchers will compare the blood test results with standard lab tests on surgical samples from 15 adults. If succes…

This study looks at adults with obstructive sleep apnea whose CPAP therapy isn't working well. It tests whether a home monitoring device called Sunrise can guide treatment changes as effectively as an overnight lab sleep test. About 105 participants will try both methods to see i…

This study tests a new tool that uses famous monuments to see if people with Alzheimer's have more trouble naming and identifying them than healthy older adults. Researchers will compare 220 participants aged 50 and older. The goal is to develop a simple screening test for early …

This pilot study tests a new, faster MRI technique called MR fingerprinting for people who have had an ischemic stroke. Standard MRI scans take 20-25 minutes, but every minute counts in stroke care. The study will enroll 10 adults with a recent stroke to see if the new method can…

This study aims to better understand pain in people with arthrogryposis multiplex congenita (AMC) caused by a specific gene change (PIEZO2). Researchers will ask 12 participants aged 10 and older to rate their pain daily for two weeks and fill out questionnaires about quality of …

This study looks at whether melanoma patients who eat more fiber respond better to immunotherapy drugs. Researchers will track the fiber intake of 60 patients and see if those with a high-fiber diet have fewer recurrences or better tumor control. The goal is to understand the lin…

This study aims to improve how a device recognizes hand gestures by using a new computer algorithm. Ten healthy, right-handed adults will wear a muscle-signal sensor on their forearm and perform gestures. The researchers will compare the new algorithm's accuracy to standard metho…

This study looks at a protein called IL-1RAP found on abnormal cells in myelodysplastic syndromes (MDS), a pre-leukemic condition. Researchers will collect blood and bone marrow samples from 120 high-risk MDS patients to confirm IL-1RAP expression and test whether specially desig…

This study aims to better understand the symptoms of stricturing Crohn's disease by interviewing 15 adult patients. The goal is to identify which symptoms matter most to patients and how the disease affects daily life. This information will help create a more accurate clinical as…

This study looks at 100 kidney transplant patients to understand where the BK virus comes from and how the body fights it. Researchers want to find better ways to predict which patients are at risk for serious kidney damage. The goal is to improve monitoring and prevent complicat…

This study tracks 81 patients with early-stage, hormone-positive breast cancer who are prescribed a two- to three-year course of CDK4/6 inhibitor pills (abemaciclib or ribociclib) after surgery. The goal is to see how many stop taking the pills early and why. Researchers hope to …

This study looks at how premature babies learn to match what they see (lip movements) with what they hear (speech sounds). Researchers will track 60 infants born before 34 weeks to see when this skill develops compared to full-term babies. The goal is to find early signs of langu…

This study will use ultrasound to check for medial arterial calcification (hardening of the artery walls) in 60 healthy endurance athletes. The goal is to see how common this condition is in this group and whether it relates to their training habits or other heart risk factors. P…

This study tests whether measuring jaw movements can accurately assess breathing effort in ICU patients recovering from respiratory failure. Researchers will compare jaw movement signals to the standard invasive method (esophageal pressure) in 50 adults. If successful, this non-i…

This observational study aims to understand why some people with Parkinson's disease experience visual hallucinations. Researchers will compare how prior expectations influence false perceptions in patients with and without hallucinations, as well as healthy volunteers. Participa…