University Hospital, Grenoble

This study is looking at a new, thinner metal plate for fixing broken ankle bones. It aims to see if this plate causes fewer skin complications and less long-term discomfort than standard thicker plates, which could mean patients don't need a second surgery to have it removed. Th…

This study aims to see if eating a high-fiber diet helps melanoma patients respond better to their immunotherapy treatment. Researchers will observe 60 patients already receiving standard immunotherapy drugs and track their diet, health, and treatment outcomes. The goal is to lea…

This study tests whether a brain implant can help stroke survivors regain arm and hand movement. Ten participants will have a small device implanted in their brain that reads movement intentions, allowing them to control rehabilitation equipment with their thoughts. The goal is t…

This study aims to find the best type of exercise to improve heart and lung fitness in frail adults aged 70 and older. Researchers will compare two common exercise bike programs: short, intense bursts (HIIT) versus steady, moderate pedaling (MICT). The goal is to see which method…

This study aims to find the best way to treat dangerous bleeding that can happen after a miscarriage. Researchers will compare two procedures: one that blocks blood vessels alone, and another that combines that with a scraping of the uterus. They want to see if the simpler proced…

This study aims to understand why patients with early-stage, high-risk breast cancer stop taking their powerful new combination medications too soon. Researchers will follow 81 patients who are prescribed a standard hormone therapy pill plus a newer drug (like abemaciclib or ribo…

This study compares home monitoring to traditional hospital visits for patients receiving bladder injections to control overactive bladder. Researchers want to see if collecting bladder diaries and measurements at home works as well as coming to the hospital. The goal is to make …

This study aims to develop a new screening tool for Alzheimer's disease by testing whether people can identify and name famous monuments. Researchers will compare performance between 220 healthy elderly participants and people with Alzheimer's disease. The goal is to create a sim…

This study is testing whether a new blood test can accurately identify the germs causing brain abscesses (serious brain infections). Currently, doctors often need brain surgery to get a sample for testing, which isn't always possible. The research will compare results from the ne…

This study is testing a new, faster MRI technique called 'MRI Fingerprinting' to improve stroke diagnosis. Researchers want to see if this quicker method can provide clear enough images to replace current 20-25 minute scans. If successful, it could help doctors diagnose strokes f…

This study aims to see if tracking a patient's jaw movements can accurately measure how hard they are working to breathe, as an alternative to the current standard method which requires placing a tube down the throat. It will involve 50 adult ICU patients who are breathing on the…

This study is testing whether watching a suspicious prostate area with two MRI scans over time, instead of acting on just one scan, can help doctors make better decisions. The goal is to reduce unnecessary biopsies and the overtreatment of slow-growing cancers that may not need i…

This study aims to find the best way to measure if rehabilitation helps people with advanced lung cancer whose disease is stable after treatment. About 63 participants will join a 3-month physical activity program. Researchers will check if the program improves their quality of l…

This study is testing whether a digital game app called LUSHA is helpful for children with ADHD and their parents. 80 children aged 7-12 with an ADHD diagnosis will use the app for 3 months. Researchers want to see if families use the app regularly and if it helps improve the chi…

This study is testing whether a mild, painless electrical current applied to the skin can help reduce chronic pelvic pain. It will compare two different application sites (over the spine and over a nerve cluster) against a placebo treatment in 60 adults. The main goal is to see w…

This study is testing whether a gentle, non-drug brain stimulation technique can help reduce pain in sedated patients in intensive care. Researchers will compare real stimulation to a placebo in 40 patients to see if it lowers the need for strong painkillers like morphine. They w…

This study aims to better understand BK virus infections in kidney transplant patients. Researchers will observe 100 patients who already have the virus in their urine to learn where the virus comes from and how the body's immune system responds. The goal is to identify which pat…

This study aims to test a new computer algorithm designed to better recognize hand gestures from muscle signals. Researchers will compare their new method to existing ones to see which is more accurate and faster. The goal is to improve technology for future applications like adv…

This study aims to collect blood and bone marrow samples from people with myelodysplastic syndromes (MDS) to test a potential new immunotherapy. Researchers want to see if a lab-made immune cell therapy (CAR-T cells) can effectively target and kill MDS cells by recognizing a spec…

This international study aims to understand how a serious respiratory infection, like the flu or COVID-19, affects an older person's ability to live independently after a hospital stay. Researchers will follow 1,600 adults aged 60 and older who are hospitalized with a confirmed v…

This small, early-stage study aims to understand how a breathing support machine (non-invasive ventilation) affects the main breathing muscle (the diaphragm) in people with ALS. Researchers will use an ultrasound machine to take pictures of the diaphragm while patients breathe on…

This study aims to understand how premature babies learn to connect what they see (like lip movements) with what they hear (speech sounds), a key early step for language. Researchers will track 60 premature infants by measuring where they look when shown videos of people speaking…

This study aims to listen to patients with a specific form of Crohn's disease to understand their most important symptoms and how the disease affects their daily life. Researchers will conduct one-on-one interviews with 15 adults who have stricturing Crohn's disease. The goal is …

This study aims to understand how nurses currently use a special solution called taurolidine to lock and clean catheters (PICC lines) used for nutrition therapy. Researchers will observe 45 patients to see if the nurses' practices match the official instructions and recommendatio…

This study is testing a new way to understand the daily ups and downs of living with inflammatory arthritis, like rheumatoid arthritis. For two weeks, 50 participants will use a mobile app to report their pain, fatigue, and mood in real-time and wear a small activity tracker. The…

This study aims to understand how the immune system and gut bacteria are involved in endometriosis, a painful condition affecting many women. Researchers will compare tissue and stool samples from 40 women with endometriosis to samples from women without it. The goal is to find b…

This study aims to understand why some people with Parkinson's disease experience visual hallucinations. Researchers will have 60 participants, including Parkinson's patients with and without hallucinations, complete computer-based visual tasks and thinking tests. The goal is to …

This study aims to better understand the pain experienced by people with a rare genetic condition that causes stiff joints from birth (arthrogryposis). Researchers will remotely ask 12 participants, aged 10 and older, to track their pain levels and locations daily for two weeks. …

This study aims to find out how common a type of artery wall hardening is in healthy, long-distance endurance athletes. Researchers will use ultrasound scans on 60 athletes to check for this condition. The goal is to see if the amount or type of training is linked to this finding…