University Hospital, Grenoble

This early-phase study tested whether adding a new drug called NP137 to standard chemotherapy (mFOLFIRINOX) is safe for people with locally advanced pancreatic cancer that cannot be removed by surgery. The goal was to see if the combination could shrink tumors and help people liv…

This study looked at whether a drug called bosentan could lower blood pressure in people with sleep apnea and mild hypertension, as well as the standard CPAP machine does. Nineteen participants were given either bosentan or CPAP to compare effects on daytime and nighttime blood p…

This study tested a new, non-invasive imaging method to measure blood flow in the heart muscle. It involved 36 people with coronary artery disease who already needed a heart catheterization. The goal was to see if the new scan could give the same results as the standard invasive …

This study tested new light-based sensors that measure carbon dioxide and oxygen levels through the skin. Twenty healthy adults took part, and the new sensors were compared to standard lab tests. The goal was to see if these sensors work as well as current methods for monitoring …

This study tested a new, fast, and affordable COVID-19 test called TestNPass. Researchers checked how well it finds the virus using nose swabs from 400 adults. The goal was to see if it is accurate enough to use widely, helping people get results quickly without needing lab equip…

This study tested whether adding a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to standard rehabilitation exercises could help reduce pain in people with fibromyalgia. 42 adults with fibromyalgia were randomly assigned to re…

This pilot study tested whether a home-based, supervised exercise program is acceptable and safe for 36 women with anorexia nervosa. Participants were asked to complete 8 exercise sessions at home via video calls. The study measured how many people joined and finished the program…

This study tested whether using virtual reality (VR) in the waiting room could help lower anxiety in 156 adults about to have a heart catheterization. Patients wore a heart rate monitor and reported their anxiety levels. The goal was to see if VR could make the pre-procedure expe…

This study tested three different nerve stimulation techniques—two targeting the brain and one targeting the spine—to see which best reduces pain in people with algoneurodystrophy, a chronic pain condition. Thirty-six adults who had pain for over a year and did not respond to sta…

This study looked at how often obstructive sleep apnea (a condition where breathing stops and starts during sleep) occurs in adults with type 1 diabetes who use an insulin pump. Researchers measured sleep problems in 825 participants and checked for links to diabetes-related comp…

This study followed over 200 sleep apnea patients from a large European database to see what health problems they developed over time, such as heart issues, metabolic conditions, cancer, or death. Researchers also looked at whether using CPAP therapy (a common sleep apnea treatme…

This study used brain scans (fMRI) to understand how the hippocampus, a brain area known for memory, also helps with perception. Sixty healthy adults aged 18-35 performed tasks while their brain activity was recorded. The goal was to learn more about how the brain processes infor…

This study looked for early warning signs of sleep apnea in people with Down syndrome. Sleep apnea is common in this group but often missed, and it can harm the heart and brain. Researchers studied 40 adults with Down syndrome using sleep tests and heart monitoring to find factor…

This study tested a new questionnaire (the NF-scale) designed to measure sudden mood and thinking changes that can happen in Parkinson's disease. Researchers worked with 130 French-speaking adults who have Parkinson's and experience motor fluctuations. The goal was to confirm tha…

This study looked at whether a weight-loss program that includes nutrition and behavior changes can reduce the risk of sleep apnea in overweight and obese people. About 400 adults took part. Researchers measured sleep apnea risk and daytime sleepiness before and after the program…

This study looked at how the brains of younger (18-45) and older (60-85) adults process emotional images. Researchers used MRI scans to see which brain areas activate when people judge emotions or think about taking action. The goal was to understand normal changes in emotional p…

This study looked at how supplements that help the body make nitric oxide affect exercise in healthy, sedentary adults. Researchers measured muscle strength and blood flow after taking the supplements. The goal was to understand basic body responses, not to treat any illness.

This study tested a mobile app and a wearable activity tracker to see if they are practical for monitoring daily symptoms like pain, fatigue, mood, and sleep in people with inflammatory rheumatic diseases (such as rheumatoid arthritis and spondyloarthritis). Fifty adults used the…

This study looked at how two types of focal dystonia—cervical dystonia and blepharospasm—affect walking patterns. Researchers measured gait in 40 participants before and after treatment with botulinum toxin to see if the therapy changes how they walk. The goal was to better under…

This study looked at how long-distance trail running (40 to 160 km) affects muscle fatigue, heart function, sleep, and energy balance. Researchers measured muscle strength before and after races in 83 experienced runners. The goal was to better understand the physical stress of t…

This study tested a new decision-making guide for treating fractures of the hip socket (acetabulum). Researchers looked at results from 250 patients treated at a major trauma center. The goal was to see if the guide leads to better recovery and fewer hip replacements. This is an …

This study looked at whether teaching runners to use internal self-talk changes how hard they feel they are working during a trail run. 76 healthy adults aged 18-55 completed a treadmill test at a moderate pace. Researchers measured their perceived effort and psychological profil…

This study looked at 229 adults with rheumatoid arthritis, spondyloarthritis, or psoriatic arthritis to find out why they don't always follow their doctor's advice for managing other health problems. Researchers used questionnaires to identify barriers to following recommendation…

This completed French survey studied the burden of on-demand treatment for hereditary angioedema (HAE) attacks from the perspective of 300 patients and their caregivers. It collected information on attack frequency, severity, treatment delays, and impacts on quality of life, soci…

This study looked at how the COVID-19 lockdown affected weight, sleep, and mental health in nearly 4,800 adults who were already in a weight-loss program. Researchers wanted to see if stress, less exercise, and changes in eating habits during confinement slowed down weight loss. …

This study looked at how the brain reacts when people exercise in low-oxygen environments, like high altitudes. Thirty healthy men performed exercise while researchers measured brain activity and oxygen levels using special scans and brain stimulation. The goal was to understand …