University Hospital, Grenoble

This study looked at whether giving a sedative called propofol to very premature babies (under 32 weeks) before a less invasive breathing treatment (LISA) is safe and reduces the need for a breathing machine. The trial involved 233 infants with breathing problems. Researchers com…

This early-phase trial tested whether adding a new drug called NP137 to standard chemotherapy (mFOLFIRINOX) is safe and could help shrink tumors in people with locally advanced pancreatic cancer that cannot be removed by surgery. 43 participants received the combination. The main…

This study looked at 19 people with sleep apnea and mild high blood pressure. It compared a drug called bosentan to the standard CPAP machine to see if the drug could lower blood pressure just as well. The goal was to find a simpler way to manage heart risks in sleep apnea patien…

This study checked how well a new rapid test, TestNPass, can detect COVID-19 using a nose swab. It involved 400 adults at a hospital in France. The goal was to see if the test is accurate enough to replace slower PCR tests and provide a digital health pass.

This study tested new optical sensors that measure carbon dioxide and oxygen levels in the blood through the skin. Researchers compared these sensors to standard lab tests in 20 healthy adults. The goal was to see if the new sensors work as well as current methods.

This study tested a new, non-invasive imaging method to measure blood flow in the heart muscle. It involved 36 people with coronary artery disease who already needed a heart catheterization. The goal was to see if the new scan could give the same results as the standard invasive …

This pilot study tested whether a home-based, supervised exercise program is acceptable and safe for 36 women with anorexia nervosa. Participants were asked to complete 8 weekly exercise sessions at home. The study measured how many people joined and finished the program, their s…

This study tested whether using virtual reality (VR) in the waiting room could reduce anxiety in 156 adults about to undergo a heart catheterization. Participants used VR while waiting for their procedure, and researchers measured their stress levels using heart rate monitors and…

This study tested three types of non-invasive brain or spinal stimulation (tDCS, rTMS, and tsDCS) to see which best reduces pain in people with algoneurodystrophy, a chronic pain condition. 36 adults who had pain for over a year and didn't respond to drugs took part. The goal was…

This study tested whether adding a gentle brain stimulation technique called rTMS to standard exercise therapy could reduce pain in people with fibromyalgia. Forty-two adults with long-term pain took part, receiving either real or fake rTMS alongside exercise for 14 weeks. Resear…

This study looked at how sleep quality improves when people with obstructive sleep apnea start using a CPAP machine. Researchers used a special headband to track deep sleep at home for 7 nights before and 9 nights after starting treatment. The goal was to see how quickly sleep ge…

This study aimed to find blood markers that can predict whether the drug adalimumab will successfully treat ankylosing spondylitis after 6 months. Researchers analyzed blood samples from 50 adults starting adalimumab for the first time. The goal was to create an algorithm to help…

This completed French survey of 300 hereditary angioedema (HAE) patients and their caregivers aimed to understand the challenges of using on-demand treatments for HAE attacks. Researchers collected data on attack frequency, severity, treatment delays, hospitalizations, and the fi…

This study tested whether a smartphone app and a wearable activity tracker are practical and acceptable for people with inflammatory rheumatic diseases like rheumatoid arthritis and spondyloarthritis. Over 14 days, 50 participants answered short surveys on their phone and wore a …

This study tested a new decision-making guide for treating fractures of the hip socket (acetabulum). Researchers at Grenoble University Hospital reviewed the results of 250 adult patients treated using this guide. The goal was to see if the guide leads to better recovery and fewe…

This study tested whether teaching trail runners to use internal self-talk (like motivational phrases) changes how hard they feel running is. 76 adults completed a videoconference session on mental strategies or a control session, then ran on a treadmill. Researchers measured the…

This completed study with 40 participants explored factors that might predict obstructive sleep apnea in people with Down syndrome. Researchers used a range of assessments, including sleep studies, heart monitoring, and exercise tests, to identify early warning signs. The goal is…

This study looked at how extreme trail running—races from 40 to 160 km—affects the body. Researchers measured muscle fatigue, heart function, blood sugar, body composition, and sleep in 83 experienced runners before and after races. The goal was to better understand the physical …

This study looked at how certain dietary supplements (nitrate, L-Arginine, L-Citrulline) affect exercise performance in 63 healthy, sedentary adults. Participants took the supplements or a placebo for up to 8 weeks. Researchers measured muscle strength and blood flow after exerci…

This study looked at whether a nutrition and behavior change program could help reduce sleep apnea in people who are overweight or obese. About 400 adults took part, and researchers measured changes in sleep apnea risk, daytime sleepiness, and weight loss. The goal was to see if …

This completed study looked at 825 adults with type 1 diabetes who use an insulin pump to see how many also have obstructive sleep apnea. Researchers used overnight oxygen tests and sleep studies to find cases. The goal was to understand if sleep apnea is linked to diabetes compl…

This study looked at how COVID-19 lockdowns changed weight, sleep, and behavior in nearly 4,800 adults already in a weight-loss program in France. Researchers wanted to see if stress, less exercise, and changes in eating habits during confinement slowed weight loss. The study is …

This completed study surveyed 229 people with chronic inflammatory rheumatism (like rheumatoid arthritis) and their doctors to find out what makes it hard to follow care recommendations after a hospital visit. The goal was to identify barriers to good outpatient management. No tr…

This study tested a new questionnaire called the NF-scale, designed to measure sudden mood and thinking changes (neuropsychiatric fluctuations) that can occur in Parkinson disease. 130 French-speaking participants with Parkinson disease and motor fluctuations filled out the quest…

This completed study used MRI scans to watch brain activity in 60 healthy young adults while they performed memory and perception tasks. Researchers focused on the hippocampus, a brain area traditionally linked to memory, to test whether it also handles non-memory tasks like reco…

This study followed over 200 sleep apnea patients from a large European database to see how many developed heart problems, metabolic issues, cancer, or died over time. Researchers also checked whether using CPAP therapy (a common sleep apnea treatment) affected these risks. The g…

This study looked at how the brain processes emotional images in healthy aging. Researchers used MRI scans to compare brain activity in younger adults (18-45) and older adults (60-85) while they judged emotions or imagined actions. The goal was to understand why older adults may …

This study looked at how the brain responds when people exercise while breathing low-oxygen air (like at high altitude). Thirty healthy men did exercise tests while researchers measured brain and muscle activity using special scans and stimulation. The goal was to understand why …

This study looked at how cervical dystonia (neck muscle spasms) and blepharospasm (eye muscle spasms) affect walking. Researchers measured gait in 40 participants before and after botulinum toxin treatment to see if it improves walking patterns. The goal was to better understand …