New hope for pancreatic cancer: drug combo shows promise in early trial

NCT ID NCT05546853

First seen Feb 06, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This early-phase study tested whether adding a new drug called NP137 to standard chemotherapy (mFOLFIRINOX) is safe for people with locally advanced pancreatic cancer that cannot be removed by surgery. The goal was to see if the combination could shrink tumors and help people live longer. The trial involved 43 adults aged 18 to 79 with this type of cancer.

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Contacts and locations

Locations

  • AP-HP Pitié Salpetrière

    Paris, 75013, France

  • CHRU Lille

    Lille, 59037, France

  • CHU Poitiers

    Poitiers, 86000, France

  • CHU Rennes

    Rennes, 35033, France

  • CHU St Etienne

    Saint-Etienne, 42055, France

  • CHU de BORDEAUX

    Bordeaux, Bordeaux, 33404, France

  • CHU de GRENOBLE ALPES

    Grenoble, Alpes, 38043, France

  • CHU de REIMS

    Reims, Reims, 51092, France

  • Hôpital Privé Jean Mermoz

    Lyon, 69008, France

Conditions

Explore the condition pages connected to this study.