New tool aims to catch Parkinson's hidden mood swings

NCT ID NCT04455074

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new questionnaire called the NF-scale, designed to measure sudden mood and thinking changes (neuropsychiatric fluctuations) that can occur in Parkinson disease. 130 French-speaking participants with Parkinson disease and motor fluctuations filled out the questionnaire during both their OFF and ON medication states. The goal was to see if the scale is reliable and accurate for use in clinics and research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If validated, this scale could help doctors better detect and manage mood and thinking fluctuations in Parkinson disease, improving patient care.

What could go wrong

This is a validation study, not a treatment trial. The scale may not prove reliable or useful in routine practice, and results may not apply to non-French speakers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHRU Strasbourg

    Strasbourg, 67091, France

  • CHU Amiens

    Amiens, 80 054, France

  • CHU Clermont-Ferrand

    Clermont-Ferrand, 63003, France

  • CHU de Bordeaux-Hôpital Pellegrin

    Bordeaux, 33 076, France

  • Hospices Civils Lyon (HCL)

    Lyon, 69 677, France

  • University hospital grenoble

    Grenoble, 38043, France