New tool aims to catch Parkinson's hidden mood swings

NCT ID NCT04455074

Completed Knowledge-focused Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new questionnaire called the NF-scale, designed to measure sudden mood and thinking changes (neuropsychiatric fluctuations) that can occur in Parkinson disease. 130 French-speaking participants with Parkinson disease and motor fluctuations filled out the questionnaire during both their OFF and ON medication states. The goal was to see if the scale is reliable and accurate for use in clinics and research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If validated, this scale could help doctors better detect and manage mood and thinking fluctuations in Parkinson disease, improving patient care.
What could go wrong: This is a validation study, not a treatment trial. The scale may not prove reliable or useful in routine practice, and results may not apply to non-French speakers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FLUCTUATING MOOD SYMPTOMS PARKINSON DISEASE

Contacts and locations

Locations

CHRU Strasbourg

Strasbourg, 67091, France
CHU Amiens

Amiens, 80 054, France
CHU Clermont-Ferrand

Clermont-Ferrand, 63003, France
CHU de Bordeaux-Hôpital Pellegrin

Bordeaux, 33 076, France
Hospices Civils Lyon (HCL)

Lyon, 69 677, France
University hospital grenoble

Grenoble, 38043, France

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