Can ultrasound reveal how breathing machines affect ALS Patients' diaphragms?

NCT ID NCT07170865

Not yet recruiting Knowledge-focused Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This pilot study will use ultrasound to measure diaphragm movement in 20 ALS patients, both while they breathe on their own and while using non-invasive ventilation (NIV). The goal is to see if ultrasound can detect changes in how the diaphragm works with and without the breathing support. This is an observational study, meaning no new treatment is being tested—just a new way of measuring an existing therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better monitor diaphragm function in ALS patients using ultrasound, potentially improving how and when non-invasive ventilation is used.
What could go wrong: This is a very small pilot study with only 20 people. It is observational, not testing a treatment, so it cannot directly change patient care. Results may not apply to all ALS patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS (ALS) NON INVASIVE VENTILATION (NIV)

Contacts and locations

Locations

CHU Grenoble-Alpes

Grenoble, Isère, 38043, France

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