Tiny Lab-Grown organs reveal secrets of rare gut disorder
NCT ID NCT06687564
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how certain changes in the ACTG2 gene affect the development and function of intestinal muscle in children with a rare condition called pediatric intestinal pseudo-obstruction (PIPO). Researchers will take cells from 4 patients with PIPO and grow them into mini-intestines (organoids) in the lab to compare with healthy samples. The goal is to understand the gene's role, not to test a treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AP-HP Hôpital Robert Debré
RECRUITINGParis, 75019, France
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Phymedexp Inserm U1046 - Cnrs Umr 9214
RECRUITINGMontpellier, 34295, France
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Tens - Inserm Un Umr 1235
RECRUITINGNantes, 44035, France