Tiny Lab-Grown organs reveal secrets of rare gut disorder

NCT ID NCT06687564

Recruiting now Knowledge-focused Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how certain changes in the ACTG2 gene affect the development and function of intestinal muscle in children with a rare condition called pediatric intestinal pseudo-obstruction (PIPO). Researchers will take cells from 4 patients with PIPO and grow them into mini-intestines (organoids) in the lab to compare with healthy samples. The goal is to understand the gene's role, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

intestinal pseudo-obstruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PIPO

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AP-HP Hôpital Robert Debré
RECRUITING

Paris, 75019, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Phymedexp Inserm U1046 - Cnrs Umr 9214
RECRUITING

Montpellier, 34295, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Tens - Inserm Un Umr 1235
RECRUITING

Nantes, 44035, France

Contact Phone: •••-•••-•••• Email: •••••@•••••