Cheek filler gel shows promise in clinical trial
NCT ID NCT05747456
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a new gel called IPN-21-SENSE, made from hyaluronic acid, to restore lost volume in the mid-face (cheeks). 89 adults aged 30-84 who wanted cheek volume correction were randomly assigned to get the gel or no treatment. The gel was injected into the cheek area, with an optional touch-up. The main goal was to see if the gel improved cheek volume more than no treatment after 24 weeks. Results showed it worked better than doing nothing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hyaluronic acid gel (IPN-21-SENSE)
What this could lead to
If it works, this could offer a safe, effective option for restoring lost volume in the cheeks without surgery.
What could go wrong
This is a small, completed trial with no long-term safety data beyond 24 weeks. Results may not apply to everyone, and risks like swelling or bruising are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Eurofins Dermscan
Villeurbanne, France