Cheek filler gel shows promise in clinical trial

NCT ID NCT05747456

Completed Symptom relief Sponsor: Laboratoires Vivacy Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a new gel called IPN-21-SENSE, made from hyaluronic acid, to restore lost volume in the mid-face (cheeks). 89 adults aged 30-84 who wanted cheek volume correction were randomly assigned to get the gel or no treatment. The gel was injected into the cheek area, with an optional touch-up. The main goal was to see if the gel improved cheek volume more than no treatment after 24 weeks. Results showed it worked better than doing nothing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hyaluronic acid gel (IPN-21-SENSE)
What this could lead to: If it works, this could offer a safe, effective option for restoring lost volume in the cheeks without surgery.
What could go wrong: This is a small, completed trial with no long-term safety data beyond 24 weeks. Results may not apply to everyone, and risks like swelling or bruising are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AESTHETICS AGING VOLUME DEFICIENCY IN THE MID-FACE

Contacts and locations

Locations

Eurofins Dermscan

Villeurbanne, France

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