Simple creams might fight aging inflammation

NCT ID NCT06750653

Completed Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This pilot study tests whether applying over-the-counter moisturizers (CeraVe or Vaseline) daily for 4 weeks can reduce inflammation in adults aged 70 and older with dry skin. Researchers will measure skin barrier function, blood markers of inflammation, and skin microbes. The main goal is to see if a larger trial is possible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CeraVe Moisturizing Cream or Vaseline petroleum jelly
What this could lead to: If successful, this could show that simple moisturizers help lower inflammation in older adults, pointing toward a low-cost way to improve health.
What could go wrong: This is a very small pilot study (32 people) focused on feasibility, not proof of benefit. Results may not apply broadly, and any anti-inflammatory effect may be minimal.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dermatitis Inflammation inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING INFLAMMATION SKIN INFLAMMATION

Contacts and locations

Locations

UCSF

San Francisco, California, 94115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.