Metformin's Anti-Aging effects may depend on your insulin sensitivity
NCT ID NCT04264897
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study looked at whether the diabetes drug metformin can slow aging in people without diabetes. Researchers wanted to see if the drug's effects depend on whether a person is insulin sensitive or insulin resistant. Over 12 weeks, 101 adults aged 40-75 took either metformin or a placebo, and their insulin sensitivity, blood sugar, and muscle cell function were measured. The goal was to understand who might benefit most from metformin as an anti-aging treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Oklahoma Health Sciences Center, Oklahoma Shared Clinical and Translational Resources
Oklahoma City, Oklahoma, 73104, United States
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University of Wisconsin-Madison
Madison, Wisconsin, 53705, United States
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