Sohag University

This study aims to find the safest and most effective dose of a drug called protamine, which is used to reverse blood thinners after heart surgery using a heart-lung machine. Researchers will compare three different dosing strategies in 195 adults having planned heart surgery. Th…

This study will observe 300 patients with non-metastatic bladder cancer who receive high-dose radiation therapy aimed at curing their cancer, with or without chemotherapy. Researchers will track how long patients survive, whether the cancer returns in the bladder, and what side e…

This study is testing if a modified Atkins diet, a high-fat, low-carb eating plan, can help children whose epilepsy doesn't respond to medication. It will measure if the diet reduces how often and how long seizures last, and if it improves the child's thinking skills and overall …

This study aims to find out which of two common surgical techniques works better for repairing certain ankle fractures. Doctors will compare using a metal plate and screws on the outside of the bone versus placing a single screw inside the bone's canal. They will measure which me…

This study will test whether SGLT2 inhibitor drugs, typically used for diabetes, can help improve anemia in people with chronic kidney disease. Researchers will measure changes in hemoglobin levels in 60 adult participants with stable anemia. The goal is to see if these medicatio…

This study aims to see if teaching university students with type 1 diabetes how to count carbohydrates in their food helps them better control their blood sugar. Researchers will give 100 students at Sohag University a lesson on carb counting and provide educational booklets. The…

This study aims to find out which of two injections works better when given during a hair transplant to help the new hair grow. Researchers will compare Platelet-Rich Plasma (PRP) and Nanofat in 30 men with male pattern baldness. They will measure hair density and thickness after…

This study compares two types of minimally invasive spine surgery for people with a herniated disc in their lower back. It will look at which technique—using one small portal or two—leads to better pain relief, faster recovery, and fewer complications. The goal is to help surgeon…

This study is testing whether adding a 5% salt water (sodium chloride) solution to standard antibiotic eye drops helps people with bacterial eye infections heal faster. Researchers will compare two groups: one using antibiotics plus the salt water drops, and another using antibio…

This study aims to measure the hearing results of a specific type of ear surgery for otosclerosis, a condition where a tiny bone in the ear stiffens and causes hearing loss. It will involve 30 patients who have this condition and are scheduled for the surgery. The researchers wil…

This study compares two common anesthesia methods (propofol vs. sevoflurane) during a specific eye surgery for cataract patients. Researchers want to see which anesthesia better controls eye pressure and keeps heart rate and blood pressure stable during the procedure. The goal is…

This study is testing a three-part treatment for people severely poisoned by aluminum phosphide, a toxic insecticide often called 'rice tablets.' The treatment combines an infusion to support the heart and metabolism, a steroid to fight shock, and a repurposed pill that may direc…

This study aims to find the best laser setting to safely reduce swelling in the back of the eye (macular edema) caused by diabetes. It will compare two different laser pulse patterns in 50 adults with this condition. The goal is to control the disease and protect vision by findin…

This study is testing a specific surgical technique to treat a rare birth defect where the two bones in the forearm are fused together, limiting arm rotation. The surgery involves cutting and repositioning the bones, then holding them with wires. The goal is to restore the abilit…

This study aims to see how well MRI scans can tell the difference between harmless and potentially cancerous ovarian cysts. It will involve 50 women whose ultrasound results were unclear. Researchers will compare the MRI findings to results from surgery or follow-up tests to see …

This study aims to find out if measuring a protein called irisin in the blood can help doctors detect diabetic kidney disease earlier and track its progression. Researchers will compare irisin levels in 200 people with type 2 diabetes to see if they correlate with kidney health. …

This study aims to see how accurate a specific ultrasound finding, called the 'rail sign,' is at detecting a condition called placenta accreta. Placenta accreta is a serious complication where the placenta grows too deeply into the uterine wall, which can cause severe bleeding du…

This study aims to see if tracking a simple blood marker (the Systemic Immune Inflammation Index or SII) over time can help doctors detect and predict serious kidney injury in hospitalized patients with liver cirrhosis. Researchers will enroll 100 adults with liver cirrhosis to s…

This study aims to see if a special type of MRI scan can accurately tell the difference between harmless and cancerous growths in the uterus. Researchers will compare the scan results from 30 women with suspected uterine issues to their actual biopsy or surgery results. The goal …

This study aims to see how well a specific set of brain function tests can spot early, subtle thinking problems in people with stable liver cirrhosis. Researchers will compare test results from 150 cirrhosis patients to those of healthy volunteers. The goal is to find a reliable …

This study aims to find a better way to tell apart two similar conditions that cause low platelets and bleeding risk: primary immune thrombocytopenia (ITP) and low platelets caused by lupus (SLE). Researchers will test blood samples from 300 adults to see if measuring levels of t…

This study aims to see how accurately a simple stool test can detect colon cancer and precancerous growths. Researchers will compare the test results from 150 adults with findings from their routine colonoscopies. The goal is to understand if this non-invasive test can reliably i…

This study aims to find out whether MRI or ultrasound is more accurate at telling if a soft tissue lump near the skin's surface is harmless or cancerous. Researchers will scan 50 patients with these lumps using both imaging methods and compare the results. The goal is to improve …

This study compares two different office-based procedures for treating carpal tunnel syndrome. Researchers will test whether ultrasound-guided pulsed radiofrequency or an enzyme injection called hyaluronidase works better to relieve pain and improve hand function. The study will …

This study compares two methods of numbing nerves during shoulder surgery. Researchers want to see if combining two specific nerve blocks reduces breathing problems that sometimes occur with the standard approach, while still providing good pain relief. The study will involve 60 …

This study aims to find which of three common drugs works best to quickly stop shivering that sometimes happens after spinal anesthesia. Researchers will compare magnesium sulphate, ondansetron, and dexmedetomidine in 60 adults having planned lower body surgery. They will measure…

This study is testing two different ways of using pulsed radiofrequency energy to treat severe facial nerve pain (trigeminal neuralgia). Researchers will compare a newer, more evenly distributed energy pattern against the standard method to see which works better and is safer. Th…

This study aims to see if a newer type of pulsed radiofrequency treatment works better than the standard type for reducing long-lasting nerve pain after shingles (postherpetic neuralgia). It will enroll 100 adults whose pain has lasted over a month and hasn't responded well to us…

This study aims to see if a daily saline-glycerin enema can help children with fecal incontinence have more days without accidents. It will involve about 30 children aged 3 to 16 who have this condition due to various causes like past surgeries or nerve problems. The main goal is…

This study compares two surgical techniques for repairing a common finger joint injury. Researchers want to see if using a small internal anchor leads to better recovery than the traditional external pull-out suture method. The study will involve 12 adults with recent finger inju…

This study aims to see if a skin treatment called microneedling works better for new, red stretch marks when combined with one of two creams (tretinoin or timolol). Researchers will enroll 300 adults to test which combination is most effective at improving the skin's appearance. …

This study aims to see which of two inhaled medications works better to prevent sore throat after surgery when a breathing tube is used. Researchers will compare ketamine and magnesium sulfate, both given as a mist before surgery, in 150 adult patients. The goal is to find which …

This study aims to understand how common drug-resistant tuberculosis (TB) is in Egypt and to identify which patients are most at risk. Researchers will analyze samples from 250 patients who have already tested positive for TB using two advanced laboratory tests. The goal is to ga…

This study aims to understand how regular blood transfusions for beta thalassemia might affect hormone and reproductive development in boys. Researchers will measure several key hormones in 80 boys aged 10 to 18 with the condition. The goal is to detect any early abnormalities to…

This study aims to understand the role of a specific gene change, called a Notch1 mutation, in two types of blood cancer: Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin's Lymphoma (NHL). Researchers will test blood and bone marrow samples from 80 patients to see how often thi…

This is a laboratory study, not a treatment trial. Researchers will collect bacteria samples from 100 patients infected with a dangerous, hard-to-treat strain of Klebsiella pneumoniae. They aim to understand why some of these bacteria are resistant to the antibiotic cefiderocol, …

This study aims to understand breastfeeding practices, knowledge, and confidence among mothers in Sohag Governorate, Egypt. Researchers will survey 380 mothers with children up to 2 years old. The goal is to gather information on how many mothers breastfeed exclusively and what f…

This study aims to understand if the amount of Omega-6 fats in a person's blood is connected to having liver cancer. Researchers will compare blood samples from 100 adults with liver cancer to samples from healthy people of similar age and gender. The goal is to gather informatio…

This study aims to understand how breast cancer changes when it returns after initial treatment. Researchers will look back at medical records of 200 patients treated between 2015 and 2025 to compare the cancer's biology at diagnosis versus at recurrence. The goal is to learn if …

This study aims to understand the differences between psychosis caused by methamphetamine use and schizophrenia. Researchers will follow 200 adults in Egypt who have either condition, tracking their symptoms and recovery over three months. The goal is to see if these two types of…

This study aims to find out if a common blood test result, called mean platelet volume (MPV), can help predict which people with fatty liver disease are at high risk for a heart attack. Researchers will compare MPV levels in 60 patients with fatty liver disease, some who have had…

This study aims to understand if having different types of anemia causes the HbA1c blood test—commonly used to screen for diabetes—to give falsely high or low readings in people who do not have diabetes. Researchers will compare test results from 100 non-diabetic adults with vari…

This study aims to understand patterns, outcomes, and predictors of injury severity in children under 18 who experience trauma. Researchers will analyze registry data from two Egyptian university hospitals over six months, tracking which children need intensive care and how long …

This study aims to understand if there is a connection between dry eye disease and diabetic macular edema in people with long-term diabetes. Researchers will examine 50 adult patients with diabetes to measure their dry eye symptoms and check for swelling in the back of the eye. T…

This study aims to understand how lupus that starts with unusual symptoms differs from more common forms of the disease. Researchers will compare 400 patients with typical and atypical lupus presentations to see if one group has more severe disease activity or accumulates more pe…

This study will review medical records of 100 patients with locally advanced rectal cancer treated in Egypt between 2018 and 2025. Researchers will analyze which treatment approaches were used and how patients fared in terms of survival, cancer response, and side effects. The goa…

This study aims to better understand rheumatoid arthritis by measuring specific markers in the blood. Researchers will compare levels of a gene (CCR6) and a protein (CCL20) in 60 adults with RA against healthy individuals. The goal is to see if these markers can help explain the …

This study aims to find out if simple ratios calculated from a standard blood test (comparing certain white blood cell counts to a protein called albumin) can help doctors predict how severe a stroke will be and how well a patient might recover. Researchers will follow 60 adults …

This study aims to understand how rare, inherited immune disorders affect children's quality of life. Researchers will survey 50 children with these conditions and compare their answers to healthy children. The goal is to identify the main factors that make daily life harder for …

This study aims to carefully document the specific structural problems inside the nose that surgeons encounter during cosmetic and functional nose surgery (septorhinoplasty). Researchers will observe 25 patients aged 16-60 who are scheduled for this surgery, excluding those with …

This study aims to better understand sigmoid colon volvulus, a condition where part of the large intestine twists and causes blockage. Researchers will observe 40 patients in Sohag, Egypt, to see how often this occurs in younger people, not just the elderly. The goal is to help d…

This study aims to find patterns that predict when rheumatoid arthritis symptoms will suddenly worsen (flare). Researchers will follow 200 patients whose arthritis is currently controlled, checking them every 3 months. They will analyze patients' health data and simple blood test…

This study aims to better understand ankylosing spondylitis, a type of inflammatory arthritis that primarily affects the spine. Researchers will measure levels of specific immune system proteins (IL-17, IL-38, IL-41) and a genetic marker (HLA-B27) in the blood of 84 people—half w…

This study aims to understand how diabetes-related metabolic problems affect hospital outcomes for people with chronic kidney disease. Researchers will collect existing medical information from 200 hospitalized patients to see if certain lab results are linked to serious events l…

This study aims to test how well a specific prediction tool works for pregnant women with preeclampsia in Egypt. The tool, called fullPIERS, uses simple information like blood tests and pregnancy week to estimate a woman's risk of serious complications. Researchers will enroll 50…

This study aims to understand how two common types of local anesthesia used for cataract surgery affect the tiny blood vessels in the back of the eye. Researchers will use a special imaging scan (OCT angiography) to measure blood vessel density in the retina before and after the …

This study aims to understand how chemotherapy affects thinking skills, memory, and emotional well-being in women with breast cancer. Researchers will follow 100 newly diagnosed patients in Egypt, assessing them before starting treatment and again one year after finishing. The go…

This study aims to understand if certain fats in the blood are linked to acne. Researchers will compare blood samples from 80 people, half with acne and half without, to measure levels of three specific fat molecules. The goal is to learn more about what causes acne, which could …

This study aims to understand if simple blood tests can help predict serious complications for mothers and babies affected by HELLP syndrome, a severe pregnancy disorder. Researchers will observe 60 pregnant women with HELLP syndrome, measuring specific markers in their blood rel…

This study aims to understand how well the antibiotic ceftazidime-avibactam works against a dangerous, drug-resistant bacteria called Klebsiella pneumoniae. Researchers will collect samples from 100 hospital patients with infections and test the bacteria in the lab. The main goal…

This study aims to see if a new, non-invasive eye scan can detect early signs of vision damage in patients who have been taking hydroxychloroquine for at least one year. Hydroxychloroquine is a common medication for autoimmune diseases but can harm the retina over time. Researche…

This study aims to see if a simple calculation using heart rate and blood pressure, called the Modified Shock Index, can help doctors better predict how sick a sepsis patient will become. Researchers will enroll 70 adults arriving at the emergency department with sepsis to test t…

This study aims to understand how painful periods affect the academic performance and daily life of female medical students. Researchers will survey about 400 students at Sohag University to measure the severity of their pain and its impact on schoolwork, sleep, and mood. The goa…

This study aims to better understand a serious pregnancy condition called placenta accreta, where the placenta grows too deeply into the uterus. Researchers will use ultrasound to check if the placenta has invaded the cervix and measure cervical length in 200 pregnant women with …

This study aims to measure how common depression is among medical students at Sohag University. It will survey 300 students aged 18 to 25 to understand the scale of this mental health challenge. The goal is to gather information that could help improve support for students in the…

This study aims to measure how common latent tuberculosis infection is among patients receiving regular kidney dialysis at Sohag University Hospital. Researchers will test 200 adult dialysis patients using a standard skin test to detect hidden TB infection. The goal is to underst…

This study aims to understand why some people with bronchiectasis have worse outcomes during sudden symptom flare-ups. Researchers will observe 100 adult patients hospitalized for a flare-up to see if having other conditions like COPD, diabetes, or heart disease leads to longer h…

This study aims to understand how common heart thickening is in people with chronic kidney disease. Researchers will also observe whether a standard treatment for anemia (erythropoietin therapy) has any effect on reducing this heart thickening over six months. The study will invo…

This study aims to understand how doctors treat intermediate-stage liver cancer in real-world hospital settings and what survival outcomes patients experience. Researchers will observe and analyze the treatment choices and health records of about 200 adult patients at a single ca…

This study aims to understand if a protein in the blood (called FAP) can tell doctors about disease activity and lung scarring in rheumatoid arthritis and systemic sclerosis (scleroderma). Researchers will take a single blood sample from 111 people (patients and healthy volunteer…

This study aims to understand how common and how serious a specific type of heart problem is in people with end-stage kidney disease who receive regular dialysis. It will involve 100 adult patients and will use heart ultrasound scans to look for issues with how the heart relaxes …

Association between Benign Paroxysmal Positional Vertigo and Vitamin D deficiency