Can microneedling plus creams fade red stretch marks? new trial aims to find out

NCT ID NCT07154030

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-stage trial tests whether microneedling combined with either tretinoin 0.025% or timolol 0.5% can improve the appearance of red stretch marks (stria rubra). Researchers will enroll 300 adults and track changes through photos and skin checks. The goal is to see if these combinations work better than microneedling alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

microneedling with tretinoin 0.025% or timolol 0.5%

What this could lead to

If successful, this could offer a more effective way to reduce the appearance of red stretch marks.

What could go wrong

This is a very early Phase 1 trial, so results are uncertain. The treatments may not work better than existing options, and side effects like irritation or scarring are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Striae Distensae striae distensae, familial

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

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