New study tests two procedures to ease chronic migraine pain
NCT ID NCT07512219
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two procedures—a nerve block and a pulsed radiofrequency treatment—to see which works better for people with chronic migraine. About 70 adults who have not found relief from standard treatments will take part. The goal is to reduce headache pain and improve quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patient with Diagnosis of chronic migraine for \> 3 months. * migraine days ≥ 15 days/month. * Failure or inadequate response to standard medical treatment. Exclusion Criteria: * Secondary headache disorders. * Coagulopathy or anticoagulant therapy. * Infection at injection site. * History of cervical spine surgery. * Pregnancy or breastfeeding. * Previous PRF or occipital nerve surgery within last 3 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blocking a head artery to stop migraines: a new trial tests the idea
- Talking therapies take on migraine pain
- Exercise, diet, and sleep: a new attack plan against chronic migraine?
- Can a nerve procedure outlast botox for chronic migraine?
- Could blocking an extra nerve double migraine relief?
- Electric zaps to the brain may tame chronic migraine