Electric zaps to the brain may tame chronic migraine

NCT ID NCT07743814

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This trial tests whether a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can reduce the number of headache days in people with chronic migraine. Participants will receive either real or sham (inactive) stimulation over the motor cortex during three sessions, while continuing their usual preventive medications. The study tracks headache frequency over 12 weeks to see if the stimulation makes a meaningful difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Transcranial direct current stimulation (tDCS) — a non-invasive brain stimulation technique using a mild electrical current applied to the scalp over the primary motor cortex.
What this could lead to
If effective, tDCS could offer a drug-free option to reduce headache frequency in chronic migraine, potentially helping those who cannot tolerate preventive medications.
What could go wrong
This is a small early-stage trial with only 32 participants, and the effect may be modest or not lasting. As with any brain stimulation, there is a small risk of discomfort or side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital

    New Delhi, 110001, India

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Other studies related to the condition(s) this trial covers.