Double attack on migraine: botox plus nerve block shows promise
NCT ID NCT07535723
First seen Apr 23, 2026 · Last updated Jun 22, 2026 · Updated 13 times
Summary
This study tests whether combining Botox injections with a nerve block at the back of the head works better than either treatment alone for chronic migraine. About 90 adults with frequent migraines will receive one or both treatments. The goal is to see if the combo reduces headache days and improves quality of life more effectively.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beni-Suef University Hospital
Al Fayyum, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
OnabotulinumtoxinA (Botox) and local anesthetic (lidocaine)
What this could lead to
If it works, this combination could offer faster and more lasting relief for people with chronic migraine, reducing headache days and improving daily life.
What could go wrong
This is a small, early-stage trial with only 90 participants. The combination may not be more effective than either treatment alone, and there are risks like injection site pain or allergic reaction.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.