Double attack on migraine: botox plus nerve block shows promise
NCT ID NCT07535723
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether combining Botox injections with a nerve block at the back of the head works better than either treatment alone for chronic migraine. About 90 adults with frequent migraines will receive one of the treatments or both. The goal is to see if the combination reduces headache days and improves daily life more effectively.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- OnabotulinumtoxinA (Botox) and local anesthetic (lidocaine) nerve block
- What this could lead to
- If it works, this could offer a more effective way to reduce migraine days and improve quality of life for people with chronic migraine.
- What could go wrong
- This is a small, early-stage trial with only 90 participants. The combination may not work better than either treatment alone, and results may not apply to everyone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Beni-Suef University Hospital
Al Fayyum, Egypt
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