Sohag University

This trial tests whether microscopic surgery to repair varicoceles (enlarged veins in the scrotum) works better than antioxidant medication for men with cryptozoospermia—a condition where very few sperm are present in semen. About 69 men with clinical varicoceles will be randomly…

This study tested whether adding letrozole to misoprostol helps end a nonviable pregnancy in the first trimester more effectively than misoprostol alone. 400 women with missed miscarriage took part. Researchers measured bleeding, time to complete abortion, and side effects.

This study looked at whether adding a drug called epirubicin to the standard two-drug chemotherapy (paclitaxel and carboplatin) helps people with advanced endometrial cancer. Sixty patients were enrolled to see if the three-drug combo is better at controlling the disease before s…

This study looked at whether a class of diabetes drugs called SGLT2 inhibitors can improve fatty liver disease in people with type 2 diabetes. 150 adults took the drugs for 6 months, and researchers measured changes in liver stiffness, fat levels, and blood sugar control. The goa…

This study looked at how to treat a pregnancy that grows in the scar from a previous C-section, a rare but dangerous condition. Researchers followed 37 women in their first trimester to see how well surgical removal worked. The main focus was on preventing heavy bleeding and flui…

This study tested a new surgical technique called lateral rectus muscle strangulation to treat exotropia, a condition where one or both eyes turn outward. Twelve people aged 4 and older with intermittent exotropia or exophoria underwent the procedure. The goal was to weaken the e…

This study looked at whether a low-carbohydrate diet could help children and teens (ages 10-18) with type 1 diabetes manage their blood sugar better. Twenty-five participants followed the diet for a short time, and researchers measured their blood glucose levels. The goal was to …

This study looked at how aerobic and resistance exercise impact blood sugar levels after eating in children and teens (ages 10-18) with type 1 diabetes. Forty-nine participants did different types of exercise, and their blood sugar was tracked for six hours after meals. The goal …

This study tested whether a special ultrasound technique called strain elastography can help tell the difference between harmless and cancerous breast lumps. Researchers measured how stiff each lump was, since cancer tends to be stiffer. The goal was to improve diagnosis and redu…

This completed study looked at whether a special PET scan using 18F-FDG can help doctors more accurately diagnose, stage, and track stomach cancer. Researchers studied 50 patients with confirmed gastric cancer, comparing scan results to other tests. The goal was to see if this im…

This study tests a specially designed set of infection-prevention steps (a 'bundle') for people undergoing coronary artery bypass graft (CABG) surgery. The goal is to see if this bundle reduces surgical wound infections, both superficial and deep. The trial includes 200 participa…

This trial tests whether a nerve block called the erector spinae plane block can better control pain during extracorporeal shock wave lithotripsy (ESWL), a common procedure to break up kidney stones. Sixty adults with 2-3 cm kidney stones will receive either the nerve block or a …

This trial compares two common pain medicines—gabapentin and diclofenac sodium—given before laparoscopic gallbladder removal. The goal is to see which one provides better pain relief after surgery. Sixty adults aged 20 to 60 with chronic gallbladder inflammation are taking part. …

This study compared evening primrose oil (a natural oil) with misoprostol (a standard drug) for softening the cervix before operative hysteroscopy. 230 women participated. Researchers measured how easily the cervix could be dilated and noted any complications like bleeding or tea…

This study looked at 100 adults getting a gastrointestinal endoscopy to compare two drug combos for sedation: dexmedetomidine-propofol versus ketamine-propofol. The goal was to see which combo provides better stability during the procedure and fewer side effects like nausea, vomi…

This study looked at whether a nose spray medicine called midazolam can help calm preschool children (ages 2-6) before they have surgery to remove their tonsils and adenoids. The goal was to make the children less anxious and more comfortable before anesthesia. The study included…

This study tested whether adding the oral drug midodrine to standard IV norepinephrine helps critically ill patients with shock stop IV blood pressure support sooner. 112 stable ICU patients on low-dose norepinephrine were included. The goal was to see if midodrine shortens weani…

This study compared two spinal anesthetics—prilocaine and bupivacaine—in 142 women having planned C-sections. Researchers measured how quickly each drug caused numbness and muscle relaxation, and how long those effects lasted. The goal was to see if prilocaine could be a good alt…

This study tested whether giving the sedative dexmedetomidine during open heart surgery can help protect patients' thinking and memory afterward. Researchers measured brain function with a simple test and checked a blood marker of brain injury. The trial included 32 adults having…

This study tested a special type of prostate surgery (TURP) designed to preserve the ability to ejaculate. 90 men with an enlarged prostate who had not responded to medication took part. The goal was to see if the surgery could improve urination while maintaining sexual function.

This study investigates whether zinc oxide nanoparticles can inhibit the growth and biofilm formation of Acinetobacter baumannii, a bacterium that causes severe hospital-acquired infections like pneumonia and bloodstream infections. Researchers will collect samples from 150 patie…

This study compares how often bowel obstruction occurs after two types of appendix removal surgery: open appendectomy and laparoscopic appendectomy. Fifty people with acute appendicitis will be randomly assigned to one of the two procedures. The goal is to see whether the minimal…

This study looks back at medical records of women with triple-negative breast cancer who had chemotherapy and radiation before surgery. It focuses on those who still had cancer cells left after treatment (residual disease) and tracks how long they lived without the cancer coming …

This study looks at two ways to examine the uterine cavity after women have had hysteroscopic surgery for conditions like polyps, fibroids, or a uterine septum. One method is a non-invasive 3D ultrasound; the other is an office hysteroscopy, which involves inserting a small camer…

This study looks at how the womb lining heals after different types of womb-sparing surgery for placenta accreta, a serious pregnancy condition where the placenta grows too deeply into the womb wall. Researchers will use a small camera (hysteroscopy) three months after surgery to…

This study looked at how often acute kidney injury happens in people with liver cirrhosis, and what factors might increase the risk. Researchers at Sohag University Hospital followed 180 adult patients with cirrhosis, excluding those with pre-existing kidney disease or other majo…

This study looked at 80 people who had a heart attack but no major blockages in their heart arteries (called MINOCA). Researchers checked if the ratio of white blood cells to a platelet marker in their blood could predict short-term health outcomes. The goal was to see if this si…

This study looked at 50 adults on maintenance hemodialysis to find the link between how fast fluid is removed (ultrafiltration rate) and sudden drops in blood pressure during treatment. The goal was to identify a safer threshold to prevent intradialytic hypotension. Researchers a…

This study looked at which birth control methods married women of childbearing age (15–49) use at a medical center in El_Balyana, Egypt. Researchers collected information from 385 women to understand family planning trends. The goal was to gather data that could help improve acce…

This study looked at a protein called MMP-9, which is involved in breaking down joint tissue in rheumatoid arthritis. Researchers measured genetic variations of MMP-9 in 60 people with active rheumatoid arthritis and compared them to healthy volunteers. The goal was to better und…

This study compared two types of laparoscopic surgery for early-stage colon cancer: conventional colectomy and complete mesocolic excision (CME). Researchers looked at 150 patients in Upper Egypt to see which surgery removed more lymph nodes and caused fewer complications. The go…

This completed study looked at skin samples from 40 people with psoriasis to understand how certain immune cells (CD4+ T cells) and a protein called S100A7 behave in psoriatic skin. Researchers used special staining techniques to measure these components. The goal was to learn mo…

This study looked at how common prediabetes is in people with end-stage kidney disease who are on dialysis. Researchers screened 262 adult dialysis patients who had never been diagnosed with diabetes or prediabetes. The goal was to find out how many had prediabetes, which can inc…

This completed study used a special eye scan called OCTA to look at tiny blood vessels in the retina of 200 people with type 2 diabetes who had no signs of eye disease on a standard exam. The goal was to see if the duration of diabetes affects these vessels. The findings could he…

This study looked at 100 patients with aortic valve sclerosis (a stiffening of the heart valve) and chest pain to see if a blood fat called lipoprotein(a) is linked to the severity of blocked heart arteries. Researchers measured Lp(a) levels from blood samples and compared them t…

This study looked at 20 people with knee arthritis who had a surgery called high tibial osteotomy (HTO) to realign their knee. The goal was to see how the surgery changed ankle pain and ankle joint alignment. Researchers measured pain and bone angles before and after surgery. The…