New drug combo may speed up miscarriage management
NCT ID NCT07636317
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether adding letrozole to misoprostol helps end a nonviable pregnancy in the first trimester more effectively than misoprostol alone. 400 women with missed miscarriage took part. Researchers measured bleeding, time to complete abortion, and side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Letrozole and Misoprostol
What this could lead to
If adding letrozole works better, it could offer a more effective and faster medication option for managing missed miscarriage.
What could go wrong
This is a completed trial, but results may not apply to all women. Side effects like nausea, fever, and shivers are possible with misoprostol.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sohag University
Sohag, 82511, Egypt