Sohag University

This trial tests two medications, norepinephrine and phenylephrine, to see which one better prevents low blood pressure caused by spinal anesthesia in patients aged 60 and older undergoing hip surgery. Participants receive one of the two drugs right after the spinal block, and th…

This trial is testing whether a keyhole surgery called TAPP can safely and effectively fix inguinal hernias that have come back after a previous operation. Ten adults will undergo the procedure and be monitored for pain, complications, and whether the hernia returns. Because scar…

This study tests whether giving a lower dose of protamine (a drug that reverses the blood thinner heparin) after heart-lung bypass is safe and effective. About 195 adults having elective heart surgery will be randomly assigned to one of three protamine doses. The goal is to see i…

This study tests a new surgical approach for complex fractures of the distal ulna (the forearm bone on the pinky side). The method uses both a flexible nail inside the bone and a small metal plate on the outside to hold the break together. Researchers will check how well the bone…

This study compares two common surgical methods—cannulated screws and K-wires—for fixing broken wrists in adults aged 18-60. The goal is to see which approach leads to better bone healing and hand strength. About 34 participants will be assigned to one of the two treatments and f…

This study tests a surgical procedure using two compression screws to fix ankle fractures that have not healed after at least 6 months. Ten adults aged 18 to 65 with a specific type of non-union will be treated and followed for 12 weeks to see if the bone heals and pain improves.…

This study compares two surgical techniques for fixing broken metatarsal bones in the foot: transverse pinning and antegrade intramedullary pinning. About 40 adults with displaced fractures will be randomly assigned to one method. Researchers will measure bone healing time, foot …

This study compares two techniques for removing silicone oil from the eye after retinal detachment repair. About 200 people who previously had silicone oil placed in their eye will be randomly assigned to one of two removal methods: a special vitrectomy machine or a spring-loaded…

This study is testing whether combining fat grafting with a muscle flap from the back can improve delayed breast reconstruction after mastectomy. Twenty women who had a nipple-sparing mastectomy will receive the procedure. The main goal is to see if it reduces wound infections or…

This study tests whether a combination of two drugs (venetoclax and low-dose cytarabine) can help adults with acute myeloid leukemia (AML) stay in remission longer. Participants are 18–60 years old, have achieved complete remission after initial chemotherapy, and are not able to …

This study compares two procedures for treating type II cesarean scar pregnancy, a rare condition where a pregnancy implants in a previous C-section scar. 68 women in their first trimester will be randomly assigned to either surgical removal or ultrasound-guided evacuation. The g…

This study tests how well a belly ultrasound can find internal scar tissue (adhesions) before keyhole surgery. Scar tissue can make it risky to insert the first surgical tool, so knowing where it is could help avoid injury. The study will include 74 women who have had past abdomi…

This study looks at whether two simple blood markers—albumin-to-globulin ratio and prognostic nutritional index—can help predict disease activity in people with lupus. Researchers will measure these markers in 200 participants and compare them with standard disease activity score…

This study is testing whether a simple ultrasound procedure, called saline infusion sonohysterography (SIS), can accurately detect pelvic adhesions (scar tissue) in infertile women. Researchers will compare SIS results to those from laparoscopy, the current standard. If SIS prove…

This study compares two methods for finding the cause of abnormal bleeding in women aged 40-55: a non-invasive 3D ultrasound and a more invasive hysteroscopy (a camera inserted into the uterus). Researchers will check how accurate the 3D ultrasound is compared to hysteroscopy. Th…

This study aims to find out which nerve block injection works better for people with frozen shoulder: a shoulder anterior capsular block (SHAC) or a suprascapular nerve block. Fifty adults with frozen shoulder will be randomly assigned to receive one of the two injections. Resear…

This study tests a surgery called Zadek osteotomy for people with Haglund's syndrome, a condition causing painful heel bumps. Researchers will enroll 30 adults who haven't improved after six months of other treatments. The goal is to see if the surgery reduces pain, improves foot…

This observational study will compare blood fat (lipid) levels in 200 adults with chronic kidney disease—half with diabetes and half without. Researchers want to find out if having diabetes leads to worse fat problems in these patients. Participants will fast for 10 hours before …

This study is looking at whether people with a common inner-ear condition called benign paroxysmal positional vertigo (BPPV) have lower vitamin D levels than those without it. Researchers will compare vitamin D in 160 adults — half with BPPV and half without. The goal is to see i…

This study looks at whether a simple heart ultrasound can help predict which patients with a blood clot in the lungs (pulmonary embolism) are at higher risk for serious problems. Researchers will check right heart function in 112 adults and track outcomes like breathing failure, …

This study aims to see how common fatty liver disease (MASLD) is in people with underactive thyroid (hypothyroidism) who do not have diabetes. Researchers will use blood tests, ultrasound, and a special liver scan (FibroScan) to check 200 adults. The goal is to understand if thyr…

This study looks at 200 adults with well-controlled rheumatoid arthritis to find ways to predict when a disease flare might occur. Researchers will track symptoms and check blood markers every 3 months. The goal is to help doctors adjust treatment early and prevent flares.

This study looks at 100 COPD patients on breathing machines to see if a new ultrasound-based method (D-RSBI) is better than the standard method (RSBI) at predicting when they can safely breathe on their own. Researchers will measure both methods during a breathing trial and check…

This study will use nerve conduction tests to check for nerve damage in 60 adults with rheumatoid arthritis. Half are taking baricitinib (Olumiant), a JAK inhibitor, and the other half are on standard disease-modifying drugs. The goal is to see if baricitinib is linked to a highe…

This study is enrolling 100 adults with stable bronchiectasis (a chronic lung condition) to see if certain blood markers and CT scan findings can predict who will have frequent flare-ups. Researchers will measure inflammation markers like CRP and cell ratios, along with detailed …

This study compares two techniques for guiding a needle into a blocked leg artery from the opposite direction (retrograde). One uses a live X-ray map, the other uses ultrasound. Researchers want to see which is safer and more successful in 32 people with severe leg artery disease…

This study looks at whether a tool called the Modified SOAR score can help doctors predict which stroke patients are at higher risk of dying soon after they are admitted to the hospital. Researchers will follow 60 adults with acute stroke at Sohag University Hospitals, collecting…

This study is checking if thyroid problems (too much or too little thyroid hormone) change results of liver function tests. Researchers will measure bilirubin levels in 100 adults aged 20-60, comparing those with thyroid disease to healthy volunteers. The goal is to better unders…

This study looks at 100 people with uncomplicated retinal detachment who need surgery. Doctors will peel a thin membrane from the back of the eye either during the first surgery or later when silicone oil is removed. The goal is to see which timing leads to fewer complications.

This study looks at kidney function in 100 children with epilepsy, aged 1 month to 15 years, at Sohag University Hospital. Researchers will measure blood and urine markers and use ultrasound to check for kidney stones or damage linked to long-term anti-seizure medication. No new …

This study looks back at how well a blood-filtering procedure called plasma exchange works in children with kidney issues at Sohag University Hospital. Researchers will review the medical records of 25 children to see why the procedure was used, how it went, and any problems that…

This study looks at 180 non-diabetic adults with early coronary artery disease to see if a measure called the triglyceride-glucose index is linked to how many arteries are blocked. Participants will have a standard heart imaging test (angiogram) to map their artery disease. The g…