Blood sugar marker could reveal hidden heart risks in Non-Diabetics
NCT ID NCT07154186
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at 180 non-diabetic adults with early coronary artery disease to see if a measure called the triglyceride-glucose index is linked to how many arteries are blocked. Participants will have a standard heart imaging test (angiogram) to map their artery disease. The goal is to find a simple way to identify higher-risk patients who might need closer monitoring.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better predict heart disease severity in non-diabetic patients using a simple blood test.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to direct changes in patient care, and results might not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This cross-sectional study will be conducted at Sohag University Hospitals, following approval from the institutional ethics committee.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years old. * Both sexes. * Non-diabetic patients \[no history of diabetes, hemoglobin A1C (HbA1C) \< 6.5%, fasting glucose \< 126 mg/dL\]. * Confirmed diagnosis of coronary artery disease (CAD) by coronary angiography. Exclusion Criteria: * Known diabetes mellitus (type 1 or type 2). * Previous history of coronary revascularization. * Severe hepatic or renal dysfunction \[alanine transaminase (ALT)/aspartate aminotransferase (AST) ≥ 5× upper limit of normal (ULN), estimated glomerular filtration rate (eGFR)\< 30 mL/min/1.73 m²\]. * Malignant disease, autoimmune disease, or systemic inflammatory disorders. * Current use of triglyceride-lowering medications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sohag University
RECRUITINGSohag, 82511, Egypt
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