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New CT scanner aims to cut unnecessary heart procedures

NCT ID NCT07831304

NEW Diagnosis Sponsor: IRCCS San Raffaele Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers compare two types of CT scanners for imaging heart arteries in people with suspected chronic coronary syndrome. One scanner uses standard energy-integrating detectors, while the other uses newer photon-counting detectors that may produce clearer pictures with fewer false alarms. The trial tracks how often each scan correctly identifies narrowed arteries, along with costs and follow-up care over two years. About 630 adults who need a coronary CT angiogram take part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
photon-counting detector CT (PCD-CT) versus energy-integrating detector CT (EID-CT) for coronary CT angiography
What this could lead to
If photon-counting CT proves more accurate, it could reduce unnecessary invasive heart procedures and lower healthcare costs for people with suspected coronary artery disease.
What could go wrong
The trial may show no meaningful difference between the two scanners, or the newer technology may not be widely available or affordable. Results from this single healthcare system may not apply elsewhere.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 630 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2026

Expected to finish

Sep 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * clinical indication to perform CCTA for CAD assessment according to 2024 ESC Guidelines Exclusion Criteria: * Refusal to participate in the study * Age \<18 years old * Severe reduction in eGFR (\<30 mL/min)

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Conditions

The condition(s) this trial relates to.

coronary artery disorder disease myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Computed tomography angiography Coronary artery disease

Contacts and locations

Locations

  • Advanced Imaging for Personalized Medicine/Radiologia DiMer

    Milan, Milano, 20132, Italy

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