Could a diabetes and cholesterol drug combo regrow hair?
NCT ID NCT07696585
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This trial tests whether a custom cream containing metformin (a diabetes drug), simvastatin (a cholesterol drug), and betamethasone (a steroid) can regrow hair in people with patchy alopecia areata, an autoimmune condition causing hair loss. Participants apply the cream twice daily for 12 weeks. The study measures hair regrowth using a standard scalp scoring system. It aims to find a safer, more effective topical option for those who haven't responded to or are dissatisfied with current treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- topical cream containing metformin 30%, simvastatin 2%, and betamethasone valerate 0.1%
- What this could lead to
- If successful, this could offer a new, safe, and effective topical treatment option for people with patchy alopecia areata, potentially reducing the need for systemic therapies.
- What could go wrong
- This is an early-stage trial with a small number of participants (60). The combination cream may cause skin irritation or allergic reactions, and its effectiveness compared to existing treatments is not yet proven.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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