Can a simple MRI spot uterine cancer without a biopsy?
NCT ID NCT07402421
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test whether a special type of MRI called diffusion-weighted imaging can accurately tell the difference between benign (non-cancerous) and malignant (cancerous) growths in the lining of the uterus. Researchers will compare the MRI results with the standard method—examining tissue under a microscope after a biopsy. The goal is to see if the MRI can be a reliable, non-invasive alternative for diagnosis. The study plans to enroll 30 women with abnormal uterine bleeding or suspicious findings on ultrasound.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Diffusion-weighted magnetic resonance imaging (DWI MRI)
- What this could lead to
- If successful, DWI MRI could become a reliable non-invasive way to diagnose endometrial lesions, potentially reducing the need for invasive biopsies.
- What could go wrong
- This is a small, early-stage diagnostic study with only 30 participants. The accuracy may not be high enough to replace biopsy, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sohag University Hospital
Sohag, Sohag Governorate, Egypt