New weapon against superbug: can Ceftazidime-Avibactam beat Drug-Resistant klebsiella?

This study looks at how well the antibiotic combination ceftazidime-avibactam works against a hard-to-treat bacteria called Klebsiella pneumoniae that produces carbapenemases (enzymes that break down many antibiotics). Researchers will collect samples from 100 hospitalized patients with infections like pneumonia, urinary tract infections, or wound infections. They will test the bacteria's resistance patterns and look for specific resistance genes using PCR. The goal is to understand which infections this drug can treat effectively.