Breath of relief: ketamine or magnesium mist may stop Post-Surgery sore throat

NCT ID NCT07381036

First seen Feb 02, 2026

Summary

This study tests whether inhaling ketamine or magnesium sulfate before surgery can prevent the sore throat that often follows general anesthesia with a breathing tube. 150 adults having elective surgery will be randomly assigned to receive one of these treatments or a placebo. The goal is to see which works better at reducing pain and discomfort in the throat after the operation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketamine and magnesium sulfate (nebulized)

What this could lead to

If successful, this could provide a simple, low-cost way to prevent sore throat after surgery with general anesthesia.

What could go wrong

This is a small, early-stage trial with no phase designation. The results may not apply to all surgeries or patients, and side effects like sedation or nausea are possible.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.