Breath of relief: ketamine or magnesium mist may stop Post-Surgery sore throat

NCT ID NCT07381036

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether inhaling ketamine or magnesium sulfate before surgery can prevent the sore throat that often follows general anesthesia with a breathing tube. 150 adults having elective surgery will be randomly assigned to receive one of these treatments or a placebo. The goal is to see which works better at reducing pain and discomfort in the throat after the operation.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
ketamine and magnesium sulfate (nebulized)
What this could lead to
If successful, this could provide a simple, low-cost way to prevent sore throat after surgery with general anesthesia.
What could go wrong
This is a small, early-stage trial with no phase designation. The results may not apply to all surgeries or patients, and side effects like sedation or nausea are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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The condition terms exactly as the trial's registrant entered them.

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