Anemia
MONDO:0002280A reduction in the number of red blood cells, the amount of hemoglobin, and/or the volume of packed red blood cells. Clinically, anemia represents a reduction in the oxygen-transporting capacity of a designated volume of blood, resulting from an imbalance between blood loss (through hemorrhage or hemolysis) and blood production. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability.
Also known as: anaemia (disease), anemia, anemia (disease)
975 clinical trials for this condition and its sub-types, 258 tagged with Anemia itself.
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Sub-types of Anemia
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Aplastic anemia 110 trials · 411 incl. sub-types
4 sub-types
- Acquired aplastic anemia 38 trials · 303 incl. sub-types Sub-types →
- Inherited aplastic anemia 2 trials · 53 incl. sub-types Sub-types →
- Idiopathic aplastic anemia 9 trials
- Myelophthisic anemia 0 trials
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Normocytic anemia 0 trials · 180 incl. sub-types
1 sub-type
- Hemolytic anemia 19 trials · 180 incl. sub-types Sub-types →
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Microcytic anemia 0 trials · 130 incl. sub-types
3 sub-types
- Hypochromic microcytic anemia 0 trials · 123 incl. sub-types Sub-types →
- Fetal erythroblastosis 7 trials
- IRIDA syndrome 0 trials
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Hypochromic anemia 0 trials · 123 incl. sub-types
1 sub-type
- Hypochromic microcytic anemia 0 trials · 123 incl. sub-types Sub-types →
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Beta-thalassemia and related diseases 0 trials · 99 incl. sub-types
7 sub-types
- Beta thalassemia 73 trials · 99 incl. sub-types Sub-types →
- Hemoglobin E-beta-thalassemia syndrome 5 trials
- Beta-thalassemia-X-linked thrombocytopenia syndrome 0 trials
- Delta-beta-thalassemia 0 trials
- Hemoglobin C-beta-thalassemia syndrome 0 trials
- Hemoglobin Lepore-beta-thalassemia syndrome 0 trials
- Hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome 0 trials
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Congenital anemia 0 trials · 58 incl. sub-types
8 sub-types
- Fanconi anemia 29 trials · 42 incl. sub-types Sub-types →
- Congenital nonspherocytic hemolytic anemia 1 trial · 12 incl. sub-types Sub-types →
- Myopathy, lactic acidosis, and sideroblastic anemia 3 trials Sub-types →
- Congenital dyserythropoietic anemia type 1 1 trial Sub-types →
- Congenital dyserythropoietic anemia type 2 1 trial
- Congenital dyserythropoietic anemia type 3 0 trials
- Congenital dyserythropoietic anemia type 4 0 trials
- Severe congenital hypochromic anemia with ringed sideroblasts 0 trials
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Anemia due to chronic disorder 34 trials
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Pure red-cell aplasia 5 trials · 24 incl. sub-types
2 sub-types
- Diamond-Blackfan anemia 17 trials Sub-types →
- Adult pure red cell aplasia 2 trials
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Neonatal anemia 7 trials · 23 incl. sub-types
3 sub-types
- Twin to twin transfusion syndrome 14 trials Sub-types →
- Anemia of prematurity 4 trials
- Kernicterus due to isoimmunization 0 trials
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Deficiency anemia 3 trials · 16 incl. sub-types
3 sub-types
- Hereditary anemia 2 trials · 13 incl. sub-types Sub-types →
- Acquired deficiency anemia 0 trials Sub-types →
- Protein-deficiency anemia 0 trials
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Pancytopenia 15 trials
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Anemia due to enzyme disorder 1 trial · 14 incl. sub-types
4 sub-types
- Anemia due to erythrocyte enzyme disorder 0 trials · 13 incl. sub-types Sub-types →
- Gamma-glutamylcysteine synthetase deficiency 0 trials
- Glutathione synthetase deficiency without 5-oxoprolinuria 0 trials
- Hemolytic anemia due to erythrocyte adenosine deaminase overproduction 0 trials
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Sideroblastic anemia 0 trials · 14 incl. sub-types
3 sub-types
- Inherited sideroblastic anemia 2 trials · 7 incl. sub-types Sub-types →
- Myelodysplastic syndrome with ring sideroblasts 7 trials
- Pyridoxine-responsive sideroblastic anemia 0 trials
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Macrocytic anemia 0 trials · 11 incl. sub-types
2 sub-types
- Megaloblastic anemia 1 trial · 9 incl. sub-types Sub-types →
- Myelodysplastic syndrome associated with isolated del(5q) 2 trials
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Hemoglobin C disease 2 trials
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Hereditary methemoglobinemia 0 trials · 1 incl. sub-types
5 sub-types
- Methemoglobinemia type 4 1 trial
- Hemoglobin M disease 0 trials
- Methemoglobin reductase deficiency 0 trials
- Methemoglobinemia due to deficiency of methemoglobin reductase 0 trials
- Methemoglobinemia, alpha type 0 trials
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Hemoglobin D disease 0 trials
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Hemoglobin E disease 0 trials
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Hemoglobinopathy Toms River 0 trials
Most studied deeper sub-types
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Can a new drug calm the immune System's attack on blood cells?
Disease control CompletedThis study is testing an experimental drug called povetacicept in adults with autoimmune cytopenias — conditions where the immune system mistakenly destroys blood cells, leading to low platelet counts (immune thrombocytopenia) or anemia (autoimmune hemolytic anemia and cold agglu…
Phase 1/2 • Sponsor: Alpine Immune Sciences Inc, A Subsidiary of Vertex • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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New anemia pill for dialysis patients tested against standard shots
Disease control CompletedThis study tests a new pill, vadadustat, taken three times a week, against the usual injected medicine for anemia in people with kidney failure who are on dialysis. About 350 adults will take part to see if the pill can safely keep their red blood cell levels in a healthy range. …
Phase 3 • Sponsor: Akebia Therapeutics • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Can catching anemia months before joint surgery speed recovery?
Disease control CompletedThis trial tests whether screening for anemia at the time a patient consents to hip or knee replacement surgery, which is usually 4 to 6 months before the operation, leads to better outcomes than the standard approach of testing only 2 to 4 weeks before surgery. About 800 adults …
Sponsor: Ottawa Hospital Research Institute • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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New hope for rare blood disorder: crovalimab trial underway
Disease control CompletedThis study tests a new medicine, crovalimab, for paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disease that destroys red blood cells. It involves healthy volunteers and people with PNH to check safety and how well the drug works. The goal is to control the disease, not …
Phase 1/2 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Can a pill replace the needle for anemia in diabetic kidney disease?
Disease control CompletedThis trial tests whether an oral drug called roxadustat can treat anemia in people with diabetic nephropathy and chronic kidney disease as effectively as the standard erythropoietin injections. About 64 adults aged 18 to 75 will receive either roxadustat pills three times a week …
Sponsor: Hanzla Arshad • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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One infusion before surgery: could it cut transfusions?
Disease control CompletedThis trial tests whether a single intravenous dose of iron, given 3-4 weeks before elective abdominal or pelvic surgery, can raise hemoglobin levels in patients with iron-deficiency anemia. The goal is to see if this simple pre-op step reduces the need for blood transfusions, low…
Phase 4 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Herbal remedy vs. standard drug: a new hope for thalassemia iron overload?
Disease control CompletedThis trial compares an experimental herbal formulation called Irochel against the standard medication deferoxamine in managing iron overload caused by repeated blood transfusions in thalassemia patients. The study involves 132 children and adolescents aged 10 to 16 with transfusi…
Phase 3 • Sponsor: Hamdard University • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Can a new drug match a standard anemia treatment for dialysis patients?
Disease control CompletedThis trial is testing whether a new version of darbepoetin alfa works as well as the standard treatment (Aranesp) for anemia in people with chronic kidney disease who are on dialysis. Participants will receive either the new drug or Aranesp by injection every other week for 24 we…
Phase 3 • Sponsor: Nanogen Pharmaceutical Biotechnology Joint Stock Company • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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New cord blood matching method could expand transplant access for blood cancer patients
Disease control CompletedThis study tests a new approach to stem cell transplants for people with blood cancers like leukemia and lymphoma. Patients receive a combination of umbilical cord blood and stem cells from a family member, with the cord blood chosen based on specific genetic markers rather than …
Phase 2 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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Can a drug revive blood cell production in children with aplastic anemia?
Disease control CompletedThis phase II trial is investigating whether eltrombopag, a drug that stimulates platelet production, can help children with severe aplastic anemia when combined with standard immunosuppressive therapy. The study will enroll children with newly diagnosed, relapsed, or refractory …
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Can a new pill tame myelofibrosis?
Disease control CompletedThis trial is testing an experimental oral drug called PXS-5505 (amsulostat) in people with myelofibrosis, a type of bone marrow cancer. The study focuses on patients who are not eligible for a stem cell transplant. The main goal is to see if the drug is safe and tolerable, and t…
Phase 1/2 • Sponsor: Syntara • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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Can a gentler iron pill break the anemia cycle in IBD?
Disease control CompletedThis trial tests whether ferric maltol, an oral iron supplement, can safely raise hemoglobin levels in adults with inflammatory bowel disease (IBD) who have iron deficiency anemia and have not responded to or cannot tolerate standard ferrous iron pills. Participants take either f…
Phase 3 • Sponsor: Jiangsu Aosaikang Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Tailored hormone dosing may spare preemies from blood transfusions
Disease control CompletedThis phase 2 trial tests whether personalized dosing of epoetin alfa—a lab-made hormone that boosts red blood cell production—can reduce or eliminate the need for blood transfusions in very low birth weight premature infants with neonatal anemia. Researchers will study how the dr…
Phase 2 • Sponsor: University of Iowa • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Could smaller blood tubes save patients from unnecessary transfusions?
Disease control CompletedThis study tests whether using smaller tubes for routine blood draws can reduce the number of red blood cell transfusions needed by anemic patients in intensive care. About 688 adults with low hemoglobin will be randomly assigned to have blood drawn with either small or standard-…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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Gentler transplant shows promise for kids with blood diseases
Disease control CompletedThis study tests a milder chemotherapy and immune-suppressing regimen before a stem cell transplant for children and young adults with non-malignant blood disorders like sickle cell disease or immune deficiencies. The goal is to safely achieve donor cell engraftment with fewer si…
Phase 2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Blood transfusion thresholds tested to save elderly surgical patients
Disease control CompletedThis study tests whether giving blood transfusions more liberally (when hemoglobin drops to 9 g/dL) versus more restrictively (when it drops to 7.5 g/dL) reduces death and serious complications like heart attack, stroke, or kidney injury in patients aged 70 and older undergoing n…
Phase 3 • Sponsor: Johann Wolfgang Goethe University Hospital • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Iron fix: new study tests best way to boost energy in women with hidden deficiency
Disease control CompletedThis study looked at 1331 women aged 18-45 who had low iron stores but normal hemoglobin (no anemia). They were split into three groups: one got daily oral iron pills for 3 months, another got three IV iron infusions over 3 months, and a third got no treatment. The goal was to se…
Sponsor: Akram Medical Complex • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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New stem cell transplant approach shows promise for blood cancer patients without full matches
Disease control CompletedThis Phase 3 trial tested a stem cell transplant using blood stem cells from a half-matched (haploidentical) donor in 21 people with various blood cancers. The goal was to see if this approach could help patients who don't have a fully matched donor. Participants received chemoth…
Phase 3 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Could heart failure drugs boost oral Iron's power against anemia?
Disease control CompletedThis study looks at whether heart failure patients with iron deficiency anemia respond better to oral iron supplements when they are also taking a type of heart medication called SGLT2 inhibitors. Participants take oral iron for three to four months, then pause treatment while do…
Phase 3 • Sponsor: Universidade do Porto • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Could a JAK inhibitor improve stem cell transplant success in myelofibrosis?
Disease control CompletedThis phase 2 trial tests whether giving ruxolitinib (Jakafi) before, during, and after a stem cell transplant can improve outcomes for people with myelofibrosis. The study includes patients with intermediate-2 or high-risk disease, or intermediate-1 with additional risk factors. …
Phase 2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Could a lower dose of an old antibiotic tame Drug-Resistant TB?
Disease control CompletedThis study tests whether a low daily dose of the antibiotic linezolid, added to a personalized combination of other drugs, is safe and tolerable for people with multidrug-resistant tuberculosis (MDR-TB). Participants take either linezolid or a placebo for 16 weeks, alongside thei…
Phase 1/2 • Sponsor: Centers for Disease Control and Prevention • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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One infusion could beat daily pills for Post-Birth anemia
Disease control CompletedThis study tests whether a single intravenous (IV) dose of iron works better than daily oral iron pills to treat moderate anemia in new mothers. About 4,800 women who have moderate anemia 6 to 48 hours after delivery will receive either a one-time IV iron infusion plus folic acid…
Phase 3 • Sponsor: NICHD Global Network for Women's and Children's Health • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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New hope for rare blood disorder: experimental pill reduces need for transfusions
Disease control CompletedThis study tested a drug called bitopertin in 15 adults with Diamond-Blackfan anemia (DBA), a rare inherited condition that causes severe anemia. Participants took the pill daily for 8 months, with doses possibly increasing over time. The goal was to see if the drug could raise h…
Phase 1/2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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IV iron may beat pills for anemia in late pregnancy
Disease control CompletedThis study tests whether a single intravenous dose of ferumoxytol raises hemoglobin more effectively than daily oral ferrous sulfate in pregnant women with iron deficiency anemia. Participants are between 24 and 34 weeks pregnant with a single baby. The trial measures hemoglobin …
Phase 3 • Sponsor: Stanford University • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Experimental drug ANX005 targets blood cell destruction in autoimmune anemia
Disease control CompletedThis phase 2 trial investigates ANX005, an investigational drug given intravenously, for people with warm autoimmune hemolytic anemia (wAIHA). The study aims to assess the safety and tolerability of repeated doses, and to measure changes in blood markers like hemoglobin and bilir…
Phase 2 • Sponsor: Annexon, Inc. • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Could a month of iron before knee or hip surgery cut transfusion risk?
Disease control CompletedThis trial investigates whether anemic patients scheduled for hip or knee replacement surgery benefit from taking an iron supplement (Sideremil Vita) for 30 days before the operation, compared to taking it for only 15 days. The goal is to see if the longer treatment reduces the n…
Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Hormone drug may slow Aging-Related diseases in rare condition
Disease control CompletedThis study tested whether low doses of the hormone drug danazol can slow the shortening of telomeres—the protective caps on DNA—in people with telomere diseases. These conditions can cause bone marrow failure, lung scarring, and liver damage. Eighteen participants took danazol fo…
Phase 2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Drug cocktail may cut transfusions for kids with thalassemia
Disease control CompletedThis study tested whether giving children with transfusion-dependent thalassemia a combination of hydroxyurea and thalidomide works better than either drug alone. Ninety children aged 3-18 were split into three groups: one getting both drugs, one getting only hydroxyurea, and one…
Phase 4 • Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Experimental drug RAD001 tested for tough leukemias and lymphomas
Disease control CompletedThis study tested the drug RAD001 (everolimus) in 29 patients with relapsed or hard-to-treat blood cancers like leukemia, lymphoma, and myelofibrosis. The goal was to find the safest highest dose and see if it helps control the disease. It was a small early-phase trial at a singl…
Phase 1/2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Iron shot beats pills for new Moms' anemia?
Disease control CompletedThis study tested whether an iron injection works better than iron pills for treating anemia in 200 new mothers within 10 days of giving birth. Participants had mild to moderate anemia and were randomly assigned to receive either a single injection of ferric carboxymaltose or ora…
Phase 2/3 • Sponsor: ESI-PGIMSR, Basaidarapur • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Iron therapy showdown: daily vs. Alternate-Day for anemic kids
Disease control CompletedThis study tested whether giving oral iron every other day works as well as daily dosing for treating iron deficiency anemia in children up to 5 years old. Sixty children participated, and researchers measured changes in hemoglobin and ferritin levels. The goal was to find a simp…
Phase 3 • Sponsor: University of Child Health Sciences and Children's Hospital, Lahore • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Treadmill training boosts fitness in anemic women
Disease control CompletedThis study tested whether adding a structured treadmill walking program to standard iron therapy improves exercise tolerance and quality of life in young women with mild-to-moderate iron deficiency anemia. Sixty women aged 18-28 were split into two groups: one received iron suppl…
Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New oxygen test could cut unnecessary blood transfusions after heart surgery
Disease control CompletedThis study tested whether measuring oxygen levels in the blood (ScvO2) can help doctors decide when to give blood transfusions to anemic patients after heart surgery. 100 patients were randomly assigned to receive transfusions based on standard guidelines or only if their ScvO2 w…
Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New hope for rare blood disorder: ravulizumab trial shows promise in china
Disease control CompletedThis completed Phase 3 trial tested ravulizumab in 18 adults in China with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disorder that destroys red blood cells. The study measured changes in LDH, a marker of red blood cell breakdown, to see if the drug could control the…
Phase 3 • Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New hope for PNH patients: Long-Term drug safety confirmed
Disease control CompletedThis study tested the long-term safety of a drug called pegcetacoplan in people with PNH, a rare blood disease that destroys red blood cells. All 137 participants had already completed a prior pegcetacoplan study and continued treatment. The main goal was to track side effects ov…
Phase 3 • Sponsor: Apellis Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New drug combo shrinks spleens in bone marrow cancer patients
Disease control CompletedThis study tested a new drug called pelabresib in people with certain blood cancers, including myelofibrosis and leukemia. In the first part, the drug was given alone to find the safest dose. In the second part, it was given with or without another drug (ruxolitinib) to see if it…
Phase 1/2 • Sponsor: Constellation Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Iron pills for babies: daily or weekly? new study has answers
Disease control CompletedThis study tested whether giving iron supplements daily or weekly works better to prevent anemia in healthy Thai infants aged 6 to 12 months. A total of 287 babies were randomly assigned to receive iron daily or weekly for 3 months, then all switched to weekly for another 3 month…
Sponsor: Mahidol University • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New pill for rare blood cancers shows promise in early trial
Disease control CompletedThis early-phase study tested a new drug called TQ05105 in 79 adults with certain blood cancers (myeloproliferative neoplasms). The main goals were to find the safest dose and understand side effects. The drug works by blocking a protein (JAK2) that can cause abnormal blood cell …
Phase 1 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New pill shows promise in shrinking spleens for myelofibrosis patients
Disease control CompletedThis study tested a new drug called TQ05105 in 107 people with moderate to high-risk myelofibrosis, a rare bone marrow disorder that often causes an enlarged spleen. The goal was to see if TQ05105 could shrink the spleen better than the standard drug hydroxyurea. Participants too…
Phase 2 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New hope for PNH patients in china: eculizumab shows promise
Disease control CompletedThis study tested eculizumab in 25 adults with PNH in China who had not previously taken complement inhibitors. Participants received infusions over 62 weeks. The main goal was to see if the drug reduced LDH levels, a marker of disease activity. Results showed a decrease in LDH, …
Phase 3 • Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Experimental combo targets Hard-to-Treat blood cancers
Disease control CompletedThis early-phase study tested a new drug called TGR-1202 combined with the standard drug ruxolitinib in 60 people with myelofibrosis or polycythemia vera. The goal was to see if the combination is safe and tolerable. Participants either had not responded well to ruxolitinib alone…
Phase 1 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Gene-Editing breakthrough offers hope for blood disorder patients
Disease control CompletedThis early-stage study tested a new gene-edited stem cell transplant in 2 children with severe β-thalassemia, a serious blood disorder requiring lifelong transfusions. The treatment aims to help the body produce healthy red blood cells and reduce or stop the need for transfusions…
Early phase 1 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Rabbit antibodies show promise for rare bone marrow disease
Disease control CompletedThis phase 2 trial tested a combination of rabbit antithymocyte globulin (Thymoglobuline) and ciclosporin in 35 people with acquired aplastic anemia, a condition where the bone marrow stops making enough blood cells. The goal was to see if this rabbit-based immune-suppressing tre…
Phase 2 • Sponsor: European Society for Blood and Marrow Transplantation • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New drug shows promise in early trial for rare blood disorder
Disease control CompletedThis early study tested an experimental drug called OMS906 (zaltenibart) in 15 adults with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disease where red blood cells break apart. The main goal was to check safety and how the body handles the drug. Researchers also look…
Phase 1 • Sponsor: Omeros Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Real-World check: newer PNH drug holds up in routine care
Disease control CompletedThis study followed 120 adults with paroxysmal nocturnal hemoglobinuria (PNH) who switched from the older drug eculizumab to the newer ravulizumab. Researchers measured changes in a blood marker called LDH to see if the new drug controlled red blood cell breakdown just as well or…
Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Can a drug shorten dialysis for kids with a rare kidney disease?
Disease control CompletedThis study tested whether the drug eculizumab (Soliris) can help children with a severe kidney condition called STEC-HUS recover faster. The trial gave 100 children either eculizumab or a placebo over several weeks. The main goal was to see if the drug reduces the number of days …
Phase 3 • Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New drug may help MDS patients need fewer blood transfusions
Disease control CompletedThis study tested a drug called luspatercept in 30 adults from China and Japan who have a bone marrow disorder (MDS) and need regular red blood cell transfusions. The goal was to see if the drug could help them go without transfusions for at least 8 weeks. The drug works by helpi…
Phase 2 • Sponsor: Celgene • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Could two old drugs free thalassemia patients from lifelong transfusions?
Disease control CompletedThis phase 2 trial tested whether combining thalidomide and hydroxyurea can reduce the need for blood transfusions in people with transfusion-dependent beta thalassemia. The study enrolled 100 patients over age 2 in Pakistan, where thalassemia is common and life expectancy is low…
Phase 2 • Sponsor: Pakistan Blood and Marrow Transplant (PBMT) Group • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Promising new drug shows hope for rare anemia patients
Disease control CompletedThis study tested a drug called mitapivat (AG-348) in 52 adults with pyruvate kinase deficiency, a rare genetic condition that causes red blood cells to break down too quickly, leading to anemia. The goal was to see if different doses of the drug are safe and help control the dis…
Phase 2 • Sponsor: Agios Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New stem cell transplant approach shows promise for blood disorders
Disease control CompletedThis pilot study tested a stem cell transplant from closely matched unrelated donors for 8 patients with severe sickle cell disease or thalassemia major. The donated stem cells were specially processed to remove certain immune cells to reduce the risk of rejection and graft-versu…
Sponsor: Timothy Olson • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Can a daily powder boost iron levels in women? new study investigates
Disease control CompletedThis study tested whether a mineral-enriched powder taken daily for six months could raise blood iron levels in women aged 18-35 with iron deficiency. Participants mixed the powder or a placebo into water and provided blood samples monthly. The goal was to see if the powder reduc…
Phase 2 • Sponsor: Carleton University • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Can metformin or hydroxyurea cut transfusions for thalassemia patients?
Disease control CompletedThis completed Phase 4 trial tested two drugs—hydroxyurea and metformin—in 96 people with transfusion-dependent beta-thalassemia. Participants took one of the two drugs for a year. Researchers measured changes in fetal hemoglobin levels and how often blood transfusions were neede…
Phase 4 • Sponsor: Bahria University • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New drug combo shows promise for rare bone marrow failure
Disease control CompletedThis study tested whether adding eltrombopag to standard immunosuppressive therapy improves early recovery in patients with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. 202 participants received either standard treatment (horse a…
Phase 3 • Sponsor: European Society for Blood and Marrow Transplantation • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Could a daily pill boost blood counts in aplastic anemia?
Disease control CompletedThis study tested the drug eltrombopag in 34 people with moderate aplastic anemia, a condition where the bone marrow doesn't make enough blood cells. Eltrombopag is a pill that mimics a natural protein to stimulate blood cell production. Researchers measured whether it safely imp…
Phase 2 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New hope for kidney patients: experimental anemia drug shows promise
Disease control CompletedThis study tested a new drug called DISC-0974 in 55 adults with chronic kidney disease (not on dialysis) who also have anemia. The goal was to check the drug's safety and how the body processes it. Participants received either the drug or a placebo by injection. The results will …
Phase 1 • Sponsor: Disc Medicine, Inc • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Peanut power: could a simple supplement improve elderly health?
Disease control CompletedThis study tested whether a peanut-based nutritional supplement could improve health in adults aged 60 and older living in peri-urban Ghana. Over 12 weeks, 81 participants either took the supplement daily or served as a control group. Researchers measured weight, blood pressure, …
Phase 1 • Sponsor: University of Ghana • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Iron showdown: which anemia drug works best for kidney patients?
Disease control CompletedThis completed study looked at 128 adults with chronic kidney disease (not on dialysis) who also had iron-deficiency anemia. Researchers compared two intravenous iron treatments—ferric carboxymaltose and iron sucrose—to see which raises hemoglobin and iron levels better and with …
Sponsor: Sindh Institute of Urology and Transplantation • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New Two-Step transplant shows promise for blood cancer patients
Disease control CompletedThis study tested a two-step stem cell transplant for people with blood cancers like leukemia and lymphoma. First, patients received low-dose chemotherapy and radiation to prepare their bodies. Then, they got donor stem cells followed by drugs to prevent the donor cells from atta…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New anemia drug may cut iron needs for kidney patients
Disease control CompletedThis study compared two drugs—roxadustat and darbepoetin alfa—for treating anemia in 35 adults on hemodialysis. The goal was to see if roxadustat improves iron levels and reduces the need for IV iron. Researchers measured changes in iron profile, hemoglobin, and kidney function o…
Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New drug combo offers hope for myelofibrosis patients who failed standard therapy
Disease control CompletedThis study tested a combination of two drugs, fedratinib and nivolumab, in 30 adults with myelofibrosis whose disease no longer responded well to standard JAK-inhibitor treatment. The goal was to see if the combination could shrink the spleen, improve symptoms, or reduce the need…
Phase 2 • Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New pill could help kidney patients fight anemia without needles
Disease control CompletedThis study tested an experimental drug called MT-6548 in 42 people in Japan who have anemia due to chronic kidney disease and are on peritoneal dialysis. The goal was to see if the drug can safely raise and maintain healthy red blood cell levels. Participants either switched from…
Phase 3 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Personalized plans boost survival odds for older stem cell patients
Disease control CompletedThis study tested a personalized geriatric optimization plan (GO!) in 30 adults aged 60 and older who were getting a donor stem cell transplant for blood cancers or bone marrow failure. The plan included tailored advice on diet, sleep, activity, and medications to improve physica…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New anemia pill challenges standard shot for dialysis patients
Disease control CompletedThis study tested a new drug called MT-6548 against a standard treatment (darbepoetin alfa) for anemia in people on dialysis for chronic kidney disease. About 323 participants in Japan received either the new drug or the standard one to see if it worked as well at keeping hemoglo…
Phase 3 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Pill could replace needles for Kidney-Related anemia
Disease control CompletedThis phase 3 trial tested an oral drug called MT-6548 (vadadustat) against a standard injected drug (darbepoetin alfa) for anemia in people with chronic kidney disease who are not on dialysis. The study enrolled 304 participants in Japan to see if the oral drug is at least as goo…
Phase 3 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New pill could help dialysis patients fight anemia without needles
Disease control CompletedThis phase 3 trial tested an oral drug called vadadustat (MT-6548) in 24 Japanese adults on hemodialysis who had anemia due to chronic kidney disease. The goal was to see if the drug could raise and maintain healthy hemoglobin levels safely. Participants took the tablet daily, an…
Phase 3 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New drug combo aims to tame deadly transplant complication
Disease control CompletedThis phase II trial tested whether adding the drug itacitinib to standard medications (tacrolimus and sirolimus) can better prevent graft-versus-host disease (GVHD) in 59 patients with blood cancers receiving donor stem cell transplants. GVHD occurs when donor immune cells attack…
Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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New transplant approach shows promise for rare blood disorder
Disease control CompletedThis study tested a stem cell transplant from a half-matched family donor for people with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. The goal was to see if this approach could improve survival one year after the transplant. The tria…
Phase 2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Could a Pre-Transplant drug boost survival in myelofibrosis?
Disease control CompletedThis phase 2 trial looked at whether giving a JAK inhibitor (ruxolitinib) before a donor stem cell transplant helps people with myelofibrosis. The study enrolled 61 patients with primary or secondary myelofibrosis. The goal was to see if this approach improves survival and reduce…
Phase 2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Drug cocktail shows promise against rare bone marrow cancers
Disease control CompletedThis study tested a combination of two drugs, ruxolitinib and azacytidine, in 121 people with myelofibrosis or related blood cancers. The goal was to see if the combo could shrink tumors or improve blood counts. While the treatment aims to control the disease, it is not a cure, a…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New drug shows promise for preventing severe anemia in unborn babies
Disease control CompletedThis study tested an experimental drug called M281 (nipocalimab) in 25 pregnant women at high risk for early-onset severe hemolytic disease of the fetus and newborn (HDFN), a condition where the mother's immune system attacks the baby's red blood cells. The goal was to see if the…
Phase 2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New combo therapy aims to shrink spleens in bone marrow cancer patients
Disease control CompletedThis study tested whether adding the experimental drug navitoclax to the standard drug ruxolitinib works better than ruxolitinib alone for people with myelofibrosis, a type of bone marrow cancer. The main goal was to see if the combination could shrink an enlarged spleen by at le…
Phase 3 • Sponsor: AbbVie • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New transplant cocktail aims to cut complications in bone marrow failure
Disease control CompletedThis phase 2 trial tested a combination of treosulfan, fludarabine, and rabbit antithymocyte globulin before a bone marrow transplant in 40 people with bone marrow failure diseases like Diamond-Blackfan anemia and Shwachman-Diamond syndrome. The goal was to see if this conditioni…
Phase 2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Super millet: could a fortified grain fight nutrient deficiencies in kids?
Disease control CompletedThis study gave 223 children aged 12-18 months in India either iron- and zinc-biofortified pearl millet or regular pearl millet for 9 months. Researchers measured changes in iron levels, growth, and immune responses. The goal was to see if this enriched grain could help prevent c…
Sponsor: Cornell University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New program aims to cut blood transfusions in heart surgery
Disease control CompletedThis study looked at ways to reduce the need for blood transfusions in patients having planned heart surgery with a heart-lung machine. The researchers tested two approaches: improving how doctors decide to give transfusions and treating low iron and anemia before and after surge…
Sponsor: Clinique Pasteur • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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One donor, two transplants: could this end lifelong Anti-Rejection drugs?
Disease control CompletedThis pilot study tested a combined bone marrow and kidney transplant from a partially matched family donor in 10 people with both a blood disorder and chronic kidney disease. The goal was to treat both conditions at once and possibly reduce the need for lifelong anti-rejection dr…
Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Experimental cell therapy offers hope for Hard-to-Treat blood disorder
Disease control CompletedThis early-phase study tested a new cell therapy called YTS109 in 7 people with a severe type of autoimmune anemia that did not get better after at least 3 other treatments. The therapy uses specially engineered immune cells to target and destroy the faulty cells causing the dise…
Phase 1 • Sponsor: China Immunotech (Beijing) Biotechnology Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New combo treatment shows promise for kids with rare bone marrow failure
Disease control CompletedThis study reviewed medical records of 13 Korean children with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. Researchers wanted to see if adding eltrombopag to standard immunosuppressive therapy was safe and effective. Over 6 months, t…
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Gene editing offers hope for blood disorder patients
Disease control CompletedThis early-phase study tested a new gene-edited stem cell treatment (CS-101) in 5 people with beta-thalassemia, a severe blood disorder requiring regular blood transfusions. The goal was to see if the treatment is safe and can help patients produce healthy red blood cells, potent…
Early phase 1 • Sponsor: CorrectSequence Therapeutics Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New pill shows promise for PNH patients still anemic on standard therapy
Disease control CompletedThis study tested a new tablet called HSK39297 in 36 adults with paroxysmal nocturnal hemoglobinuria (PNH) who still had anemia despite stable treatment with anti-C5 antibodies. The goal was to see if the pill could raise hemoglobin levels and reduce the need for blood transfusio…
Phase 3 • Sponsor: Haisco Pharmaceutical Group Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New 9-Day combo shows promise for rare bone marrow disease
Disease control CompletedThis study tested a new 9-day treatment plan for people with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. The treatment combines three drugs (rabbit antithymocyte globulin, cyclosporine, and levamisole) to suppress the immune sys…
Phase 2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Laser surgery or watchful waiting? trial seeks best care for twin syndrome
Disease control CompletedThis trial compared two approaches for twin-to-twin transfusion syndrome (TTTS) stage 1: immediate laser surgery versus careful observation. 179 pregnant women with TTTS stage 1 and favorable conditions took part. The goal was to see which strategy leads to better survival and br…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New hope for rare anemia: drug combo shows promise
Disease control CompletedThis phase 2 trial tested a combination of two drugs, bortezomib and dexamethasone, in 18 adults with acquired pure red cell aplasia whose disease did not improve or came back after first treatment. The goal was to see if the combination could safely control the condition. The st…
Phase 2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New stem cell therapy aims to free patients from lifelong blood transfusions
Disease control CompletedThis study tested a new treatment called ET-01 in 3 people with transfusion-dependent beta-thalassemia, a blood disorder that requires regular blood transfusions. The treatment uses the patient's own stem cells, which are modified and then transplanted back. The goal was to see i…
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Gene therapy breakthrough? early trial for blood disorder shows promise
Disease control CompletedThis early-stage study tested a single dose of a gene therapy called CS-101 in 9 people with beta-thalassemia major, a severe blood disorder requiring lifelong transfusions. The main goals were to check safety and see if the treatment helps the body make more healthy hemoglobin. …
Phase 1 • Sponsor: CorrectSequence Therapeutics Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Iron showdown: IV or pills for anemia in pregnancy?
Disease control CompletedThis completed Phase 1 trial tested whether a single IV dose of ferric carboxymaltose works better than daily oral polysaccharide iron complex capsules for treating iron deficiency anemia in pregnant women. 112 women in their second trimester with low hemoglobin levels took part.…
Phase 1 • Sponsor: Dr Salaha Azam • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Cord blood transfusions show promise for tiniest babies
Disease control CompletedThis study tested whether red blood cells from umbilical cord blood are safe and work as well as standard adult donor blood for transfusions in extremely preterm infants (born before 28 weeks). 41 babies received small transfusions, and researchers monitored their vital signs, ox…
Sponsor: Hospital Clinic of Barcelona • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Cash and iron: a new recipe to fight anemia in pakistani teens?
Disease control CompletedThis study tested whether giving weekly iron and folic acid supplements along with nutrition education and a small cash payment to mothers could reduce anemia in adolescent girls in flood-affected areas of Pakistan. Over 2,100 girls aged 15-19 took part. The goal was to see if th…
Sponsor: Aga Khan University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Weekly shot could replace daily insulin for thalassemia kids with diabetes
Disease control CompletedThis study tested a once-weekly injection called dulaglutide (a GLP-1 drug) against daily insulin in 80 children aged 10-18 with transfusion-dependent thalassemia and diabetes. The goal was to see if the weekly shot could control blood sugar just as well or better than insulin ov…
Phase 2 • Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New drug shows promise for anemia in diabetic kidney patients
Disease control CompletedThis study looked at how well the drug Roxadustat works for anemia in people with diabetic kidney disease stages 3-4. 124 participants took the drug for 24 weeks, and researchers measured changes in hemoglobin and iron levels. The goal was to see if the drug can safely raise red …
Phase 4 • Sponsor: Second Xiangya Hospital of Central South University • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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New hope for myelofibrosis patients: drug combo shows promise in shrinking spleens
Disease control CompletedThis study tested a drug called navitoclax, either alone or added to the standard drug ruxolitinib, in 191 people with myelofibrosis. The main goal was to see if the treatment could shrink the spleen by at least 35% after 24 weeks. The trial also looked at whether it could reduce…
Phase 2 • Sponsor: AbbVie • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New IV iron shows promise for speedy anemia recovery after surgery
Disease control CompletedThis study tested three types of iron supplements in 187 adults who had low iron before major surgery and developed anemia after it. The goal was to see which treatment—two different IV iron formulas or oral iron pills—worked best to quickly raise hemoglobin levels. The results h…
Phase 3 • Sponsor: Prof. Dr. Frank Behrens • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Diabetes drug shows promise for kidney and heart health in Non-Diabetic patients
Disease control CompletedThis study tested whether dapagliflozin, a drug typically used for diabetes, can slow kidney decline, improve anemia, and support heart health in 100 adults with chronic kidney disease who do not have diabetes. Participants took either the drug or a placebo daily for 12 months al…
Phase 3 • Sponsor: Mansoura University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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New PNH pill matches standard infusion therapy in trial
Disease control CompletedThis study tested an oral medication called iptacopan in 52 adults with Paroxysmal Nocturnal Hemoglobinuria (PNH) who were already stable on standard infusion treatments. Participants switched from their usual therapy to iptacopan pills taken twice daily. The main goal was to see…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New drug combo shows promise for rare blood disorder
Disease control CompletedThis study tested whether adding eltrombopag (a platelet booster) to standard immune-suppressing drugs (r-ATG and cyclosporine A) helps patients with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. Thirty-six East-Asian adults and c…
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New oral drug HRS-5965 shows promise for tough PNH anemia cases
Disease control CompletedThis phase 3 trial tested a new drug called HRS-5965 in 39 adults with paroxysmal nocturnal hemoglobinuria (PNH) who remained anemic even after standard anti-C5 antibody treatment. The study aimed to see if the drug could raise hemoglobin levels without needing blood transfusions…
Phase 3 • Sponsor: Chengdu Suncadia Medicine Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Iron showdown: IV vs pills after heart attack
Disease control CompletedThis study tested whether giving iron through a vein (IV) works better than iron pills for improving heart pumping function in people who recently had a heart attack and also have low iron. About 300 adults took part, receiving either IV iron or oral iron. The main goal was to se…
Sponsor: Kazan State Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Sickle cell hope: drug combo raises hemoglobin in early trial
Disease control CompletedThis study tested whether adding erythropoietin (EPO) to the standard drug hydroxyurea can safely raise hemoglobin levels in adults with sickle cell disease. Seventeen participants with chronic anemia took both drugs for 12 weeks. The main goal was to see if at least a 1.0 g/dL i…
Phase 1/2 • Sponsor: Julia Xu • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Iron study: Every-Other-Day dosing may boost absorption
Disease control CompletedThis study tested whether taking oral iron every second day at double the standard dose helps people with iron deficiency absorb more iron and raise their hemoglobin faster than taking it daily. 29 adults with low iron but not severe anemia participated for 12 weeks. Researchers …
Phase 4 • Sponsor: Luzerner Kantonsspital • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Lower chemo dose may prevent transplant complications
Disease control CompletedThis study tested whether a low dose of the drug cyclophosphamide, given after a stem cell transplant, can prevent graft-versus-host disease (GVHD) — a common and serious complication where donor cells attack the patient's body. The trial involved 35 adults with various blood dis…
Phase 2 • Sponsor: Hospital Universitario Dr. Jose E. Gonzalez • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Can a simple iron infusion before heart surgery speed up recovery?
Disease control CompletedThis study tested whether giving an intravenous iron infusion to anemic patients before elective heart surgery helps them recover faster. Nearly 1,000 adults with anemia received either IV iron or a placebo 1 to 10 weeks before their surgery. The main goal was to see if the iron …
Phase 4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Drug dasatinib tested for rare blood cancers
Disease control CompletedThis study tested the drug dasatinib in 68 adults with several types of blood and bone marrow disorders, including certain leukemias, myelofibrosis, and mastocytosis. The goal was to see if dasatinib could help control the disease and to check its safety. Participants took dasati…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New hope for tough anemia: drug boosts blood cells in failed cases
Disease control CompletedThis study tested a drug called eltrombopag in 20 Chinese adults with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. Participants had not responded to previous treatments. The drug was given daily for up to a year to see if it could imp…
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Money and support groups boost HIV care in kenya
Disease control CompletedThis study tested a program that combines small loans and group support to help people with HIV in Kenya. The goal was to improve HIV medication adherence, mental health, and family relationships. 843 people took part, and the program aimed to reduce depression, anxiety, and PTSD…
Sponsor: The University of Texas Medical Branch, Galveston • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New pill shows promise for rare blood disorder in phase 3 trial
Disease control CompletedThis study tested a new pill called HSK39297 against a standard infusion drug (eculizumab) in 73 adults with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disorder that destroys red blood cells. Participants had not received prior complement inhibitor treatment. The mai…
Phase 3 • Sponsor: Haisco Pharmaceutical Group Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New pill could cut blood transfusions for blood disorders
Disease control CompletedThis Phase 2 study tested an experimental drug called etavopivat in 53 people with thalassemia or sickle cell disease. The goal was to see if the pill could safely reduce the number of red blood cell transfusions needed and raise hemoglobin levels. Participants took 400 mg of eta…
Phase 2 • Sponsor: Forma Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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CRISPR gene editing offers hope for thalassemia patients to ditch transfusions
Disease control CompletedThis study tested a single treatment using CRISPR gene editing to modify a person's own blood stem cells, aiming to help people with severe beta-thalassemia stop needing regular blood transfusions. 59 participants received the therapy and were monitored for safety and how long th…
Phase 2/3 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Drug duo shows promise for Tough-to-Treat leukemia
Disease control CompletedThis phase II trial tested two drugs—sirolimus and azacitidine—in 57 people with high-risk myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that had come back or didn't respond to standard treatment. The goal was to see if the combination could shrink or control the…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New hope for rare blood disorder: Long-Term drug study shows promise
Disease control CompletedThis study looked at the long-term safety and effectiveness of the drug mitapivat in 90 adults with pyruvate kinase deficiency, a rare genetic blood disorder that causes red blood cells to break down too quickly. Participants had already completed earlier studies of mitapivat and…
Phase 3 • Sponsor: Agios Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Blood transfusion showdown: can more red cells save preemie brains?
Disease control CompletedThis study looked at whether giving more red blood cell transfusions (liberal strategy) to extremely low birth weight babies (under 1000 grams) helps them survive without brain damage compared to a more restrictive approach. Over 1800 infants from NICUs were followed until 22-26 …
Sponsor: NICHD Neonatal Research Network • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New iron supplement may be kinder to Kids' stomachs
Disease control CompletedThis study tested a new iron supplement called ferric maltol (given as an oral suspension) against the standard ferrous sulfate liquid in children aged 2 to 17 with iron-deficiency anaemia, and also tested ferric maltol alone in infants aged 1 month to 2 years. The goal was to se…
Phase 3 • Sponsor: Shield Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New pill shows promise for anemia in kids with kidney disease
Disease control CompletedThis study tested a drug called daprodustat in children aged 3 months to under 18 years who have anemia due to chronic kidney disease. The goal was to see how the drug moves through the body and if it is safe. Only 4 children took part, and they received the drug for up to 52 wee…
Phase 3 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New Two-Step transplant shows promise for tough blood cancers
Disease control CompletedThis study tested a two-step stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. First, patients got low-dose chemotherapy and radiation to prepare the body. Then, they received donor stem cells and immune cells to help destroy remaining cance…
Phase 2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New drug shows promise for rare blood disorder
Disease control CompletedThis study tested a drug called pegcetacoplan in 24 adults with cold agglutinin disease, a rare condition where the immune system destroys red blood cells. Participants received either the drug or a placebo twice a week for 24 weeks. The goal was to see if the drug could raise he…
Phase 3 • Sponsor: Swedish Orphan Biovitrum • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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15-Minute iron shot could beat anemia fast
Disease control CompletedThis completed trial tested a single 15-minute infusion of ferumoxytol, a type of intravenous iron, in 60 people with iron deficiency anemia who couldn't take oral iron. The goal was to see if this quick dose safely raises hemoglobin levels. Researchers checked for side effects r…
Sponsor: Auerbach Hematology Oncology Associates P C • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Glutamine shows promise for thalassemia lung complication
Disease control CompletedThis small study tested whether L-glutamine, a common supplement, can reduce high blood pressure in the lungs of adults with non-transfusion-dependent thalassemia. Eight participants took either glutamine plus standard care or standard care alone for 60 days. The main goal was to…
Phase 2/3 • Sponsor: Mazandaran University of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New pill shows promise for rare blood cancer in early trial
Disease control CompletedThis early-phase trial tested a new drug called flonoltinib maleate in 31 people with myeloproliferative neoplasms (MPNs), a group of bone marrow cancers. The main goals were to check safety, find the right dose, and see how the body processes the drug. Researchers hope this drug…
Phase 1/2 • Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New hope for PNH patients: experimental drug OMS906 shows promise in early trial
Disease control CompletedThis study tested a new drug called OMS906 in 12 adults with paroxysmal nocturnal hemoglobinuria (PNH) who were not getting enough benefit from the standard treatment ravulizumab. The goal was to see if OMS906 is safe and can improve hemoglobin levels. Participants received OMS90…
Phase 2 • Sponsor: Omeros Corporation • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Daily vitamin d may slash lung risks in kids with sickle cell disease
Disease control CompletedThis study tested whether taking vitamin D every day could reduce lung complications in children and teens with sickle cell disease. Lung problems like infections, asthma attacks, and acute chest syndrome are major causes of illness and death in this condition. Researchers gave d…
Phase 2 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New transplant recipe may tame severe anemia
Disease control CompletedThis study reviews a modified transplant conditioning regimen for severe aplastic anemia in 72 patients across two hospitals. The approach uses a combination of fludarabine, melphalan, and cyclophosphamide to prepare the body for a stem cell transplant. Researchers looked at how …
Sponsor: Hematology department of the 920th hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New drug BIVV020 tested for rare blood disorder
Disease control CompletedThis early-stage trial tested a single dose of the drug BIVV020 in 12 adults with cold agglutinin disease, a rare condition where the immune system mistakenly attacks red blood cells. The main goal was to see if the drug is safe and tolerable. Researchers also looked at how it af…
Phase 1 • Sponsor: Bioverativ, a Sanofi company • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Bomedemstat extension trial tests Long-Term safety for blood cancer patients
Disease control CompletedThis study looks at the long-term safety of bomedemstat, an oral drug, in 81 people with myeloproliferative neoplasms (MPNs) like essential thrombocythemia and primary myelofibrosis. Participants had already taken bomedemstat in a prior study. Researchers tracked side effects, sp…
Phase 2 • Sponsor: Imago BioSciences, Inc., a subsidiary of Merck & Co., Inc., (Rahway, New Jersey USA) • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Can boosting hemoglobin help kidney transplant patients feel better and protect their kidneys?
Disease control CompletedThis study looked at whether raising hemoglobin levels with a drug called epoetin (Neorecormon) could improve quality of life and slow kidney function decline in people who had a kidney transplant and now have chronic graft dysfunction. About 128 adults who had a transplant 1 to …
Phase 4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Can a cheap iron syrup before surgery save kids from anemia risks?
Disease control CompletedThis study looked at whether giving children with iron-deficiency anemia oral iron for 6 to 12 weeks before elective surgery can raise their hemoglobin levels. Researchers enrolled 755 children in South Africa to test this simple, low-cost approach. The goal is to see if treating…
Phase 4 • Sponsor: University of Cape Town • Aim: Disease control
Last updated Jun 26, 2026 18:19 UTC
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New drug combo shows promise for rare blood disorder
Disease control CompletedThis phase 2 trial tested whether adding luspatercept to standard cyclosporine treatment helps people with non-severe aplastic anemia. The study enrolled 58 newly diagnosed adults who had low blood counts but did not yet need transfusions. The goal was to see if the combination c…
Phase 2 • Sponsor: Bing Han • Aim: Disease control
Last updated Jun 26, 2026 17:44 UTC
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Can a simple iron pill fix low hemoglobin in blood donors?
Disease control CompletedThis pilot study looked at whether taking an iron supplement called sucrosomial iron for three months can raise hemoglobin levels in blood donors who have iron deficiency. Fifty donors with low iron took the supplement daily. Researchers measured changes in hemoglobin, ferritin, …
Sponsor: Medical University of Graz • Aim: Disease control
Last updated Jun 26, 2026 17:43 UTC
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Japanese CAD patients get continued access to experimental drug sutimlimab
Disease control CompletedThis study gave sutimlimab to 7 adults in Japan with cold agglutinin disease (CAD) who had already completed earlier trials and still needed treatment. The goal was to monitor safety and side effects over time until the drug became commercially available. It is a small, open-labe…
Phase 3 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 26, 2026 17:23 UTC
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Can a yeast drink boost iron and glow? small study tests it
Disease control CompletedThis small study tested whether a daily iron-rich yeast drink with SOD can improve anemia and skin condition in women aged 18-35. Eleven women with mild anemia drank the supplement for four weeks. Researchers measured blood iron levels and skin-related markers before and after to…
Sponsor: Hangzhou Agile Groups Network Technology Co., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 17:03 UTC
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Rural india pregnancy trial tests simple screening to save mothers
Disease control CompletedThis trial tested a program where community health workers used a tablet app to screen pregnant women in rural India for anemia, high blood pressure, and diabetes. Over 3,400 women took part. The goal was to see if this screening and referral system could lower anemia rates and i…
Sponsor: The George Institute • Aim: Disease control
Last updated Jun 26, 2026 16:55 UTC
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Anemia drug MIRCERA studied in kidney patients before dialysis
Disease control CompletedThis study looked at how well MIRCERA works for anemia in people with chronic kidney disease stages 3-4 who are not yet on dialysis. Researchers tracked 144 patients over 12 months to see if their hemoglobin levels stayed in a healthy range. The goal was to gather real-world data…
Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 26, 2026 16:55 UTC
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Once-a-Month shot could ease anemia for kidney patients
Disease control CompletedThis study tested a monthly injection of Mircera in 75 adults with chronic kidney disease who were not yet on dialysis and had anemia. The goal was to see if the drug could safely raise and maintain hemoglobin levels. Results showed improvement in hemoglobin during the evaluation…
Phase 3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 26, 2026 16:43 UTC
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New blood treatment could make transfusions safer for heart surgery
Disease control CompletedThis study tested a special way to treat donated red blood cells to kill germs, called the INTERCEPT Blood System. It involved 581 people having complex heart surgery who needed blood transfusions. The goal was to see if this treated blood is as safe and works as well as regular …
Phase 3 • Sponsor: Cerus Corporation • Aim: Disease control
Last updated Jun 26, 2026 16:32 UTC
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New pill could rival standard infusion for rare blood disorder
Disease control CompletedThis Phase 3 study tested a new oral medication, HRS-5965, against the standard infusion eculizumab in 76 adults with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disorder. The main goal was to see if HRS-5965 could raise hemoglobin levels to normal without needing blo…
Phase 3 • Sponsor: Chengdu Suncadia Medicine Co., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 16:17 UTC
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New monthly shot could simplify anemia treatment for kidney patients
Disease control CompletedThis study tested whether a once-monthly injection of Mircera works as well as the standard epoetin alfa treatment for managing anemia in people on dialysis. About 233 adults with chronic kidney disease-related anemia participated. The goal was to see if Mircera could keep hemogl…
Phase 3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 26, 2026 16:06 UTC
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Iron showdown: which infusion works best for anemic Moms-to-Be?
Disease control CompletedThis study compared two intravenous iron treatments—ferric carboxymaltose and iron sucrose—in 40 pregnant women with anemia. The goal was to see which one raised hemoglobin levels more. Both are already used in practice, but local data was lacking. The trial is now complete, and …
Sponsor: Muhammad Aamir Latif • Aim: Disease control
Last updated Jun 26, 2026 13:55 UTC
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Gene therapy offers hope for rare blood disorder
Disease control CompletedThis phase 1 trial tested a gene therapy called RP-L301 in 4 people with pyruvate kinase deficiency, a rare inherited blood disorder that causes severe anemia and often requires frequent blood transfusions. The treatment uses the patient's own blood stem cells, which are modified…
Phase 1 • Sponsor: Rocket Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 26, 2026 13:53 UTC
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New drug itacitinib tested for Hard-to-Treat myelofibrosis
Disease control CompletedThis phase 2 study tested the drug itacitinib in 4 people with myelofibrosis (a bone marrow disorder) who had already tried other treatments like ruxolitinib or fedratinib. The main goals were to check safety and find the right dose, and to see if it could shrink an enlarged sple…
Phase 2 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Jun 26, 2026 13:11 UTC
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Can a Finger-Prick blood test reveal hidden malaria in the placenta?
Diagnosis CompletedMalaria in pregnancy can hide in the placenta and harm both mother and baby, yet it often goes undetected. This study enrolls about 1,200 pregnant women in Africa to see whether malaria rapid diagnostic tests, blood smears, and PCR on maternal blood can accurately detect or predi…
Sponsor: Foundation for Innovative New Diagnostics, Switzerland • Aim: Diagnosis
Last updated Sep 19, 2026 00:00 UTC
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New MRI scan could replace liver biopsies for iron overload patients
Diagnosis CompletedThis study tested a new MRI technique called QSM to measure iron levels in the liver more accurately than current methods. Researchers compared MRI results from 55 patients before liver transplant with chemical analysis of their removed livers. The goal is to improve diagnosis an…
Sponsor: Weill Medical College of Cornell University • Aim: Diagnosis
Last updated Jun 27, 2026 09:09 UTC
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AI camera could replace needles for anemia screening in kids
Diagnosis CompletedThis completed study tested whether artificial intelligence can estimate iron deficiency and anemia risk in African children without a blood draw. Researchers collected blood samples, images, and videos from 126 children under 6 years old to train AI algorithms. The goal is to de…
Sponsor: Danone Asia Pacific Holdings Pte, Ltd. • Aim: Diagnosis
Last updated Jun 27, 2026 09:01 UTC
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No more needles? new study tests Light-Based hemoglobin monitoring in Kids' brain surgery
Diagnosis CompletedThis study tested whether a non-invasive device that uses light (pulse co-oximetry) can accurately measure hemoglobin levels in children undergoing brain or spine surgery, compared to the standard method of drawing blood from an artery. The goal was to see if this painless, conti…
Sponsor: Selcuk University • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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Simple blood tests may spot liver damage in thalassemia kids
Diagnosis CompletedThis study looked at 100 children with beta-thalassemia major and iron overload to see if simple blood tests (ferritin and hepcidin) can detect liver scarring (fibrosis) as accurately as other non-invasive methods. Researchers measured these blood markers and compared them to ult…
Sponsor: Tanta University • Aim: Diagnosis
Last updated Jun 26, 2026 14:15 UTC
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Can a simple preventive drug cut malaria and anemia in infants?
Prevention CompletedThis trial tests whether giving infants a preventive dose of the antimalarial drug sulfadoxine-pyrimethamine during routine health visits can lower their risk of malaria and anemia. Researchers will follow about 2,100 children in Cameroon, comparing those in areas receiving this …
Sponsor: London School of Hygiene and Tropical Medicine • Aim: Prevention
Last updated Sep 10, 2026 00:00 UTC
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Can scheduled malaria drugs shield infants from severe illness?
Prevention CompletedThis trial tests whether giving infants in Côte d'Ivoire a preventive dose of an antimalarial drug at routine health visits can lower their risk of malaria and anemia. Researchers will compare outcomes for infants in areas receiving this intervention against those receiving stand…
Sponsor: London School of Hygiene and Tropical Medicine • Aim: Prevention
Last updated Sep 10, 2026 00:00 UTC
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Ancient heat therapy tested to prevent post-transplant bladder pain
Prevention CompletedThis study tests whether moxibustion, a traditional therapy that burns herbs near the skin, can prevent hemorrhagic cystitis (painful bladder inflammation) in 266 patients receiving stem cell transplants. Participants are randomly assigned to receive either standard care or stand…
Sponsor: Yi Zhang • Aim: Prevention
Last updated Aug 26, 2026 00:00 UTC
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School-Based malaria prevention could shield entire villages
Prevention CompletedThis study tests whether giving school children preventive malaria medicine can reduce infections not only in them but also in younger siblings at home. About 1,000 students in rural Malawi will receive either one of two drug combinations or no preventive treatment. Researchers w…
Phase 4 • Sponsor: Liverpool School of Tropical Medicine • Aim: Prevention
Last updated Aug 01, 2026 00:00 UTC
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Could a natural compound help prevent cancer in a rare disease?
Prevention CompletedThis study tested whether quercetin, a natural substance found in some foods, could help prevent a type of mouth cancer in people with Fanconi anemia, a rare genetic condition that raises cancer risk. 48 participants took quercetin to see if it reduced certain cell changes linked…
Phase 2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Prevention
Last updated Jun 27, 2026 12:10 UTC
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Milk protein may shield obese moms from anemia
Prevention CompletedThis study tested whether taking a daily supplement of lactoferrin (a protein found in milk) can help prevent iron deficiency anemia in pregnant women with obesity. 23 women at risk for anemia took part from mid-pregnancy through labor. The main goal was to see if the approach wa…
Sponsor: University of Illinois at Chicago • Aim: Prevention
Last updated Jun 27, 2026 09:05 UTC
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Simple vitamin pills could cut blood transfusions in pregnant african women
Prevention CompletedThis study tested whether adding daily multivitamins and an extra dose of deworming medication to standard prenatal care could prevent severe anemia in pregnant women in Zanzibar, Tanzania. Over 2,500 pregnant women took part, comparing the enhanced package to the usual WHO-recom…
Phase 3 • Sponsor: Cornell University • Aim: Prevention
Last updated Jun 27, 2026 09:04 UTC
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Can IV iron prevent anemia in pregnant women?
Prevention CompletedThis study tested whether giving intravenous iron to pregnant women who have low iron stores but not yet anemia can prevent them from becoming anemic and help their babies grow normally. 600 women took part. The goal is to see if a single IV dose works better than usual care.
Phase 4 • Sponsor: Services Institute of Medical Sciences, Pakistan • Aim: Prevention
Last updated Jun 27, 2026 08:11 UTC
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Iron shot boosts heart Patients' stamina, study hopes
Symptom relief CompletedThis study tests whether a single dose of intravenous iron (ferric derisomaltose) can improve exercise capacity in people with heart failure with preserved ejection fraction who also have iron deficiency. About 66 adults will receive either the iron infusion or a placebo, and the…
Phase 2/3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Sep 06, 2026 00:00 UTC
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Can heated herb plasters boost blood counts after chemotherapy?
Symptom relief CompletedThis trial tests whether heated traditional Chinese medicine plasters can help cancer patients recover from chemotherapy-induced anemia and low blood cell counts. Participants apply the plaster to a specific point on the navel for one hour daily over two weeks. Researchers compar…
Sponsor: Hung-Rong Yen • Aim: Symptom relief
Last updated Aug 29, 2026 00:00 UTC
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Could carbon monoxide be a medicine? new trial for sickle cell
Symptom relief CompletedThis study tests a new liquid drug called HBI-002, which contains carbon monoxide, in 9 people with sickle cell disease aged 14 to 55. Participants take the drug daily for 14 days to see if it is safe and helps with symptoms. The goal is to find a better way to manage this painfu…
Phase 2 • Sponsor: Hillhurst Biopharmaceuticals, Inc. • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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Can a computer program tame sickle cell pain crises?
Symptom relief CompletedThis trial tests a computer-based tool called PAINRelieveIt for adults with sickle cell disease, a condition that causes intense pain episodes. The tool has three parts: one helps patients report their pain, another educates them about pain management, and a third helps doctors c…
Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Iron boost after heart valve procedure shows promise in small trial
Symptom relief CompletedThis study looked at whether a single intravenous iron dose could improve exercise capacity in people with severe aortic stenosis and iron deficiency who were scheduled for a valve replacement. About 100 participants received either iron or a placebo. The main goal was to see if …
Phase 2 • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Could iron pills ease ADHD and restless legs in children?
Symptom relief CompletedThis study looked at whether giving iron supplements to children with ADHD, restless legs syndrome, and low iron levels could improve their symptoms. Twelve kids aged 10-15 took iron for 3 months. Researchers measured changes in brain iron, blood iron, and symptoms using sleep mo…
Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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New study aims to crack the code of autoimmune diseases
Knowledge-focused CompletedThis study is collecting blood, urine, and stool samples from 500 children with autoimmune diseases and healthy controls. Researchers will analyze these samples to find molecular patterns that could help diagnose these conditions and guide treatment decisions. The goal is to crea…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC
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Pens and vouchers: can small rewards boost participation in blood cancer research?
Knowledge-focused CompletedResearchers want to learn what causes myeloproliferative neoplasms, a group of rare blood cancers. They are testing whether small incentives like pens, trolley tokens, or a £10 reimbursement encourage more people to join a case-control study. The trial includes about 100 patients…
Sponsor: Queen's University, Belfast • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC
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Neighborhood chats may help overcome COVID-19 testing mistrust
Knowledge-focused CompletedThis study tested whether weekly community-led group discussions about health topics could change how people feel about COVID-19 testing and vaccines. 49 adults from housing authority agencies took part in Zoom meetings and completed surveys over 18 weeks. The goal was to see if …
Sponsor: Old Dominion University • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC
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Can these supplements boost nutrient absorption in chronic illness?
Knowledge-focused CompletedThis study is testing whether two dietary supplements, Goodphyte IB Defense and Goodphyte Immunity, are acceptable and easy for adults with chronic diseases like IBD, hypertension, anemia, or multiple sclerosis to take. Researchers will also check if the supplements improve how w…
Sponsor: University of Thessaly • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Can a simple blood test predict surgery risks?
Knowledge-focused CompletedThis study asks whether having anemia before major gastrointestinal surgery leads to more complications afterward. Researchers will follow 146 adults in Greece who undergo open or laparoscopic GI surgery, tracking any complications until discharge or day 8 after surgery. They wil…
Sponsor: University of Ioannina • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Does seeing a doctor shake your trust in AI? new study investigates
Knowledge-focused CompletedThis study tracks 180 orthopedic patients in Cyprus to see if a single doctor visit changes how much they trust AI health information. Patients fill out surveys before and after their appointment, and doctors also report on the accuracy of any AI advice patients brought up. The g…
Sponsor: Utku Gürhan • Aim: Knowledge-focused
Last updated Sep 02, 2026 00:00 UTC
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Can a cancer drug curb severe bleeding in a rare genetic disorder?
Knowledge-focused CompletedThis study looks back at the medical records of 244 adults in France with hereditary hemorrhagic telangiectasia (HHT), also called Rendu-Osler disease, who were treated with the drug bevacizumab. The goal is to describe how the drug was used and to measure its impact on bleeding,…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Blood test may spare cancer patients unneeded iron infusions
Knowledge-focused CompletedThis trial explores whether a blood test measuring reticulocyte hemoglobin content (RET-He) can predict how well cancer patients with anemia will respond to intravenous iron treatment. The study involves adults with solid tumors who have functional iron deficiency. By checking RE…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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Local cereals fortified with vitamins could boost teen health in rural ethiopia
Knowledge-focused CompletedThis study looked at whether adding folic acid and vitamin B12 to locally made cereals can improve the nutrition, thinking skills, and mood of teenage girls in rural Ethiopia. About 472 girls aged 13-19 took part. The goal was to see if small-scale food fortification can help pre…
Sponsor: University Ghent • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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A simple blood test trend may flag ICU patients at risk
Knowledge-focused CompletedThis observational study looks at whether a fast drop in hemoglobin during the first 24 hours in the ICU can predict a longer stay (8 days or more) or death in the hospital. Researchers will review medical records of about 128 critically ill adults, comparing their hemoglobin lev…
Sponsor: Hospital H+ Queretaro • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Could a platelet-boosting drug shorten recovery after stem cell transplants?
Knowledge-focused CompletedThis study looks back at medical records of people who had an allogeneic stem cell transplant to see whether romiplostim helped their platelets recover faster. Platelets are blood cells that help clotting, and low counts are common after transplant. The researchers will compare p…
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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Scientists track red blood cell lifespan to solve anemia mystery in seniors
Knowledge-focused CompletedThis study looked at why many older adults (over 70) have anemia even when doctors can't find a reason. Researchers measured how long red blood cells live in younger and older adults by marking them with a vitamin called Biotin. The goal was to understand if faster red blood cell…
Phase 1 • Sponsor: National Institute on Aging (NIA) • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Scientists hunt for genetic roots of rare childhood blood disorder
Knowledge-focused CompletedThis study investigates the genetic causes of pediatric Evans syndrome, a rare autoimmune condition where the immune system attacks blood cells. Researchers analyze blood samples from affected children and their families to find known or new mutations. The goal is to better under…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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No treatment, just observation: large study looks at PNH blood cells
Knowledge-focused CompletedThis completed study looked at red and white blood cells in people with a rare blood disorder called PNH who also have bone marrow failure. Over 5,500 participants aged 10 and older with aplastic anemia or related conditions provided blood samples. The goal was simply to learn mo…
Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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New study aims to unlock the secrets of Children's rare blood diseases
Knowledge-focused CompletedThis study follows children in France diagnosed with severe autoimmune cytopenia—conditions where the immune system attacks blood cells. Researchers will track their health over time to see who achieves remission and what factors influence their recovery. The goal is to better un…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Weighty issue: does obesity block iron supplements?
Knowledge-focused CompletedThis study examined the link between obesity and iron deficiency anemia in 165 nonpregnant Indonesian women aged 19-29. Participants took daily iron-folic acid supplements for 90 days. Researchers compared iron levels between overweight/obese and normal-weight women to see if wei…
Sponsor: Griffith University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Hidden deficiencies in black college athletes under the microscope
Knowledge-focused CompletedThis pilot study investigates how common low energy availability, iron deficiency, and low vitamin D levels are among Black collegiate athletes. Participants who are found to have low iron or vitamin D will receive daily supplements for 12 weeks. The goal is to better understand …
Sponsor: Morehouse School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Plant-Derived heme iron: a new way to fight iron deficiency?
Knowledge-focused CompletedThis study looked at how well iron-deficient women absorb iron from two plant-based sources—iron chlorophyllin and soy hemoglobin—compared to standard ferrous sulfate and animal-based heme iron. Forty-five women with low iron stores but not anemic took each type of iron in water …
Sponsor: ETH Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Study probes link between transfusions and gut trouble in preterm infants
Knowledge-focused CompletedThis completed study looked at 324 extremely low birth weight preterm infants (≤1250 grams) to see how anemia and red blood cell transfusions affect oxygen levels in their digestive tract. Researchers used a non-invasive device to measure tissue oxygen and collected blood, urine,…
Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Scientists probe the root cause of a rare bone marrow disease
Knowledge-focused CompletedThis completed study looked at blood vessel cells from 30 people with primary myelofibrosis, a rare bone marrow disorder. Researchers wanted to see if these cells act like stem cells that could be the origin of the disease. By growing the cells in the lab, they aimed to understan…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Scientists track lifespan of transfused blood in sickle cell kids
Knowledge-focused CompletedThis study looked at how long donor red blood cells survive in children with sickle cell disease who get regular blood transfusions. Researchers labeled a small part of the transfused blood with a harmless marker and tracked it over time. The goal was to better understand why som…
Phase 1 • Sponsor: Marianne Yee • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Blood cancer enzyme deficiency explored in new study
Knowledge-focused CompletedThis study looked at how often people with certain blood cancers or related conditions have an acquired deficiency of an enzyme called pyruvate kinase, which can cause anemia. Researchers took a single blood sample from 18 participants to measure enzyme activity and check for rel…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Anemia duration may predict ventilator days in ICU patients
Knowledge-focused CompletedThis study examined 236 adults in a surgical intensive care unit who needed a breathing machine for more than 4 days. Researchers wanted to see if the length of time a patient had anemia (low red blood cells) was linked to how long they stayed on the ventilator. The goal was to b…
Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Which iron pill works best? small study tests natural vs. standard supplements
Knowledge-focused CompletedThis completed study looked at how well healthy pre-menopausal women with low iron stores absorb iron from two different supplements: Spatone (a natural iron-rich water) and ferrous sulphate (a standard iron pill). Fourteen women took three different doses (5, 10, and 15 mg) of e…
Sponsor: King's College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Diet sheds light on iron deficiency in obesity
Knowledge-focused CompletedThis study looked at how weight loss from a calorie-restricted diet affects iron levels in people with obesity and iron deficiency. Researchers measured a protein called hepcidin, which controls iron in the body, along with iron levels before and after a 60-day diet. The goal was…
Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Hungarian ICU doctors quizzed on blood transfusion habits
Knowledge-focused CompletedThis completed study surveyed 97 Hungarian anesthesiologists and intensive care doctors about how they decide when to give blood transfusions to critically ill patients. The focus was on whether they use certain physiological signs (like lactate levels or oxygen saturation) recom…
Sponsor: Pest County Flór Ferenc Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Twin pregnancy complication may affect Kids' hearts and metabolism years later
Knowledge-focused CompletedThis study followed 179 children aged 4 to 16 who were born from twin pregnancies complicated by twin-to-twin transfusion syndrome (TTTS). Researchers checked their heart function, blood pressure, kidney health, and blood sugar control to see if the condition during pregnancy cau…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New screening method may catch kidney problems earlier in sickle cell patients
Knowledge-focused CompletedThis study looked at whether a special kidney scan (scintigraphy) can find early kidney damage in children and young adults with sickle cell disease better than standard tests. 18 patients were checked during their annual visit. The goal is to catch kidney problems sooner so trea…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Healthy volunteers needed to test new myelofibrosis drug's absorption
Knowledge-focused CompletedThis study looked at how well two different capsule forms of TP-3654 are absorbed by the body and whether taking them with food changes absorption. It involved 24 healthy adults and was completed. The results will help design future studies for people with myelofibrosis, a bone m…
Phase 1 • Sponsor: Sumitomo Pharma America, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Anemia in kids may be tied to bigger hearts, study finds
Knowledge-focused CompletedThis study explored whether low hemoglobin (anemia) is linked to an enlarged heart (cardiomegaly) in children up to 18 years old. Researchers used chest X-rays and echocardiograms to check for heart enlargement in 56 anemic children. The goal was to better understand how anemia a…
Sponsor: Universitas Sumatera Utara • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Iron pills may boost vaccine power in pregnancy, study hints
Knowledge-focused CompletedThis study looked at whether iron supplements improve how well vaccines work in pregnant women with anemia (low iron). Researchers compared their immune responses to tetanus, diphtheria, and COVID-19 vaccines against women without anemia. The goal was to see if correcting iron de…
Sponsor: University of Oxford • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Simple blood test could transform iron monitoring in thalassemia
Knowledge-focused CompletedThis study tested a new, simpler method to measure iron buildup inside red blood cells of people with beta thalassemia major. The goal was to find a cheaper and easier way to monitor iron overload compared to current tests. Researchers analyzed blood samples from 100 patients to …
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:04 UTC
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Pregnancy anemia study: iron pills under the microscope
Knowledge-focused CompletedThis study looked at how well pregnant women with iron deficiency anemia tolerate and stick with oral iron therapy. Researchers tracked side effects and checked if iron levels improved using blood tests. The goal was to better understand how to treat this common condition during …
Sponsor: The Royal Wolverhampton Hospitals NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Toddler milk may shield kids from iron deficiency, study hints
Knowledge-focused CompletedThis completed study looked at 830 two-year-olds in France to see if drinking toddler milk formula helps prevent iron deficiency, a common problem that can affect brain development. Researchers checked iron levels in blood and asked parents about diet and background. The goal is …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Neighborhood chats may help overcome COVID-19 testing mistrust
Knowledge-focused CompletedThis study tested whether weekly community-led group discussions could improve trust and openness to COVID-19 testing and vaccination. Fifty-seven adults from nine housing agencies took part in online meetings and completed surveys over six months. The goal was to see if peer-led…
Sponsor: Old Dominion University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Scientists test designer immune molecules in autoimmune diseases
Knowledge-focused CompletedThis study looked at whether specially engineered versions of a natural immune protein (IL-2) can selectively boost regulatory T cells, which help calm the immune system. Researchers took blood samples from 67 people with various autoimmune or inflammatory conditions and tested t…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Preterm babies often get extra blood transfusions, study finds
Knowledge-focused CompletedThis study looked at 201 very premature babies born before 31 weeks to see how often they received blood transfusions that went beyond French guidelines. Researchers found that many transfusions were given even when not recommended, possibly due to the babies' fragile health. The…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Scientists probe immune cells behind rare anemia
Knowledge-focused CompletedThis study looked at how certain immune cells, called T cells, behave in people with autoimmune hemolytic anemia, a condition where the body attacks its own red blood cells. Researchers compared blood samples from 27 patients and healthy volunteers to understand the disease bette…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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No more needles? AI may spot iron deficiency in kids from photos
Knowledge-focused CompletedThis study gathered information from 250 children aged 6 months to 6 years to develop artificial intelligence that can estimate iron levels from images and videos. The goal is to create a non-invasive way to screen for iron deficiency, replacing blood tests. Parents and doctors a…
Sponsor: Danone Asia Pacific Holdings Pte, Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Massive PNH registry reveals Real-World treatment safety
Knowledge-focused CompletedThis study collected health information from over 6,000 people with Paroxysmal Nocturnal Hemoglobinuria (PNH), a rare blood disorder. The goal was to track the safety of two medications, Soliris and Ultomiris, and to understand how PNH changes over time. Participants were followe…
Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Turkish myelofibrosis Patients' treatment patterns revealed in new study
Knowledge-focused CompletedThis study reviewed medical records of 355 people in Turkey with myelofibrosis (a type of bone marrow cancer) who were treated with the drug ruxolitinib for at least 3 months. Researchers collected information on patient demographics, disease characteristics, and how the drug was…
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Scientists uncover clues to inflammation in rare bone marrow disease
Knowledge-focused CompletedThis study looked at 70 people—some with primary myelofibrosis and some healthy—to understand how certain immune cells called MDSCs fuel inflammation in this rare bone marrow disease. Researchers also checked how these cells change with treatment and whether they help form new bl…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Which donor search strategy saves more lives?
Knowledge-focused CompletedThis study looked at 1,753 patients needing a stem cell transplant for blood cancers or other serious blood disorders. Researchers compared two strategies: first searching for a matched unrelated donor, then trying an alternative donor if needed, versus going straight to an alter…
Sponsor: Center for International Blood and Marrow Transplant Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Blood transfusions in heart surgery: friend or foe for anemic patients?
Knowledge-focused CompletedThis study looked at over 13,000 adults who had heart surgery to understand how blood transfusions given during the operation might explain why patients with anemia before surgery are more likely to have complications afterward. The goal is to help doctors make better decisions a…
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Could iron pills make vaccines work better?
Knowledge-focused CompletedThis study looked at whether giving oral iron supplements to iron-deficient women in Kenya before or at the same time as vaccination improves their immune response. 180 women received iron either before or with three vaccines (COVID-19, meningitis, and typhoid), or a placebo. The…
Sponsor: Nicole Stoffel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Scientists probe why leg sores plague sickle cell patients
Knowledge-focused CompletedThis study looked at why people with sickle cell disease often get hard-to-heal leg ulcers. Researchers measured blood flow, nerve function, and blood markers in 70 patients with and without ulcers. The goal was to better understand what causes these wounds, not to test a new tre…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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New study tracks PNH patients in china to uncover disease patterns
Knowledge-focused CompletedThis completed study followed 724 people in China with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood disorder. Researchers aimed to better understand how the disease progresses and how patients respond to different treatments, including the newly available drug eculizum…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Warm-Up secrets revealed: study tests best way to boost soccer skills
Knowledge-focused CompletedThis study looked at how different stages of muscle warm-up affect knee joint awareness, jumping power, agility, and balance in 25 professional youth soccer players under 18. Players were tested during rest, after warm-up, and when fatigued. The goal was to understand how warm-up…
Sponsor: Necmettin Erbakan University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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First human test of LP-005 drug completed in healthy volunteers
Knowledge-focused CompletedThis early-stage study tested a new drug, LP-005, in 68 healthy adults aged 18 to 50. The main goal was to check if the drug is safe and how the body handles it. This information will help design future studies for people with a rare blood disorder called PNH.
Phase 1 • Sponsor: Longbio Pharma • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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New drug interaction study for myelofibrosis treatment begins
Knowledge-focused CompletedThis phase 1 trial in 40 healthy adults tests how TQ05105, a drug for myelofibrosis, interacts with other medications that affect liver enzymes. Participants take TQ05105 alone and then with either itraconazole or rifampicin to see how these drugs change TQ05105 levels in the bod…
Phase 1 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Sickle cell study reveals hidden clues in blood vessels
Knowledge-focused CompletedThis study measured blood vessel function in 49 adults with sickle cell disease to see how it relates to disease severity. Researchers used laser and pulse wave tests to check small and large blood vessels. The goal was to better understand the disease, not to test a new treatmen…
Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Hidden iron deficiency may worsen fibromyalgia pain
Knowledge-focused CompletedThis study looked at how many women with fibromyalgia at a pain clinic might have iron deficiency. 81 women completed a questionnaire about symptoms like heavy periods and past iron issues. The goal was to see if iron deficiency is common and if treating it could help their pain.
Sponsor: McMaster University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Iron infusion safety check: rare blood disorder studied in 50 patients
Knowledge-focused CompletedThis study looked at whether intravenous iron treatments (ferric carboxymaltose or ferric derisomaltose) can cause a rare side effect called methemoglobinemia, where blood can't carry oxygen properly. Researchers measured methemoglobin levels in 50 anemic patients before and afte…
Sponsor: Claudia Seiler • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Rare cholesterol disorder linked to hidden eye risk
Knowledge-focused CompletedThis study looked at 10 people with rare genetic conditions that cause very low cholesterol and trouble absorbing vitamins. Researchers measured a protective pigment in the eye called macular pigment, which may be low in these patients and could explain why some still develop vis…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New registry aims to unravel severe blood disorders in youth
Knowledge-focused CompletedThis completed registry study followed 80 children and young adults with severe immune cytopenias, including immune thrombocytopenia, autoimmune hemolytic anemia, and Evans syndrome. Researchers observed participants over up to 4 years to improve diagnosis and track the disease c…
Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Can farming plus nutrition help stop child stunting? kenya study finds out.
Knowledge-focused CompletedThis study looked at whether adding nutrition and hygiene support to an existing farming program can reduce malnutrition in pregnant women and their children. About 1,200 pregnant women in Kenya took part, with half getting the extra nutrition help. The goal was to see if childre…
Sponsor: Fabian Rohner • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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IV iron drug may cause rare blood disorder, new study investigates
Knowledge-focused CompletedThis completed study looked at how often a rare blood condition called methemoglobinemia occurs after treatment with the IV iron drug ferric carboxymaltose. Researchers measured methemoglobin levels in nearly 1,000 adults receiving the drug for iron-deficiency anemia and compared…
Sponsor: Ordu University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Blood disorder survey in bangladesh reveals hidden genetic burden
Knowledge-focused CompletedThis completed study looked at how often hemoglobin disorders (like thalassemia and sickle cell disease) occur in people visiting a hospital in Chattogram, Bangladesh. Researchers tested blood samples from 760 volunteers using advanced methods to find different hemoglobin types. …
Sponsor: Bangladesh Bioscience Research Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Beef for brainpower: study tests 30-Day diet on young Women's cognition
Knowledge-focused CompletedThis study looked at whether eating beef every day for 30 days could improve thinking and visual skills in healthy young women. 80 women aged 18-40 took part, with one group eating beef and the other eating a plant-based protein. Researchers measured their performance on a 3D tra…
Sponsor: Texas A&M University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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New study sheds light on anemia in endocarditis patients
Knowledge-focused CompletedThis completed study looked at 209 patients with bacterial endocarditis, a serious heart valve infection, to understand how common anemia is and what causes it. Researchers measured blood markers for inflammation and anemia from diagnosis up to 6 months after hospital discharge. …
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Which Warm-Up boosts young Goalkeepers' performance best?
Knowledge-focused CompletedThis study tested how different warm-up protocols affect flexibility, explosive power, and balance in 15 adolescent male football goalkeepers. Participants performed aerobic running, static stretching, dynamic stretching, or movement preparation before tests. The goal is to ident…
Sponsor: Uşak University • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:02 UTC
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New study tracks High-Risk pregnancies to improve newborn health
Knowledge-focused CompletedThis study followed 17 pregnant women and their babies who were at high risk for early onset severe hemolytic disease of the fetus and newborn (EOS-HDFN). The goal was to see how the condition is currently managed and what outcomes occur. No new drugs were tested; instead, resear…
Sponsor: Janssen Research & Development, LLC • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:16 UTC
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Small step toward gene therapy for rare anemia
Knowledge-focused CompletedThis pilot study tested whether a combination of two drugs (G-CSF and plerixafor) could safely collect enough stem cells from the blood of children with Fanconi anemia for future gene therapy. Only 4 patients took part, and the main goal was to see if the cell collection process …
Phase 1/2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:06 UTC
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Can we predict dangerous spleen attacks in sickle cell babies?
Knowledge-focused CompletedThis study followed 58 babies with sickle cell disease from 3 months to 2 years old to find early clues that might predict a life-threatening spleen complication called acute splenic sequestration. Researchers took blood samples and used special scans to measure spleen size and f…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:01 UTC
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Iron deficiency may blunt vaccine protection, study suggests
Knowledge-focused CompletedThis study looked at whether iron deficiency anemia makes COVID-19 vaccines less effective in young women. Researchers gave intravenous iron to 121 participants and measured their immune responses. The goal was to see if correcting iron deficiency could boost vaccine protection.
Sponsor: Jomo Kenyatta University of Agriculture and Technology • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:40 UTC