Could a low dose hormone drug slow down Aging-Related diseases?

NCT ID NCT03312400

Recruiting now Disease control Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 17 times

Summary

This study tests if a low dose of the hormone drug danazol can safely slow down telomere shortening in people with telomere diseases. Telomeres are protective caps on our DNA that get shorter as we age, and people with certain gene changes can develop serious bone marrow, lung, or liver problems. About 40 participants aged 3 and older will take danazol twice a day for a year and be monitored for safety and effects on their telomeres and disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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TELOMERE DISEASE