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New study sheds light on anemia in endocarditis patients

NCT ID NCT04840225

Knowledge-focused Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 209 patients with bacterial endocarditis, a serious heart valve infection, to understand how common anemia is and what causes it. Researchers measured blood markers for inflammation and anemia from diagnosis up to 6 months after hospital discharge. The goal was to better characterize anemia in these patients, which could guide future care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better understand and manage anemia in endocarditis patients, potentially improving recovery.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly change patient care. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

209 people

The number who actually took part.

Started

Mar 2021

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

100 patients with IE, 30 undergoing elective TAVI/TECAR, 30 with non-IE bacterial infections and 30 healthy blood donors

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

IE-patients: Inclusion Criteria: • Infectious endocarditis, defined by Duke criteria Exclusion Criteria: • Known rheumatic disease or immune defect TAVI/TEVAR patients: Inclusion Criteria: • Scheduled for a TAVI/TEVAR procedure Exclusion criteria: * Clinical suspicion of infection * Known rheumatic disease or immune defect Bacterial patients without IE (short infection): Inclusion criteria * Patients admitted with an infection with gram positive bacteria, without IE Exclusion criteria * Known rheumatic disease or immune defect Blood donors: Exclusion criteria: * Antibiotic treatment within the last 2 months * Cancer, rheumatic disease or other known inflammatory disease * Surgery within the last 3 months * Pregnancy

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Conditions

The condition(s) this trial relates to.

anemia bacterial endocarditis infective endocarditis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anemia Endocarditis, bacterial

Contacts and locations

Locations

  • Rigshospitalet

    Copenhagen, 2100, Denmark

More trials for these conditions

Other studies related to the condition(s) this trial covers.