Rigshospitalet, Denmark

This study is testing whether adjusting radiation treatment daily based on a patient's changing anatomy can reduce severe side effects like swallowing problems and dry mouth. It will involve 40 patients with head and neck cancer who are receiving radiotherapy with the goal of cur…

This study is testing whether a modified version of standard heart attack treatment can reduce damage to the heart muscle and prevent future heart failure. The trial involves 1,800 patients who are having a severe type of heart attack (STEMI) and receiving emergency artery-openin…

This study is testing whether people with severe nasal polyps who have been symptom-free for at least a year while taking biologic drugs (Nucala or Dupixent) can safely stop taking them. Researchers will randomly assign 66 patients to either continue their medication or stop it, …

This study is testing whether an automated insulin delivery system (CamAPS FX) helps women with type 1 diabetes better control their blood sugar before and during pregnancy compared to their usual insulin methods. It aims to improve health for both mother and baby, focusing on ti…

This study is testing if a daily pill called semaglutide (Rybelsus) is a safe and effective way to control high blood sugar in people who have recently received a kidney transplant. It will compare the pill to a placebo (dummy pill) in 104 patients, with both groups also receivin…

This study is testing if patients with chronic sinusitis and nasal polyps can safely take their biologic medicines (dupilumab or mepolizumab) less frequently. About 135 adults in Denmark who are already stable on these drugs will try extending the time between doses from 4 weeks …

This study is testing whether putting a new heart device in immediately after removing an infected one is safer and more effective than the standard approach of waiting. It involves 176 patients with serious infections of their pacemakers or defibrillators. The goal is to see if …

This study aims to fight antibiotic resistance by helping doctors in Kyrgyzstan prescribe antibiotics more wisely for common respiratory infections like coughs and colds. It will test if giving patients an information leaflet about when antibiotics are needed, and using a simple …

This study is testing if a personalized exercise and nutrition program before a stem cell transplant helps patients recover better. It will compare patients who do this 'prehabilitation' to those who receive standard care alone. The main goal is to see if the program improves pat…

This large trial is testing two potential improvements to standard radiation therapy for men with intermediate or high-risk prostate cancer. It will see if delivering a higher, focused dose of radiation directly to visible tumors within the prostate improves cure rates. It will a…

This study is testing whether a 3D ultrasound scan of removed skin cancer tissue can accurately measure how close the cancer cells are to the edges of the removed sample. Researchers will compare the ultrasound measurements to the standard laboratory analysis (histopathology) per…

This study is testing a new, high-resolution ultrasound technique to see the tiniest blood vessels inside thyroid nodules. Researchers hope that by mapping these blood vessels, they can better tell the difference between harmless and potentially cancerous nodules. This could help…

This study is testing if a higher dose of a common steroid (dexamethasone) can better control pain after minimally invasive lung cancer surgery. It focuses on patients who are identified as being highly sensitive to pain before their operation. Researchers will compare pain level…

This study tests a program to help children undergoing cancer treatment stay connected to their school. It uses remote-controlled robots so kids can attend class from home or the hospital, along with a dedicated school navigator for support. Researchers want to see if this approa…

This study is testing if a personalized, 12-week exercise program can help adults with long-lasting symptoms after a concussion. Researchers will measure if the program helps patients exercise for longer periods without making their symptoms worse. They will also use brain scans …

This study is testing whether a personalized rehabilitation program helps survivors of sudden cardiac arrest return to work better than standard care alone. It will involve 214 adult survivors who were working before their cardiac arrest. The main goal is to see if more people ar…

This study is testing whether injections of a purified form of Botox (incobotulinumtoxin-A) around the nerves in the legs can safely reduce pain for people with diabetic neuropathy. 80 participants with long-term, symmetrical foot pain will receive injections every 12 weeks for 2…

This study aims to better predict which blood cancer patients are at high risk for dangerous side effects, like cytokine release syndrome (CRS), after receiving immunotherapy. Researchers will monitor 100 patients continuously with wireless sensors and blood tests to look for ear…

This European study is collecting information about how well different lymphatic treatments work for people with congenital heart disease or primary lymphatic disorders. Researchers will track 500 patients across multiple countries to see if early diagnosis and targeted procedure…

This study aims to understand why up to 25% of children lose their ability to speak after surgery for a specific type of brain tumor. Researchers will follow 1,000 children from Nordic countries, collecting detailed information about their surgery, recovery, and genetics. The goa…

This study aims to understand how and why nerve damage occurs in people with Waldenström's macroglobulinemia, a type of blood cancer. Researchers will examine 90 patients who have both the cancer and symptoms of nerve problems to identify patterns and potential markers for the co…

This study aims to understand how well patients grasp the information they receive before major abdominal cancer surgery and how their expectations compare to their actual recovery. Researchers will follow 90 patients undergoing surgeries like pancreatic or liver removal, asking …

This observational study aims to understand how certain markers in brain fluid can help detect infections in patients with acute brain injuries who have drainage tubes. Researchers will monitor 148 patients in Denmark to see if lactate levels in brain fluid can predict infections…

This study aims to understand how suddenly stopping all exercise affects appetite control in healthy, active men. Researchers will have 40 participants either continue their normal activity or stop all exercise and limit walking for two weeks. They will measure how much people ea…

This study aims to better understand how Alzheimer's disease affects the brain's blood flow and sugar use, especially in people who also have type 2 diabetes. Researchers will use advanced brain scans (PET scans) to compare three groups: Alzheimer's patients without diabetes, Alz…

This study is testing whether a wireless chest sensor can help nurses better monitor patients recovering from major spinal deformity surgery. The sensor continuously tracks heart rate, breathing, and other vital signs, sending alerts to nurses' phones, aiming to catch problems ea…

This study aims to test an online screening system to better identify mental health disorders in children and teenagers born with congenital heart disease. Researchers will enroll about 4,800 young people in Denmark, asking their parents to complete questionnaires about emotional…

This study uses a special full-body PET scanner to see how two natural gut hormones (GIP and GLP-1) affect how the body uses sugar and how blood flows to different organs. It involves healthy volunteers and people with type 2 diabetes. The goal is to gather detailed information t…

This study aims to find out how common a specific heart condition called cardiac amyloidosis is in men over 65 who have chest pain but no signs of blocked heart arteries. Researchers will examine 300 participants using blood tests, heart scans, and imaging to look for this hidden…

This study aims to understand how different ways of presenting artificial intelligence (AI) predictions affect doctors' judgment when assessing the risk of preterm birth. Doctors specializing in pregnancy care will review simulated patient cases online, make decisions, and see ho…