Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Silent after surgery: new study hunts for clues to mysterious speech loss in kids

NCT ID NCT02300766

Knowledge-focused Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This study follows 1,000 children who have surgery for a brain tumor in the back part of the brain. Up to 1 in 4 of these children develop a condition called Cerebellar Mutism Syndrome, where they lose the ability to speak. Researchers want to understand why this happens and how to treat it better.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 2,000 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Oct 2014

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All children (0-18 years) with a tumour in the posterior fossa (cerebellum/4th ventricle/brainstem ) requiring surgery or open biopsy at one of the participating centres.

Ages

Up to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \< 18 years at the date of first imaging showing this tumour * Tumour in the cerebellum/4th ventricle/brainstem with intention to treat with surgical resection or open biopsy. Second and further surgeries are also included. * Informed consent from custodial parent(s) Exclusion Criteria: * None

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Infratentorial neoplasms are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

infratentorial cancer infratentorial neoplasm mutism neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infratentorial neoplasms MUTISM

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    31 sites in 14 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Aalborg University Hospital

    RECRUITING

    Aalborg, 9100, Denmark

  • Aarhus University Hospital

    RECRUITING

    Aarhus, 8000, Denmark

  • Alder Hey Childrens NHS Foundation Trust

    RECRUITING

    Liverpool, United Kingdom

  • Haukeland University Hospital

    RECRUITING

    Bergen, Norway

  • Helsinki University Central Hospital

    RECRUITING

    Helsinki, Finland

  • Hospital of Lithuanian University of Health Sciences Kauno klinikos

    RECRUITING

    Kaunas, Lithuania

  • Karolinska University Hospital

    RECRUITING

    Stockholm, Sweden

  • Kuopio University Hospital

    NOT_YET_RECRUITING

    Kuopio, Finland

  • Linköping University Hospital

    RECRUITING

    Linköping, Sweden

  • Medical University of Vienna

    RECRUITING

    Vienna, Austria

  • Motol University Hospital

    RECRUITING

    Prague, Czechia

  • Odense University Hospital

    RECRUITING

    Odense, 5000, Denmark

  • Oslo University Hospital

    NOT_YET_RECRUITING

    Oslo, Norway

  • Ospedale Pediatrico Bambino Gesù

    RECRUITING

    Rome, Rome, 00165, Italy

  • Oulu University Hospital

    NOT_YET_RECRUITING

    Oulu, Finland

  • Radboud University Nijmegen Medical Centre

    RECRUITING

    Nijmegen, Gelderland, 6525, Netherlands

  • Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, Sweden

  • Sant Joan de Déu Barcelona Hospital

    RECRUITING

    Barcelona, 08950, Spain

  • Semmelweis University, 2nd Dept of Pediatrics

    RECRUITING

    Budapest, Hungary

  • Skåne University Hospital

    RECRUITING

    Skåne, Sweden

  • St. Olav's Hospital

    RECRUITING

    Trondheim, Norway

  • Tampere University Hospital

    NOT_YET_RECRUITING

    Tampere, Finland

  • Turku University Hospital

    NOT_YET_RECRUITING

    Turku, Finland

  • UMC Groningen

    ACTIVE_NOT_RECRUITING

    Groningen, Netherlands

  • UMC Utrecht

    RECRUITING

    Utrecht, Netherlands

  • University Hospital Leuven

    RECRUITING

    Leuven, Belgium

  • University Hospital of North Norway

    NOT_YET_RECRUITING

    Tromsø, Norway

  • University Hospital of Umeå

    RECRUITING

    Umeå, Sweden

  • University of Leipzig Medical Center

    RECRUITING

    Leipzig, Germany

  • Universitätsklinikum Tübingen

    RECRUITING

    Tübingen, 72076, Germany

  • Uppsala University Hospital

    RECRUITING

    Uppsala, Sweden