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Gene therapy breakthrough offers hope for blood disorder patients

NCT ID NCT06291961

First seen Feb 14, 2026 · Last updated May 23, 2026 · Updated 13 times

Summary

This early-stage trial tested a single dose of CS-101, a gene therapy, in 9 people with beta-thalassemia major, a severe blood disorder requiring lifelong transfusions. The main goals were to check safety and see if the treatment helps the body produce healthy red blood cells. While not a cure, it aims to reduce or eliminate the need for regular blood transfusions.

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Contacts and locations

Locations

  • Children's Hospital of Fudan University

    Shanghai, Shanghai Municipality, China

  • Ruijin Hospital Shanghai JiaoTong University School of Medicine

    Shanghai, Shanghai Municipality, China

  • The First Affiliated Hospital of Guangxi Medical University

    Nanning, Guangxi, China

Conditions

Explore the condition pages connected to this study.