New pill shows promise in shrinking spleens for myelofibrosis patients
NCT ID NCT05020652
First seen Jan 04, 2026 · Last updated Jun 18, 2026 · Updated 30 times
Summary
This study tested a new drug called TQ05105 in 107 people with moderate to high-risk myelofibrosis, a rare bone marrow disorder that often causes an enlarged spleen. The goal was to see if TQ05105 could shrink the spleen better than the standard drug hydroxyurea. Participants took either TQ05105 or hydroxyurea for 24 weeks, and doctors measured spleen size using scans. The trial is complete, and results will show if TQ05105 is a more effective treatment option.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Guangdong Provincial Peoples Hospital
Guangzhou, Guangdong, 510055, China
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Institute of Hematology & Blood Diseases Hostpital, Chinese Academy of medical sciences & Peking Union Medical College
Tianjin, Tianjin Municipality, 300020, China
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, 100005, China
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West China School of Medicine / West China Hospital, Sichuan University
Chengdu, Sichuan, 610041, China
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.