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Blood transfusions in heart surgery: friend or foe for anemic patients?

NCT ID NCT07092683

Knowledge-focused Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at over 13,000 adults who had heart surgery to understand how blood transfusions given during the operation might explain why patients with anemia before surgery are more likely to have complications afterward. The goal is to help doctors make better decisions about when to give transfusions and how to reduce risks for anemic patients. The study did not test a new treatment but instead analyzed existing data to find patterns.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

13,683 people

The number who actually took part.

Started

Jan 2025

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Eligible patients for inclusion were those aged 18 or older undergoing elective cardiac surgery with CPB support at West China Hospital (WCH) from 22 December 2010 to 1 July 2017, and at The Second affiliated Hospital of Zhejiang University (SAHZU) from 1 September 2013 to 31 December 2024.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 and older ； * Undergoing elective cardiac surgery with cardiopulmonary bypass Exclusion Criteria: * preoperative mechanical circulatory support * ASA physical status VI-V * unplanned intra-hospital reoperations * catheter-based valve replacements, * heart tumours, * stent implantation surgeries, * coronary angiography, * transvascular valve clamping, * tetralogy of Fallot, * ventricular aneurysms, * cardiomyopathies,

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Conditions

The condition(s) this trial relates to.

anemia Negotiating

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anemia Cardiac surgery Mediation Transfusion

Contacts and locations

Locations

  • Department of Anesthesiology, Second Affiliated Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 330100, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.