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New hope for kids with rare kidney disease: drug may cut dialysis time

NCT ID NCT02205541

First seen May 06, 2026 · Last updated Jun 18, 2026 · Updated 10 times

Summary

This study tested whether the drug eculizumab can help children with a serious kidney disease called STEC-HUS, which is caused by a type of E. coli infection. About 100 children aged 1 month to 18 years received either eculizumab or a placebo. The main goal was to see if the drug reduces the number of days they need dialysis. The study aims to provide clear evidence on whether this treatment is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Anne de Bretagne University Hospital

    Rennes, 35056, France

  • Clocheville Hospital

    Tours, 37044, France

  • Jeanne de Flandre Hospital

    Lille, 59037, France

  • La Timone Hospital

    Marseille, France

  • Morvan Hospital

    Brest, 29609, France

  • Mother and Child Hospital

    Limoges, 87000, France

  • Mother and Child Hospital

    Nantes, 44000, France

  • Necker Hospital

    Paris, 75743, France

  • Pellegrin Hospital

    Bordeaux, 33000, France

  • Purpan Children Hospital

    Toulouse, 31059, France

  • Robert Debré Hospital

    Paris, 75019, France

  • Trousseau Hospital

    Paris, 75571, France

  • University Hospital

    Amiens, 80054, France

  • University Hospital

    Angers, 49100, France

  • University Hospital

    Besançon, 25030, France

  • University Hospital

    Grenoble, 60107, France

  • University Hospital

    Montpellier, 34295, France

  • Women, Mother and Child Hospital

    Lyon, 69500, France

Conditions

The condition(s) this trial relates to.

hemolytic-uremic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.