Can a drug shorten dialysis for kids with a rare kidney disease?
NCT ID NCT02205541
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether the drug eculizumab (Soliris) can help children with a severe kidney condition called STEC-HUS recover faster. The trial gave 100 children either eculizumab or a placebo over several weeks. The main goal was to see if the drug reduces the number of days they need dialysis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- eculizumab (Soliris)
- What this could lead to
- If it works, this could provide the first proven treatment to shorten kidney dialysis and speed recovery in children with STEC-HUS.
- What could go wrong
- This is an early Phase 3 trial with only 100 children, and previous studies have shown mixed results. The drug may not reduce dialysis time or could cause side effects like infections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Anne de Bretagne University Hospital
Rennes, 35056, France
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Clocheville Hospital
Tours, 37044, France
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Jeanne de Flandre Hospital
Lille, 59037, France
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La Timone Hospital
Marseille, France
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Morvan Hospital
Brest, 29609, France
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Mother and Child Hospital
Limoges, 87000, France
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Mother and Child Hospital
Nantes, 44000, France
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Necker Hospital
Paris, 75743, France
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Pellegrin Hospital
Bordeaux, 33000, France
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Purpan Children Hospital
Toulouse, 31059, France
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Robert Debré Hospital
Paris, 75019, France
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Trousseau Hospital
Paris, 75571, France
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University Hospital
Amiens, 80054, France
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University Hospital
Angers, 49100, France
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University Hospital
Besançon, 25030, France
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University Hospital
Grenoble, 60107, France
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University Hospital
Montpellier, 34295, France
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Women, Mother and Child Hospital
Lyon, 69500, France