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New pill could help PNH patients with persistent anemia

NCT ID NCT07052838

First seen Jan 04, 2026 · Last updated May 22, 2026 · Updated 23 times

Summary

This study tested a new tablet, HSK39297, in 36 adults with paroxysmal nocturnal hemoglobinuria (PNH) who still had anemia despite standard treatment. The goal was to see if the drug could raise hemoglobin levels and reduce the need for blood transfusions. Participants took the tablet while continuing their usual anti-C5 antibody therapy.

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Contacts and locations

Locations

  • The First Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, China

  • The First Affiliated Hospital, College of Medicine, Zhejiang University

    Hangzhou, Zhejiang, China

Conditions

Explore the condition pages connected to this study.