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Diet sheds light on iron deficiency in obesity

NCT ID NCT06104800

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how weight loss from a calorie-restricted diet affects iron levels in people with obesity and iron deficiency. Researchers measured a protein called hepcidin, which controls iron in the body, along with iron levels before and after a 60-day diet. The goal was to understand the link between obesity-related inflammation and poor iron status. 42 adults completed the study, comparing two high-protein diets (with or without red meat).

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Jan 2024

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Phase 1 * Signing of the informed consent form * Both sexes * Adults over 18 years of age * BMI of 18.5 and under 40 kg/m2 Phase 2 * Both sexes * Adults older than 18 years * People with obesity (BMI of 30 to 40 kg/m2) and serum iron \< 50 micrograms/dL. * Total cholesterol less than 240 mg/dL (with the diet plan 20% decrease). Exclusion Criteria: * Any type of diabetes. * Patients with renal disease diagnosed by a physician. * Patients with acquired diseases that secondarily produce obesity and diabetes. * Patients who have suffered a cardiovascular event. * Weight loss \> 3 kg in the last 3 months. * Patients with catabolic diseases such as cancer and acquired immunodeficiency syndrome. * Pregnancy. * Treatment with any drug treatment: 1. Treatment with antihypertensive drugs (loop or potassium-sparing diuretics, angiotensin-converting enzyme inhibitors (ACE inhibitors), angiotensin II receptor blockers, alpha blockers, calcium antagonists, beta blockers). 2. Treatment with hypoglycemic agents (sulfonylureas, biguanides, incretins) or insulin and antidiabetics. 3. Treatment with statins, fibrates or other drugs to control dyslipidemia. 4. Use of steroid drugs, chemotherapy, immunosuppressants or radiotherapy. 5. Anorectics or drugs that accelerate weight loss. 6. Any drug or medication that activates intestinal motility (cisapride, dimethicone, domperidone, metoclopramide, trimebutine). 7. Laxatives or antispasmodics 4 weeks prior to the study h) Antibiotic treatment 2 months prior to the study. * Patients who have suffered a blood loss of more than 500 ml or recent gastrointestinal tract perforation. * Patients with a smoking index greater than 21. * Consumption of large amounts of alcohol (14 drinks for women or 21 drinks for men in a normal week). * Consumption of any recreational psychoactive substance. * Treatment with any medication that influences inflammation or iron metabolism (proton pump inhibitors, antacids, bisphosphonates, bile acid or calcium sequestrants). * Patients who are vegetarians * Allergy or intolerance to any food mentioned in the proposed pantry such as egg, dairy, fish, tuna, chicken, beans, lima beans and/or lentils. * Unwillingness to consume any of the foods listed in the proposed pantry.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

    México, Mexico

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