Scientists probe the root cause of a rare bone marrow disease
NCT ID NCT07607392
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at blood vessel cells from 30 people with primary myelofibrosis, a rare bone marrow disorder. Researchers wanted to see if these cells act like stem cells that could be the origin of the disease. By growing the cells in the lab, they aimed to understand how the disease develops.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help explain how primary myelofibrosis starts, potentially pointing toward new treatment targets.
- What could go wrong
- This is a small, completed observational study with only 30 participants. It does not test any treatment, so it may not lead directly to new therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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30 people
The number who actually took part.
- Started
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May 2023
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy volunteers will be enrolled among people working in the Institutions where the project is conducted (San Matteo Foundation and Pavia University in Pavia and IEO in Milan)
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * availability to understand and sign the informed consent Exclusion Criteria: * no known concurrent hematologic disease or condition that can affect the interpretation of the results
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Italy, 27100, Italy
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Other studies related to the condition(s) this trial covers.
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